Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Stefan Günther"'
Autor:
Lisa M. Weiss, Timothy Warwick, Simonida Zehr, Stefan Günther, Sebastian Wolf, Tessa Schmachtel, Judit Izquierdo Ponce, Katalin Pálfi, Tom Teichmann, Alicia Schneider, Julia Stötzel, Stefan Knapp, Andreas Weigert, Rajkumar Savai, Michael A. Rieger, Thomas Oellerich, Ilka Wittig, James A. Oo, Ralf P. Brandes, Matthias S. Leisegang
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Monocytes, the circulating macrophage precursors, contribute to diseases like atherosclerosis and asthma. Long non-coding RNAs (lncRNAs) have been shown to modulate the phenotype and inflammatory capacity of monocytes. We previously discover
Externí odkaz:
https://doaj.org/article/c50c57443bee4f3687d6cf428848b958
Autor:
Yundong Peng, Jingjing Du, Rui Li, Stefan Günther, Nina Wettschureck, Stefan Offermanns, Yan Wang, Andre Schneider, Thomas Braun
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Multiple processes control quiescence of muscle stem cells (MuSCs), which is instrumental to guarantee long-term replenishment of the stem cell pool. Here, we describe that the G-proteins G12-G13 integrate signals from different G-protein-co
Externí odkaz:
https://doaj.org/article/790430c2ddc44d10ac100c9cea1ebd1b
Autor:
João Cardeira-da-Silva, Qianchen Wang, Pooja Sagvekar, Janita Mintcheva, Stephan Latting, Stefan Günther, Radhan Ramadass, Michail Yekelchyk, Jens Preussner, Mario Looso, Jan Philipp Junker, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract In contrast to adult mammals, adult zebrafish can fully regenerate injured cardiac tissue, and this regeneration process requires an adequate and tightly controlled immune response. However, which components of the immune response are requir
Externí odkaz:
https://doaj.org/article/5d1f445d3f7a43f69b32b517875250bd
Autor:
Ursula Just, Helmut Burtscher, Sylvia Jeratsch, Meike Fischer, Carol Stocking, Jens Preussner, Mario Looso, Ralf Schwanbeck, Stefan Günther, Ralf Huss, Lynne Mullen, Thomas Braun
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0295641 (2024)
Brain metastasis leads to increased mortality and is a major site of relapse for several cancers, yet the molecular mechanisms of brain metastasis are not well understood. In this study, we established and characterized a new leukemic cell line, FIA1
Externí odkaz:
https://doaj.org/article/f912bd85dff741eba0d373a552e219bb
Autor:
Andrés Alberro-Brage, Vitalii Kryvenko, Christina Malainou, Stefan Günther, Rory E. Morty, Werner Seeger, Susanne Herold, Christos Samakovlis, István Vadász
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAcute respiratory distress syndrome (ARDS) is a common complication of influenza virus (IV) infection. During ARDS, alveolar protein concentrations often reach 40-90% of plasma levels, causing severe impairment of gas exchange and promoti
Externí odkaz:
https://doaj.org/article/b7e9f5d859bc4b569f48772fd4c2650d
Autor:
Ting Zhang, Carsten Künne, Dong Ding, Stefan Günther, Xinyue Guo, Yonggang Zhou, Xuejun Yuan, Thomas Braun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Suppression of transcription in S-phase is crucial to prevent genome instability. Zhang et al demonstrate that increase of H4K20me1 due to loss of Kmt5b cause genome instability in muscle stem cells, resulting in stem cell senescence but rhabdomyosar
Externí odkaz:
https://doaj.org/article/982571b2a822471e9f636df997aab30d
Autor:
Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski, James A. Oo, Nina M. Krause, Chao-Chung Kuo, Stefan Günther, Nevcin Sentürk Cetin, Timothy Warwick, Can Cao, Frederike Boos, Judit Izquierdo Ponce, Shaza Haydar, Rebecca Bednarz, Chanil Valasarajan, Dominik C. Fuhrmann, Jens Preussner, Mario Looso, Soni S. Pullamsetti, Marcel H. Schulz, Hendrik R. A. Jonker, Christian Richter, Flávia Rezende, Ralf Gilsbach, Beatrice Pflüger-Müller, Ilka Wittig, Ingrid Grummt, Teodora Ribarska, Ivan G. Costa, Harald Schwalbe, Ralf P. Brandes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Using a composite bioinformatics approach, the DNA:DNA:RNA triplex-forming lncRNAs HIF1α-AS1 was identified in human endothelial cells which recruits an epigenetic silencing complex to limit expression of triplex target genes.
Externí odkaz:
https://doaj.org/article/c3f7ecd225714cd98fa4bafc76a4baa2
Autor:
Andreas Weigert, Xiang Zheng, Alina Nenzel, Kati Turkowski, Stefan Günther, Elisabeth Strack, Evelyn Sirait-Fischer, Eiman Elwakeel, Ivan M. Kur, Vandana S. Nikam, Chanil Valasarajan, Hauke Winter, Alexander Wissgott, Robert Voswinkel, Friedrich Grimminger, Bernhard Brüne, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Fibrocytes are monocyte-derived cells implicated in wound healing. Here, the authors utilise single cell RNA-seq, genetic ablation and multiplexed imaging to identify a fibrocyte population in lung cancer models, and use human lung cancer coculture s
Externí odkaz:
https://doaj.org/article/a45ef476278744d49bbf2334b639d6fb
Autor:
Jitendriya Swain, Peggy Merida, Karla Rubio, David Bracquemond, Aymeric Neyret, Israel Aguilar-Ordoñez, Stefan Günther, Guillermo Barreto, Delphine Muriaux
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107384- (2023)
Summary: Our study focused on deciphering the role of F-actin and related regulatory factors during SARS-CoV-2 particle production and transmission in human pulmonary cells. Quantitative high-resolution microscopies revealed that the late phases of S
Externí odkaz:
https://doaj.org/article/7d1c266373404a13b15d2fc0522f4bfb
Autor:
Simon P. Pfäffle, Corinna Herz, Eva Brombacher, Michele Proietti, Michael Gigl, Christoph K. Hofstetter, Verena K. Mittermeier-Kleßinger, Sophie Claßen, Hoai T. T. Tran, Corinna Dawid, Clemens Kreutz, Stefan Günther, Evelyn Lamy
Publikováno v:
Nutrients, Vol 16, Iss 3, p 373 (2024)
Despite substantial heterogeneity of studies, there is evidence that antibiotics commonly used in primary care influence the composition of the gastrointestinal microbiota in terms of changing their composition and/or diversity. Benzyl isothiocyanate
Externí odkaz:
https://doaj.org/article/e4443df620ef45e78cb19551e23747d7