Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stefan Foser"'
Autor:
Rekha Badiger, Jane A Mitchell, Hime Gashaw, Neil A Galloway-Phillipps, Stefan Foser, Fernando Tatsch, Thomas Singer, Trevor T Hansel, Tobias Manigold
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46779 (2012)
Alfa-interferons (IFNα2a, IFNα2b, 40KDa-PEGIFNα2a and 12KDa-PEGIFNα2b) are effective treatments for chronic hepatitis C infection. However, their usage has been associated with a variety of adverse events, including interstitial pneumonitis and p
Externí odkaz:
https://doaj.org/article/8b3d9158413b4a5190c0cfc5b2c0d180
Autor:
Georgios Pentheroudakis, Stefan Foser, George Zarkavelis, Tilmann Bochtler, Andreas Beringer, Mustafa Ozguroglu, Chantal Pauli, Ferran Losa, M. Mueller-Ohldach, Alwin Krämer, J.S. Ross, J. Scarato, Holger Moch, Giulia Baciarello, Linda Mileshkin, S Songül Yalçin
Publikováno v:
Publons
Background The CUPISCO trial (NCT03498521) is an ongoing, phase II, randomised, multicentre study comparing molecularly-guided therapy with standard platinum-based chemotherapy in newly diagnosed poor-risk CUP patients. Methods Eligible patients have
Autor:
Stefan Foser, C. Mascaux, Kieran Mace, James W. Clendening, Lisa I. Wang, Luis Paz-Ares, Lukas Bubendorf, Q. Zhang, Adam Gondos, Fabrice Barlesi
Publikováno v:
Journal of Clinical Oncology. 37:9076-9076
9076 Background: The number of targeted txs for NSCLC is increasing. By analyzing numerous molecular alterations, CGP may open more targeted tx options than single biomarker testing. Methods: We analyzed a database linking Flatiron Health electronic
Autor:
Alwin Krämer, Ferran Losa, Laurie M. Gay, Ethan Sokol, Damian R. Page, Garrett Michael Frampton, Stefan Foser, Tariq I. Mughal, Jeffrey S. Ross, Giulia Baciarello, Linda R. Mileshkin, Holger Moch
Publikováno v:
Journal of Clinical Oncology. 36:e24162-e24162
e24162Background: CUP represents a wide range of heterogeneous tumors with diverse genomic alterations (GAs) and high unmet clinical need. Molecular profiling of gene panels at diagnosis is increas...
Autor:
Francis Müller, Alfred Ross, Stefan Foser, Luc-Alexis Leuthold, Hans Martin Senn, Bernard Gsell, Christophe Dhalluin
Publikováno v:
Bioconjugate Chemistry. 16:504-517
The human recombinant Interferon-alpha(2a) (IFNalpha(2a)) is a potent drug (Roferon-A) to treat various types of cancer and viral diseases including Hepatitis B/C infections. To improve the pharmacological properties of the drug, a new pegylated form
Publikováno v:
Thrombosis and Haemostasis. 94:347-361
SummaryThe bacterial pathogen Bartonella henselae (Bh) is for respona sible broad range of clinical manifestations, including the formation of vascular tumours as the result of pathogen-triggered vasoproliferation. In vitro, the interaction of Bh wit
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 31(8)
The interferon (IFN)-α response gene interferon-induced transmembrane protein 3 (IFITM3) has antiproliferative properties in a number of biological systems. In the human melanoma cell line D10, IFITM3 is constitutively expressed and we show that the
Autor:
Martin Ebeling, Bernd Bohrmann, Y. Burki, L.C. Hallen, C. Broger, Krisztina Oroszlan-Szovik, Fredy Siegrist, Ulrich Certa, Stefan Foser
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 27(8)
The interferon-alpha (IFN-alpha)-inducible protein IFI44 is associated with hepatitis C virus (HCV) infection, and its function is unknown. We show here in two human melanoma cell lines (ME15 and D10) that transcription starts 4 h after induction, an
Autor:
Christophe, Dhalluin, Alfred, Ross, Luc-Alexis, Leuthold, Stefan, Foser, Bernard, Gsell, Francis, Müller, Hans, Senn
Publikováno v:
Bioconjugate chemistry. 16(3)
The human recombinant Interferon-alpha(2a) (IFNalpha(2a)) is a potent drug (Roferon-A) to treat various types of cancer and viral diseases including Hepatitis B/C infections. To improve the pharmacological properties of the drug, a new pegylated form
Publikováno v:
The pharmacogenomics journal. 3(6)
The addition of polyethyleneglycol (PEG) side chains to interferon alpha-2a improves the serum stability and clinical efficacy. Current commercial PEG-INF formulations such as PEGASYS are heterogeneous and contain multiple monopegylated isomers. We h