CyBy2: a strongly typed, purely functional framework for chemical data management

Autor: Stefan Höck, Rainer Riedl

Publikováno v: Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-16 (2019)

Abstract We present the development of CyBy 2 , a versatile framework for chemical data management written in purely functional style in Scala, a modern multi-paradigm programming language. Together with the core libraries we provide a fully function

Externí odkaz: https://doaj.org/article/a02e3a722bb940f1aeff3db7ed8bdbcc

Thermal Cleavage of the Fmoc Protection Group

Autor: Stefan Höck, Roger Marti, Rainer Riedl, Marina Simeunovic

Publikováno v: CHIMIA, Vol 64, Iss 3 (2010)

The Fmoc protection group is among the most commonly used protection groups for the amino function. A fast method for the thermal deavage of this protection group under base-free conditions without the need for dibenzofulvene scavengers is presented.

Externí odkaz: https://doaj.org/article/73a6c7ccb55a4a348a1d9fe66bfa689d

Uncertainty-aware deep learning for trustworthy prediction of long-term outcome after endovascular thrombectomy

Autor: Celia Martín Vicario, Dalia Rodríguez Salas, Andreas Maier, Stefan Hock, Joji Kuramatsu, Bernd Kallmuenzer, Florian Thamm, Oliver Taubmann, Hendrik Ditt, Stefan Schwab, Arnd Dörfler, Iris Muehlen

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract Acute ischemic stroke (AIS) is a leading global cause of mortality and morbidity. Improving long-term outcome predictions after thrombectomy can enhance treatment quality by supporting clinical decision-making. With the advent of interpretab

Externí odkaz: https://doaj.org/article/cbf2993154894763a0b9921fdb52f9ab

Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment

Autor: Stefan Höck, Susanne Rüfenacht, Stephan Christen, Wolfgang Thormann, Markus Hilty, Lukas J. Troxler, Silvio D. Brugger, Kathrin Mühlemann, Julien Furrer, Brigitte Morand, Rudolf Geyer, Pascal M. Frey

Publikováno v: Infection and immunity
Brugger, Silvio; Troxler, Lukas; Rüfenacht, Susanne; Frey, Pascal Marcel; Morand, Brigitte; Geyer, Rudolf; Mühlemann, Kathrin; Höck, Stefan; Thormann, Wolfgang; Furrer, Julien; Christen, Stephan; Hilty, Markus (2016). Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment. Infection and immunity, 84(11), pp. 3152-3160. American Society for Microbiology 10.1128/IAI.00474-16

Serotype 19A strains have emerged as a cause of invasive pneumococcal disease after the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7), and serotype 19A has now been included in the recent 13-valent vaccine (PCV13). Genetic analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e6b1b8fb914117a1b533492ebd1574

Prognostic Accuracy of CTP Summary Maps in Patients with Large Vessel Occlusive Stroke and Poor Revascularization after Mechanical Thrombectomy—Comparison of Three Automated Perfusion Software Applications

Autor: Iris Muehlen, Matthias Borutta, Gabriela Siedler, Tobias Engelhorn, Stefan Hock, Michael Knott, Philip Hoelter, Bastian Volbers, Stefan Schwab, Arnd Doerfler

Publikováno v: Tomography, Vol 8, Iss 3, Pp 1350-1362 (2022)

Background: Innovative automated perfusion software solutions offer support in the management of acute stroke by providing information about the infarct core and penumbra. While the performance of different software solutions has mainly been investig

Externí odkaz: https://doaj.org/article/abe39643a2dd4877b4d20951ab04b828