Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Stefan Enroth"'
Autor:
Emma Ivansson, Julia Hedlund Lindberg, Karin Stålberg, Karin Sundfeldt, Ulf Gyllensten, Stefan Enroth
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Ovarian cancer is the 8th most common cancer among women and has a 5-year survival of only 30–50%. While the survival is close to 90% for stage I tumours it is only 20% for stage IV. Current biomarkers are not sensitive nor specific enough
Externí odkaz:
https://doaj.org/article/25b468e7601b4085bdac64b08aadb021
Autor:
Julia Hedlund Lindberg, Anna Widgren, Emma Ivansson, Inger Gustavsson, Karin Stålberg, Ulf Gyllensten, Karin Sundfeldt, Jonas Bergquist, Stefan Enroth
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109001- (2024)
Summary: Early detection is key for increased survival in ovarian cancer, but no general screening program exists today due to lack of biomarkers and overall cost versus benefit over traditional clinical methods. Here, we used dried cervico-vaginal f
Externí odkaz:
https://doaj.org/article/9216e809903b445ca51db82f08bd1651
Autor:
Stefan Enroth, Emma Ivansson, Julia Hedlund Lindberg, Maria Lycke, Jessica Bergman, Anna Reneland, Karin Stålberg, Karin Sundfeldt, Ulf Gyllensten
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-13 (2022)
Enroth et al. validate their previously developed 11-biomarker plasma protein-based risk-score for distinguishing benign vs. malignant ovarian tumors. The risk score is found to be informative of treatment outcome and predictive of 5-year survival.
Externí odkaz:
https://doaj.org/article/f535e2e5697b4fbe93be405fe600836d
Autor:
Philip C. Haycock, Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaitre, Stephen Burgess, Nikhil K. Khankari, Konstantinos K. Tsilidis, Tom R. Gaunt, Gibran Hemani, Jie Zheng, Therese Truong, Brenda M. Birmann, Tracy OMara, Amanda B. Spurdle, Mark M. Iles, Matthew H. Law, Susan L. Slager, Fatemeh Saberi Hosnijeh, Daniela Mariosa, Michelle Cotterchio, James R. Cerhan, Ulrike Peters, Stefan Enroth, Puya Gharahkhani, Loic Le Marchand, Ann C. Williams, Robert C. Block, Christopher I. Amos, Rayjean J. Hung, Wei Zheng, Marc J. Gunter, George Davey Smith, Caroline Relton, Richard M. Martin, Nathan Tintle, Terri Rice, Iona Cheng, Mark Jenkins, Steve Gallinger, Alex J. Cornish, Amit Sud, Jayaram Vijayakrishnan, Margaret Wrensch, Mattias Johansson, Aaron D. Norman, Alison Klein, Alyssa Clay-Gilmour, Andre Franke, Andres V. Ardisson Korat, Bill Wheeler, Björn Nilsson, Caren Smith, Chew-Kiat Heng, Ci Song, David Riadi, Elizabeth B. Claus, Eva Ellinghaus, Evgenia Ostroumova, Hosnijeh, Florent de Vathaire, Giovanni Cugliari, Giuseppe Matullo, Irene Oi-Lin Ng, Jeanette E. Passow, Jia Nee Foo, Jiali Han, Jianjun Liu, Jill Barnholtz-Sloan, Joellen M. Schildkraut, John Maris, Joseph L. Wiemels, Kari Hemminki, Keming Yang, Lambertus A. Kiemeney, Lang Wu, Laufey Amundadottir, Marc-Henri Stern, Marie-Christine Boutron, Mark Martin Iles, Mark P. Purdue, Martin Stanulla, Melissa Bondy, Mia Gaudet, Lenha Mobuchon, Nicola J. Camp, Pak Chung Sham, Pascal Guénel, Paul Brennan, Philip R. Taylor, Quinn Ostrom, Rachael Stolzenberg-Solomon, Rajkumar Dorajoo, Richard Houlston, Robert B. Jenkins, Sharon Diskin, Sonja I. Berndt, Spiridon Tsavachidis, Stephen J. Channock, Tabitha Harrison, Tessel Galesloot, Ulf Gyllensten, Vijai Joseph, Y. Shi, Wenjian Yang, Yi Lin, Stephen K. Van Den Eeden
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104510- (2023)
Summary: Background: The causal relevance of polyunsaturated fatty acids (PUFAs) for risk of site-specific cancers remains uncertain. Methods: Using a Mendelian randomization (MR) framework, we assessed the causal relevance of PUFAs for risk of cance
Externí odkaz:
https://doaj.org/article/89940d7363ce43c781ea8d5c3c0a79fa
Autor:
Marcin Kierczak, Nima Rafati, Julia Höglund, Hadrien Gourlé, Valeria Lo Faro, Daniel Schmitz, Weronica E. Ek, Ulf Gyllensten, Stefan Enroth, Diana Ekman, Björn Nystedt, Torgny Karlsson, Åsa Johansson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Despite the success of genome-wide association studies, much of the genetic contribution to complex traits remains unexplained. Here, the authors identify effects by rare variants on plasma proteins, and estimate the contribution of rare variants to
Externí odkaz:
https://doaj.org/article/1070fe1cf0884dc9a1fe9d7ebf5b6af9
Autor:
Malin Berggrund, Inger Gustavsson, Riina Aarnio, Julia Hedlund Lindberg, Karin Sanner, Ingrid Wikström, Stefan Enroth, Ignas Bunikis, Matts Olovsson, Ulf Gyllensten
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background The vaginal microbiota has been reported to be associated with HPV infection and cervical cancer. This study was performed to compare the vaginal microbiota at two timepoints in women performing self-sampling and had a persistent
Externí odkaz:
https://doaj.org/article/fdcacec767ab420e847436c6306a79f3
Publikováno v:
Environment International, Vol 152, Iss , Pp 106488- (2021)
Interactions between environmental factors and genetics underlie the majority of chronic human diseases. Chemical exposures are likely an underestimated contributor, yet gene-environment (GxE) interaction studies rarely assess their modifying effects
Externí odkaz:
https://doaj.org/article/6b2c9c9c922741ac9a0d603261ff9fb1
Autor:
Inger Gustavsson, Riina Aarnio, Mattias Myrnäs, Julia Hedlund-Lindberg, Ongeziwe Taku, Tracy Meiring, Ingrid Wikström, Stefan Enroth, Anna-Lise Williamson, Matts Olovsson, Ulf Gyllensten
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-7 (2019)
Abstract Background The indicating FTA card is a dry medium used for collection of cervical samples. HPVIR is a multiplex real-time PCR test that detects 12 high-risk human papillomavirus types (hrHPV) and provides single genotype information for HPV
Externí odkaz:
https://doaj.org/article/104dee633f154168beed62b7aa6e943d
Autor:
Stefan Enroth, Malin Berggrund, Maria Lycke, Martin Lundberg, Erika Assarsson, Matts Olovsson, Karin Stålberg, Karin Sundfeldt, Ulf Gyllensten
Publikováno v:
Clinical Proteomics, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Over 500,000 women worldwide are diagnosed with ovarian or endometrial cancer each year. We have used a two-step strategy to identify plasma proteins that could be used to improve the diagnosis of women with an indication of gynec
Externí odkaz:
https://doaj.org/article/6f008926d3774460b98cded9a4ff5a7c
Autor:
Ulf Gyllensten, Julia Hedlund-Lindberg, Johanna Svensson, Johanna Manninen, Torbjörn Öst, Jon Ramsell, Matilda Åslin, Emma Ivansson, Marta Lomnytska, Maria Lycke, Tomas Axelsson, Ulrika Liljedahl, Jessica Nordlund, Per-Henrik Edqvist, Tobias Sjöblom, Mathias Uhlén, Karin Stålberg, Karin Sundfeldt, Mikael Åberg, Stefan Enroth
Publikováno v:
Cancers, Vol 14, Iss 7, p 1757 (2022)
Background: Ovarian cancer is the eighth most common cancer among women and has a 5-year survival of only 30–50%. The survival is close to 90% for patients in stage I but only 20% for patients in stage IV. The presently available biomarkers have in
Externí odkaz:
https://doaj.org/article/08f12d2e4a4f4855a5aaff801f7d901a