Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stefan H Stricker"'
Autor:
Bob A Hersbach, David S Fischer, Giacomo Masserdotti, Deeksha, Karolina Mojžišová, Thomas Waltzhöni, Diego Rodriguez‐Terrones, Matthias Heinig, Fabian J Theis, Magdalena Götz, Stefan H Stricker
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 9, Pp n/a-n/a (2022)
Abstract Despite the therapeutic promise of direct reprogramming, basic principles concerning fate erasure and the mechanisms to resolve cell identity conflicts remain unclear. To tackle these fundamental questions, we established a single‐cell pro
Externí odkaz:
https://doaj.org/article/7ee96a824f2445ee879799d35c3bf713
Autor:
Christopher T Breunig, Tamara Durovic, Andrea M Neuner, Valentin Baumann, Maximilian F Wiesbeck, Anna Köferle, Magdalena Götz, Jovica Ninkovic, Stefan H Stricker
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196015 (2018)
Novel applications based on the bacterial CRISPR system make genetic, genomic, transcriptional and epigenomic engineering widely accessible for the first time. A significant advantage of CRISPR over previous methods is its tremendous adaptability due
Externí odkaz:
https://doaj.org/article/34f90e512d3b44eca2bdc200b388fb37
Autor:
Sophia M Blake, Stefan H Stricker, Hanna Halavach, Anna R Poetsch, George Cresswell, Gavin Kelly, Nnennaya Kanu, Silvia Marino, Nicholas M Luscombe, Steven M Pollard, Axel Behrens
Publikováno v:
eLife, Vol 5 (2016)
Glioblastoma multiforme (GBM) is the most aggressive human primary brain cancer. Using a Trp53-deficient mouse model of GBM, we show that genetic inactivation of the Atm cofactor Atmin, which is dispensable for embryonic and adult neural development,
Externí odkaz:
https://doaj.org/article/073bb96623004e5382578e901c23c945
Autor:
Davide Danovi, Amos Folarin, Sabine Gogolok, Christine Ender, Ahmed M O Elbatsh, Pär G Engström, Stefan H Stricker, Sladjana Gagrica, Ana Georgian, Ding Yu, Kin Pong U, Kevin J Harvey, Patrizia Ferretti, Patrick J Paddison, Jane E Preston, N Joan Abbott, Paul Bertone, Austin Smith, Steven M Pollard
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77053 (2013)
Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare resp
Externí odkaz:
https://doaj.org/article/19166962924b408289d08b363d1c7682
Autor:
Martha V Koerner, Florian M Pauler, Quanah J Hudson, Federica Santoro, Anna Sawicka, Philipp M Guenzl, Stefan H Stricker, Yvonne M Schichl, Paulina A Latos, Ruth M Klement, Katarzyna E Warczok, Jacek Wojciechowski, Christian Seiser, Robert Kralovics, Denise P Barlow
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002540 (2012)
A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited chromosomes. In addition to being modified on maternally inherited chromosomes by a DNA meth
Externí odkaz:
https://doaj.org/article/101388fd6d6d45abbce01052c01e8d80
Publikováno v:
Current Opinion in Genetics & Development. 70:iii-v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0229a409739bef40da642617db1485c1
https://doi.org/10.1016/j.gde.2021.08.001
https://doi.org/10.1016/j.gde.2021.08.001
Autor:
Rosario Sanchez-Gonzalez, Christina Koupourtidou, Tjasa Lepko, Alessandro Zambusi, Klara Tereza Novoselc, Tamara Durovic, Sven Aschenbroich, Veronika Schwarz, Christopher T. Breunig, Hans Straka, Hagen B. Huttner, Martin Irmler, Johannes Beckers, Wolfgang Wurst, Andreas Zwergal, Tamas Schauer, Tobias Straub, Tim Czopka, Dietrich Trümbach, Magdalena Götz, Stefan H. Stricker, Jovica Ninkovic
Publikováno v:
Cells; Volume 11; Issue 3; Pages: 520
Cells 11(3), 520 (2022). doi:10.3390/cells11030520
Sanchez-gonzalez, R, Koupourtidou, C, Lepko, T, Zambusi, A, Novoselc, K T, Durovic, T, Aschenbroich, S, Schwarz, V, Breunig, C T, Straka, H, Huttner, H B, Irmler, M, Beckers, J, Wurst, W, Zwergal, A, Schauer, T, Straub, T, Czopka, T, Trümbach, D, Götz, M, Stricker, S H & Ninkovic, J 2022, ' Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain ', Cells, vol. 11, no. 3, 520 . https://doi.org/10.3390/cells11030520
Cells, Vol 11, Iss 520, p 520 (2022)
Cells 11:520 (2022)
Cells 11(3), 520 (2022). doi:10.3390/cells11030520
Sanchez-gonzalez, R, Koupourtidou, C, Lepko, T, Zambusi, A, Novoselc, K T, Durovic, T, Aschenbroich, S, Schwarz, V, Breunig, C T, Straka, H, Huttner, H B, Irmler, M, Beckers, J, Wurst, W, Zwergal, A, Schauer, T, Straub, T, Czopka, T, Trümbach, D, Götz, M, Stricker, S H & Ninkovic, J 2022, ' Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain ', Cells, vol. 11, no. 3, 520 . https://doi.org/10.3390/cells11030520
Cells, Vol 11, Iss 520, p 520 (2022)
Cells 11:520 (2022)
The oligodendrocyte progenitors (OPCs) are at the front of the glial reaction to the traumatic brain injury. However, regulatory pathways steering the OPC reaction as well as the role of reactive OPCs remain largely unknown. Here, we compared a long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea31fe2ee460622cea941e6e7288006
Autor:
Valentin Baumann, Andrea M. Neuner, Christopher T. Breunig, Anna Köferle, Maximilian F. Wiesbeck, Stefan H. Stricker
Publikováno v:
Physiol. Rev. 101, 177-211 (2021)
Given the large amount of genome-wide data that have been collected during the last decades, a good understanding of how and why cells change during development, homeostasis, and disease might be expected. Unfortunately, the opposite is true; trigger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e9641f80e9e6a519c6804c78dec8be
https://pubmed.ncbi.nlm.nih.gov/32525760
https://pubmed.ncbi.nlm.nih.gov/32525760
Autor:
Stefan H. Stricker, Valentin Baumann
Publikováno v:
Stem Cell Investig. 6:30 (2019)
Comprehensive identification of factors that can specify neuronal fate could provide valuable insights into lineage specification and reprogramming, but systematic interrogation of transcription factors, and their interactions with each other, has pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5225ba4c796ff55942ca10fe75fe51b
https://europepmc.org/articles/PMC6789299/
https://europepmc.org/articles/PMC6789299/
Autor:
Giovanna Sonsalla, Christopher T. Breunig, Jessica Giehrl-Schwab, Magdalena Götz, Juliane Merl-Pham, Florian Giesert, Hans Zischka, Sabine Schmitt, Wolfgang Wurst, Gianluca Luigi Russo, Martin Jastroch, Stefan H. Stricker, Stefanie M. Hauck, Poornemaa Natarajan, Giacomo Masserdotti, Giorgia Bulli
Publikováno v:
Cell Stem Cell
Cell Stem Cell 28, 524-534.e7 (2021)
Cell stem cell 28(3), 524-534.e7 (2021). doi:10.1016/j.stem.2020.10.015
Cell Stem Cell 28, 524-534.e7 (2021)
Cell stem cell 28(3), 524-534.e7 (2021). doi:10.1016/j.stem.2020.10.015
Summary Astrocyte-to-neuron conversion is a promising avenue for neuronal replacement therapy. Neurons are particularly dependent on mitochondrial function, but how well mitochondria adapt to the new fate is unknown. Here, we determined the comprehen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8b14cf274b565ef82cd6dd243d979c
https://pubmed.ncbi.nlm.nih.gov/33667363
https://pubmed.ncbi.nlm.nih.gov/33667363