Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Stefan Giselbrecht"'
Publikováno v:
Advanced Science, Vol 11, Iss 4, Pp n/a-n/a (2024)
Abstract Combining high‐throughput generation and high‐content imaging of embryo models will enable large‐scale screening assays in the fields of (embryo) toxicity, drug development, embryogenesis, and reproductive medicine. This study shows th
Externí odkaz:
https://doaj.org/article/f128aaf29e7d4d41aa0dd0dc6ff2bfe5
Autor:
Cas van der Putten, Gozde Sahin, Rhiannon Grant, Mirko D’Urso, Stefan Giselbrecht, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 402 (2024)
In the event of disease or injury, restoration of the native organization of cells and extracellular matrix is crucial for regaining tissue functionality. In the cornea, a highly organized collagenous tissue, keratocytes can align along the anisotrop
Externí odkaz:
https://doaj.org/article/8b5f5e14ad0645b0908cea1b34f7b7f6
Autor:
Steven Vermeulen, Kèvin Knoops, Hans Duimel, Maryam Parvizifard, Denis van Beurden, Carmen López-Iglesias, Stefan Giselbrecht, Roman Truckenmüller, Pamela Habibović, Zeinab Tahmasebi Birgani
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100844- (2023)
A challenge in regenerative medicine is creating the three-dimensional organic and inorganic in vitro microenvironment of bone, which would allow the study of musculoskeletal disorders and the generation of building blocks for bone regeneration. This
Externí odkaz:
https://doaj.org/article/b063838695a64f8a9f2b2869700de350
Autor:
Pinak Samal, Jay Rabindra Kumar Samal, Hoon Suk Rho, Denis van Beurden, Clemens van Blitterswijk, Roman Truckenmüller, Stefan Giselbrecht
Publikováno v:
Materials Today Bio, Vol 22, Iss , Pp 100779- (2023)
Microengineering is increasingly being used for controlling the microenvironment of stem cells. Here, a novel method for fabricating structures with subcellular dimensions in commonly available thermoplastic poly(methyl methacrylate) (PMMA) is shown.
Externí odkaz:
https://doaj.org/article/95eab6a8cb11412b86ec98441e44bbaf
Autor:
Marta Nazzari, Mírian Romitti, Duncan Hauser, Daniel J. Carvalho, Stefan Giselbrecht, Lorenzo Moroni, Sabine Costagliola, Florian Caiment
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPhthalates are a class of endocrine-disrupting chemicals that have been shown to negatively correlate with thyroid hormone serum levels in humans and to cause a state of hyperactivity in the thyroid. However, their mechanism of action is
Externí odkaz:
https://doaj.org/article/f80f4a1b347941bab93a8d7debdae782
Autor:
Danielle Baptista, Zeinab Tahmasebi Birgani, Helene Widowski, Fiona Passanha, Vasili Stylianidis, Kèvin Knoops, Eva Gubbins, Cinta Iriondo, Kari-Pekka Skarp, Robbert J. Rottier, Tim G. Wolfs, Clemens van Blitterswijk, Vanessa LaPointe, Pamela Habibović, Niki L. Reynaert, Stefan Giselbrecht, Roman Truckenmüller
Publikováno v:
Materials Today Bio, Vol 19, Iss , Pp 100603- (2023)
The culture of lung organoids relies on drops of basement membrane matrices. This comes with limitations, for example, concerning the microscopic monitoring and imaging of the organoids in the drops. Also, the culture technique is not easily compatib
Externí odkaz:
https://doaj.org/article/d7c7a790a5b44159bbbc8155fb72fba8
Autor:
Panagiota Kakni, Barry Jutten, Daniel Teixeira Oliveira Carvalho, John Penders, Roman Truckenmüller, Pamela Habibovic, Stefan Giselbrecht
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Microbiome is an integral part of the gut and is essential for its proper function. Imbalances of the microbiota can be devastating and have been linked with several gastrointestinal conditions. Current gastrointestinal models do not fully reflect th
Externí odkaz:
https://doaj.org/article/d858ae42caed482ab23f36fd2c9148b7
Autor:
Panagiota Kakni, Carmen López-Iglesias, Roman Truckenmüller, Pamela Habibović, Stefan Giselbrecht
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Intestinal organoids recapitulate many features of the in vivo gastrointestinal tract and have revolutionized in vitro studies of intestinal function and disease. However, the restricted accessibility of the apical surface of the organoids facing the
Externí odkaz:
https://doaj.org/article/d1e4932f6dfb4da3813f6542d3b0aefe
Autor:
Andrea Romano, Sun-Wei Guo, Jan Brosens, Asgerally Fazlebas, Caroline E Gargett, Stefan Giselbrecht, Martin Gotte, Linda Griffith, Hugh S Taylor, Robert N Taylor, Hugo Vankelecom, Charles Chapron, Xiao-Hong Chang, Khaleque N Khan, Paola Vigano
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 3, Pp G1-G8 (2022)
In vitro culturing of endometrial cells obtained from the uterine mucosa or ectopic sites is used to study molecular and cellular signalling relevant to physiologic and pathologic reproductive conditions. However, the lack of consensus on standard op
Externí odkaz:
https://doaj.org/article/08bdf768b4204bce9ad6f1c86dae5128
Autor:
Aysegul Dede Eren, Amy W. A. Lucassen, Urandelger Tuvshindorj, Roman Truckenmüller, Stefan Giselbrecht, E. Deniz Eren, Mehmet Orhan Tas, Phanikrishna Sudarsanam, Jan de Boer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cells probe their environment and adapt their shape accordingly via the organization of focal adhesions and the actin cytoskeleton. In an earlier publication, we described the relationship between cell shape and physiology, for example, shape-induced
Externí odkaz:
https://doaj.org/article/19d8fe21b38142fa8525b6feaa9e7d7d