Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefan Hajny"'
Autor:
Zhen Guo, Carla Valenzuela Ripoll, Antonino Picataggi, David R. Rawnsley, Mualla Ozcan, Julio A. Chirinos, Ezhilarasi Chendamarai, Amanda Girardi, Terrence Riehl, Hosannah Evie, Ahmed Diab, Attila Kovacs, Krzysztof Hyrc, Xiucui Ma, Aarti Asnani, Swapnil V. Shewale, Marielle Scherrer-Crosbie, Lauren Ashley Cowart, John S. Parks, Lei Zhao, David Gordon, Francisco Ramirez-Valle, Kenneth B. Margulies, Thomas P. Cappola, Ankit A. Desai, Lauren N. Pederson, Carmen Bergom, Nathan O. Stitziel, Michael P. Rettig, John F. DiPersio, Stefan Hajny, Christina Christoffersen, Abhinav Diwan, Ali Javaheri
Publikováno v:
JACC Basic Transl Sci
Guo, Z, Valenzuela Ripoll, C, Picataggi, A, Rawnsley, D R, Ozcan, M, Chirinos, J A, Chendamarai, E, Girardi, A, Riehl, T, Evie, H, Diab, A, Kovacs, A, Hyrc, K, Ma, X, Asnani, A, Shewale, S V, Scherrer-Crosbie, M, Cowart, L A, Parks, J S, Zhao, L, Gordon, D, Ramirez-Valle, F, Margulies, K B, Cappola, T P, Desai, A A, Pedersen, L N, Bergom, C, Stitziel, N O, Rettig, M P, DiPersio, J F, Hajny, S, Christoffersen, C, Diwan, A & Javaheri, A 2023, ' Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury ', JACC: Basic to Translational Science, vol. 8, no. 3, pp. 340-355 . https://doi.org/10.1016/j.jacbts.2022.09.010
Guo, Z, Valenzuela Ripoll, C, Picataggi, A, Rawnsley, D R, Ozcan, M, Chirinos, J A, Chendamarai, E, Girardi, A, Riehl, T, Evie, H, Diab, A, Kovacs, A, Hyrc, K, Ma, X, Asnani, A, Shewale, S V, Scherrer-Crosbie, M, Cowart, L A, Parks, J S, Zhao, L, Gordon, D, Ramirez-Valle, F, Margulies, K B, Cappola, T P, Desai, A A, Pedersen, L N, Bergom, C, Stitziel, N O, Rettig, M P, DiPersio, J F, Hajny, S, Christoffersen, C, Diwan, A & Javaheri, A 2023, ' Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury ', JACC: Basic to Translational Science, vol. 8, no. 3, pp. 340-355 . https://doi.org/10.1016/j.jacbts.2022.09.010
ObjectivesDetermine the role of apolipoprotein M (ApoM) in anthracycline (Dox) cardiotoxicity.BackgroundApoM binds the cardioprotective sphingolipid sphingosine-1-phosphate (S1P). Circulating ApoM is inversely associated with mortality in human heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0661923be6ea10183741312ef8961d2
https://doi.org/10.1016/j.jacbts.2022.09.010
https://doi.org/10.1016/j.jacbts.2022.09.010
Autor:
Anne Tybjærg-Hansen, Christina Christoffersen, N. Dalila, Stefan Hajny, M. Christoffersen, Lars Nielsen
Publikováno v:
Hajny, S, Christoffersen, M, Dalila, N, Nielsen, L B, Tybjærg-Hansen, A & Christoffersen, C 2020, ' Apolipoprotein M and Risk of Type 2 Diabetes ', Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 9, pp. 3046-3057 . https://doi.org/10.1210/clinem/dgaa433
Context Recent studies have discovered a role of apolipoprotein M (apoM) in energy metabolism, and observational analyses in humans suggest an association with type 2 diabetes. The causal relationship remains however elusive. Objective To investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cdf54d9dc050ae2413fcf569ed9fae
https://doi.org/10.1210/clinem/dgaa433
https://doi.org/10.1210/clinem/dgaa433
Publikováno v:
Hajny, S, Borup, A, Elsoe, S & Christoffersen, C 2021, ' Increased plasma apoM levels impair triglyceride turnover in mice ', B B A-Molecular and Cell Biology of Lipids, vol. 1866, no. 9, 158969 . https://doi.org/10.1016/j.bbalip.2021.158969
Objective: Apolipopmtein M (apoM) is an essential transporter of plasma Sphingosine-1 -Phosphate (S1P), typically attached to all lipoprotein classes, but with a majority bound to high density lipoproteins (HDL). ApoM-deficient mice display an increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5825dae3086fed9bffeeab147117f04a
https://pubmed.ncbi.nlm.nih.gov/34051379
https://pubmed.ncbi.nlm.nih.gov/34051379
Autor:
Stefan Hajny, Pernille M. Christensen, Christina Christoffersen, Lars Nielsen, Markus H. Bosteen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Christensen, P M, Bosteen, M H, Hajny, S, Nielsen, L B & Christoffersen, C 2017, ' Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes ', Scientific Reports, vol. 7, 14983 . https://doi.org/10.1038/s41598-017-15043-y
Scientific Reports
Christensen, P M, Bosteen, M H, Hajny, S, Nielsen, L B & Christoffersen, C 2017, ' Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes ', Scientific Reports, vol. 7, 14983 . https://doi.org/10.1038/s41598-017-15043-y
Sphingosine-1-phosphate (S1P) is a bioactive lipid implicated in e.g. angiogenesis, lymphocyte trafficking, and endothelial barrier function. Erythrocytes are a main source of plasma S1P together with platelets and endothelial cells. Apolipoprotein M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2667c8a232f69d5eec9b6c95b0fcd123
https://doi.org/10.1038/s41598-017-15043-y
https://doi.org/10.1038/s41598-017-15043-y
Autor:
Stefan Hajny, Christina Christoffersen
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 8, p 1636 (2017)
Hajny, S & Christoffersen, C 2017, ' A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation ', International Journal of Molecular Sciences, vol. 18, no. 8, 1636 . https://doi.org/10.3390/ijms18081636
International Journal of Molecular Sciences
Hajny, S & Christoffersen, C 2017, ' A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation ', International Journal of Molecular Sciences, vol. 18, no. 8, 1636 . https://doi.org/10.3390/ijms18081636
International Journal of Molecular Sciences
Hepatocytes, renal proximal tubule cells as well as the highly specialized endothelium of the blood brain barrier (BBB) express and secrete apolipoprotein M (apoM). ApoM is a typical lipocalin containing a hydrophobic binding pocket predominantly car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57674d7c822625f9892e1145e9566f9b
https://www.mdpi.com/1422-0067/18/8/1636
https://www.mdpi.com/1422-0067/18/8/1636