Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stefan Hümmer"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011316 (2024)
Splicing is an important step of gene expression regulation in eukaryotes, as there are many mRNA precursors that can be alternatively spliced in different tissues, at different cell cycle phases or under different external stimuli. We have developed
Externí odkaz:
https://doaj.org/article/cbcaa6af37cf4fb8a79967a589a13e90
Autor:
Pedro Fuentes, Marta Sesé, Pedro J. Guijarro, Marta Emperador, Sara Sánchez-Redondo, Héctor Peinado, Stefan Hümmer, Santiago Ramón y Cajal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for
Externí odkaz:
https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e010
Autor:
Cinthia Aguilera, Stefan Hümmer, Marc Masanas, Elisabeth Gabau, Miriam Guitart, A. Arockia Jeyaprakash, Miguel F. Segura, Anna Santamaria, Anna Ruiz
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
KIF1A is a microtubule-dependent motor protein responsible for fast anterograde transport of synaptic vesicle precursors in neurons. Pathogenic variants in KIF1A have been associated with a wide spectrum of neurological disorders. Here, we report a p
Externí odkaz:
https://doaj.org/article/a076fd12eddd46a3a646d90898b8af95
Autor:
Ana Martín-Pardillos, Ángeles Valls Chiva, Gemma Bande Vargas, Pablo Hurtado Blanco, Roberto Piñeiro Cid, Pedro J. Guijarro, Stefan Hümmer, Eva Bejar Serrano, Aitor Rodriguez-Casanova, Ángel Diaz-Lagares, Josep Castellvi, Samuel Miravet-Verde, Luis Serrano, María Lluch-Senar, Víctor Sebastian, Ana Bribian, Laura López-Mascaraque, Rafael López-López, Santiago Ramón y Cajal
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-26 (2019)
Abstract Background Cancer is a rapidly evolving, multifactorial disease that accumulates numerous genetic and epigenetic alterations. This results in molecular and phenotypic heterogeneity within the tumor, the complexity of which is further amplifi
Externí odkaz:
https://doaj.org/article/ae4d1b255d0540ae8d2c501bbcc4b97b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12444 (2021)
Pre-mRNA splicing is a major process in the regulated expression of genes in eukaryotes, and alternative splicing is used to generate different proteins from the same coding gene. Splicing is a catalytic process that removes introns and ligates exons
Externí odkaz:
https://doaj.org/article/a300f0c97a5e4738be753ebb9b31893b
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Intercellular communication is essential for the development of specialized cells, tissues, and organs and is critical in a variety of diseases including cancer. Current knowledge states that different cell types communicate by ligand–receptor inte
Externí odkaz:
https://doaj.org/article/7cd331d0b6a5401f83ee32f3c8ebf8ba
Autor:
Pedro Fuentes, Marta Sesé, Pedro J. Guijarro, Marta Emperador, Sara Sánchez-Redondo, Héctor Peinado, Stefan Hümmer, Santiago Ramón y Cajal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/6d1b8fa4e85e46778d8b5342f0a3705b
Autor:
Elisabeth Bou-Petit, Stefan Hümmer, Helena Alarcon, Konstantin Slobodnyuk, Marta Cano-Galietero, Pedro Fuentes, Pedro J. Guijarro, María José Muñoz, Leticia Suarez-Cabrera, Anna Santamaria, Roger Estrada-Tejedor, José I. Borrell, Santiago Ramón y Cajal
Publikováno v:
Scientia
Inhibidor de MNK1; Oncología Inhibidor de MNK1; Oncologia MNK1 inhibitor; Oncology Targeting the kinases MNK1 and MNK2 has emerged as a valuable strategy in oncology. However, most of the advanced inhibitors are acting in an adenosine triphosphate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471385260f1808040cbbd799dafcaa7e
https://hdl.handle.net/11351/8902
https://hdl.handle.net/11351/8902
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12444, p 12444 (2021)
Scientia
International Journal of Molecular Sciences
Scientia
International Journal of Molecular Sciences
Unión exón-intrón; Espliceosoma; Empalme Unió exó-intró; Spliceosoma; Empalme Exon-intron junction; Spliceosome; Splicing Pre-mRNA splicing is a major process in the regulated expression of genes in eukaryotes, and alternative splicing is used
Autor:
Santiago Ramón-Cajal, Stefan Hümmer
Publikováno v:
ANALES RANM. 135:230-236