Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Stefan Gaubatz"'
Autor:
Marco Gründl, Susanne Walz, Laura Hauf, Melissa Schwab, Kerstin Marcela Werner, Susanne Spahr, Clemens Schulte, Hans Michael Maric, Carsten P Ade, Stefan Gaubatz
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008818 (2020)
The Hippo signalling pathway and its central effector YAP regulate proliferation of cardiomyocytes and growth of the heart. Using genetic models in mice we show that the increased proliferation of embryonal and postnatal cardiomyocytes due to loss of
Externí odkaz:
https://doaj.org/article/068d2290b6684263b21146abde8f3e0a
Autor:
Grit Weinstock, Stefan Gaubatz
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 6 (2019)
The Hippo pathway plays a major role in regulating organ size during embryogenesis. Loss of Hippo signaling can cause cancer due to unrestricted cell proliferation. Recently we found that Yes-associated protein 1 (YAP1), the major downstream effector
Externí odkaz:
https://doaj.org/article/78d60793daa8443db90999f492bb749b
Autor:
Grit Pattschull, Susanne Walz, Marco Gründl, Melissa Schwab, Eva Rühl, Apoorva Baluapuri, Anita Cindric-Vranesic, Susanne Kneitz, Elmar Wolf, Carsten P. Ade, Andreas Rosenwald, Björn von Eyss, Stefan Gaubatz
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3533-3546.e7 (2019)
Summary: YAP and TAZ, downstream effectors of the Hippo pathway, are important regulators of proliferation. Here, we show that the ability of YAP to activate mitotic gene expression is dependent on the Myb-MuvB (MMB) complex, a master regulator of ge
Externí odkaz:
https://doaj.org/article/c8b9040b38cd47f79ad6523a968695d8
Autor:
Jasmina Esterlechner, Nina Reichert, Fabian Iltzsche, Michael Krause, Florian Finkernagel, Stefan Gaubatz
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62882 (2013)
The DREAM complex plays an important role in regulation of gene expression during the cell cycle. We have previously shown that the DREAM subunit LIN9 is required for early embryonic development and for the maintenance of the inner cell mass in vitro
Externí odkaz:
https://doaj.org/article/93b0fa280191495e832c50b4056b0e6d
Publikováno v:
Cell Cycle. 22:419-432
Protein regulator of cytokinesis 1 (PRC1) is a microtubule-binding protein with essential roles in mitosis and cytokinesis. PRC1 is frequently overexpressed in cancer cells where it could contribute to chromosomal instability. Due to its nuclear loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b9f2e9cbc800fbbdbaa1bd952a4c95
https://doi.org/10.1080/15384101.2022.2122258
https://doi.org/10.1080/15384101.2022.2122258
Autor:
Felix B. Engel, Stefan Gaubatz, Marcus Krüger, Markus Eckstein, Silvia Vergarajauregui, Grit Weinstock, Marco Gründl, Janica L. Wiederstein, Fulvia Ferrazzi, Salvador Cazorla-Vázquez, Marina Leone
HeLa cell stably expressing α-tubulin tagged with mCherry overexpressing IQGAP3 tagged with GFP (late anaphase/telophase to cytokinesis).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5fe252d92f55c6ff03468f742c2ea1
https://doi.org/10.1158/1541-7786.22526291
https://doi.org/10.1158/1541-7786.22526291
Autor:
Felix B. Engel, Stefan Gaubatz, Marcus Krüger, Markus Eckstein, Silvia Vergarajauregui, Grit Weinstock, Marco Gründl, Janica L. Wiederstein, Fulvia Ferrazzi, Salvador Cazorla-Vázquez, Marina Leone
IQGAP3 expression in human cervical cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ba5bbef4a6ea0b56a357710c14ecb1
https://doi.org/10.1158/1541-7786.22526276.v1
https://doi.org/10.1158/1541-7786.22526276.v1
Autor:
Felix B. Engel, Stefan Gaubatz, Marcus Krüger, Markus Eckstein, Silvia Vergarajauregui, Grit Weinstock, Marco Gründl, Janica L. Wiederstein, Fulvia Ferrazzi, Salvador Cazorla-Vázquez, Marina Leone
HeLa cell stably transfected with mCherry-α-tubulin transfected with siIQ3#1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680aa85842b6432508525120e1dedcfd
https://doi.org/10.1158/1541-7786.22526294
https://doi.org/10.1158/1541-7786.22526294
Autor:
Felix B. Engel, Stefan Gaubatz, Marcus Krüger, Markus Eckstein, Silvia Vergarajauregui, Grit Weinstock, Marco Gründl, Janica L. Wiederstein, Fulvia Ferrazzi, Salvador Cazorla-Vázquez, Marina Leone
Controlling cell proliferation is critical for organism development, tissue homeostasis, disease, and regeneration. IQGAP3 has been shown to be required for proper cell proliferation and migration, and is associated to a number of cancers. Moreover,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a213471ee953f11172d40c5c512acb1
https://doi.org/10.1158/1541-7786.c.6545051.v1
https://doi.org/10.1158/1541-7786.c.6545051.v1
Autor:
Felix B. Engel, Stefan Gaubatz, Marcus Krüger, Markus Eckstein, Silvia Vergarajauregui, Grit Weinstock, Marco Gründl, Janica L. Wiederstein, Fulvia Ferrazzi, Salvador Cazorla-Vázquez, Marina Leone
HeLa cell stably transfected with mCherry-α-tubulin transfected with siCtrl.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25561f6fbf037208f175f1f11382594f
https://doi.org/10.1158/1541-7786.22526297
https://doi.org/10.1158/1541-7786.22526297