Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stefan Heinze-Milne"'
Autor:
Stephanie J. Kendall, Jodi E. Langley, Mohsen Aghdam, Bruce N. Crooks, Nicholas Giacomantonio, Stefan Heinze-Milne, Will J. Johnston, Melanie R. Keats, Sharon L. Mulvagh, Scott A. Grandy
Publikováno v:
Current Oncology, Vol 29, Iss 9, Pp 6350-6363 (2022)
Childhood and adolescent cancer survivors are disproportionately more likely to develop cardiovascular diseases from the late effects of cardiotoxic therapies (e.g., anthracycline-based chemotherapy and chest-directed radiotherapy). Currently, dexraz
Externí odkaz:
https://doaj.org/article/41d140ec943f44c98487c0771770d262
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Aerobic exercise is a promising intervention to attenuate frailty, but preclinical studies have used only male animals. We investigated the impact of voluntary aerobic exercise on frailty, biological age (FRailty Inferred Geriatric Health Timeline [F
Autor:
Stephanie Jane Kendall, Jodi E Langley, Bruce N Crooks, Nicholas Giacomantonio, Stefan Heinze-Milne, Will J Johnston, Melanie R Keats, Sharon L Mulvagh, Scott A Grandy
Publikováno v:
Healthy Populations Journal. 2
Introduction: Childhood and adolescent cancer survivors treated with anthracyclines and chest-directed radiation therapy have a much higher risk of developing cardiovascular complications into adulthood. Exercise is one intervention that may mitigate
Autor:
Scott A. Grandy, Chris M. Blanchard, Miroslaw Rajda, Nicholas Giacomantonio, David MacDonald, Tallal Younis, Stefan Heinze-Milne, Melanie R. Keats
Publikováno v:
Translational Journal of the American College of Sports Medicine. 6:1-11
Publikováno v:
The Lancet Healthy Longevity. 3:e83-e84
Autor:
Alice E. Kane, Kaitlyn M Keller, Stefan Heinze-Milne, Scott A. Grandy, Susan E. Howlett, Elise S Bisset
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
We investigated whether late-life changes in cardiac structure and function were related to high levels of frailty and inflammation in male and female mice. Frailty (frailty index), ventricular structure/function (echocardiography), and serum cytokin
Publikováno v:
The Journals of Gerontology: Series A. 74:275-282
A frailty index (FI) based on clinical deficit accumulation (FI-Clinical) quantifies frailty in aging mice. We aimed to develop a laboratory test-based murine FI tool (FI-Lab) and to investigate the effects of age and sex on FI-Lab scores, FI-Clinica
Publikováno v:
The Journals of Gerontology: Series A. 77:291-291
Publikováno v:
Mechanisms of Ageing and Development. 198:111523
We investigated whether maladaptive, age-associated changes in heart structure and function were linked to circulating testosterone levels. Male C57BL/6 mice had a gonadectomy (GDX) or sham surgery at 4 weeks and effects of GDX on the heart were exam
Publikováno v:
Circulation Research. 125
Objective: Low circulating testosterone levels are correlated with heart diseases in older adults. The belief that low testosterone contributes to poor health and promotes frailty has dramatically increased testosterone prescriptions in recent years.