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pro vyhledávání: '"Stefan Heinzmann"'
Autor:
Stefan Heinzmann
Master's Thesis from the year 2018 in the subject Economics - International Economic Relations, grade: 1.0, Dresden Technical University (Zentrum für Internationale Studien), language: English, abstract: This thesis breaks down the reason for deep e
Publikováno v:
Applied Microbiology and Biotechnology. 69:532-536
To improve the production of the lantibiotic subtilin in Bacillus subtilis ATCC 6633, two genetic engineering strategies were followed. Firstly, additional copies of subtilin self-protection (immunity) genes spaIFEG have been integrated into the geno
Publikováno v:
Journal of Bacteriology. 187:822-828
Bacillus subtilis ATCC 6633 produces the cationic pore-forming lantibiotic subtilin, which preferentially acts on gram-positive microorganisms; self protection of the producer cells is mediated by the four genes spaIFEG . To elucidate the mechanism o
Publikováno v:
Molecular Microbiology. 47:1627-1636
Summary The subtilin gene cluster (spa) of Bacillus subtilis ATCC 6633 is organized in transcriptional units spaBTC, spaS, spaIFEG and spaRK. Specific binding of the response regulator protein SpaR to spaB, spaS and spaI DNA promoter fragments was sh
Publikováno v:
Journal of Biological Chemistry. 271:12294-12301
The lantibiotic nisin of Lactococcus lactis is matured from a ribosomally synthesized prepeptide by post-translational modification. Genetic and biochemical evidence suggests that genes nisB and nisC of the nisin gene cluster encode proteins necessar
Publikováno v:
Molecular microbiology. 47(6)
The subtilin gene cluster (spa) of Bacillus subtilis ATCC 6633 is organized in transcriptional units spaBTC, spaS, spaIFEG and spaRK. Specific binding of the response regulator protein SpaR to spaB, spaS and spaI DNA promoter fragments was shown by m
Publikováno v:
The Journal of biological chemistry. 278(1)
Nisin-producing Lactococcus lactis strains show a high degree of resistance to the action of nisin, which is based upon expression of the self-protection (immunity) genes nisI, nisF, nisE, and nisG. Different combinations of nisin immunity genes were
Autor:
Torsten, Stein, Stefan, Borchert, Peter, Kiesau, Stefan, Heinzmann, Stephan, Klöss, Cora, Klein, Markus, Helfrich, Karl-Dieter, Entian
Publikováno v:
Molecular microbiology. 44(2)
The production of the peptide antibiotic (lantibiotic) subtilin in Bacillus subtilis ATCC 6633 is highly regulated. Transcriptional organization and regulation of the subtilin gene cluster encompassing 11 genes was characterized. Two polycistronic mR