Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Stefan E. Sonderegger"'
Autor:
Cedric S. Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E. Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M. Salmon, Adam McCluskey, Richard B. Lock, Phillip J. Robinson, Stephen M. Jane, David J. Curtis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The tumour microenvironment provides signals to support leukaemic stem cells (LSC) maintenance and chemoresistance. Here, the authors show that disrupting niche-associated signalling by inhibiting receptor-mediated endocytosis with a dynamin GTPase i
Externí odkaz:
https://doaj.org/article/9f9ae7f5fae34540a33d8cb9dbda1467
Autor:
Cedric S. Tremblay, Jesslyn Saw, Sung Kai Chiu, Nicholas C. Wong, Kirill Tsyganov, Sarah Ghotb, Alison N. Graham, Feng Yan, Andrew A. Guirguis, Stefan E. Sonderegger, Nicole Lee, Paul Kalitsis, John Reynolds, Stephen B. Ting, David R. Powell, Stephen M. Jane, David J. Curtis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cell cycle kinetics of pre-leukemic stem cells (pre-LSCs) may be an important determinant of clonal evolution and therapeutic resistance. Here, the AUs use a transgenic T-ALL mouse model that allows non-dividing cells to be tracked and identify a sub
Externí odkaz:
https://doaj.org/article/b35a3f8af939445d8e61e8a054430aae
Attenuated Acceleration to Leukemia after Ezh2 Loss in Nup98-HoxD13 (NHD13) Myelodysplastic Syndrome
Autor:
Victoria Y. Ling, Jesslyn Saw, Cedric S. Tremblay, Stefan E. Sonderegger, Emma Toulmin, Jacqueline Boyle, Sung Kai Chiu, Steven W. Lane, Stephen B. Ting, David J. Curtis
Publikováno v:
HemaSphere, Vol 3, Iss 4 (2019)
Externí odkaz:
https://doaj.org/article/a3b4749fb5ac4d3c8316268378a28849
Autor:
Cedric S. Tremblay, Sung Kai Chiu, Jesslyn Saw, Hannah McCalmont, Veronique Litalien, Jacqueline Boyle, Stefan E. Sonderegger, Ngoc Chau, Kathryn Evans, Loretta Cerruti, Jessica M. Salmon, Adam McCluskey, Richard B. Lock, Phillip J. Robinson, Stephen M. Jane, David J. Curtis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21688-1
Externí odkaz:
https://doaj.org/article/9846dc9e5dfd409a8bf2b3f5a56fc30d
Autor:
Fazrena Nadia Md Akhir, Mohd Hezmee Mohd Noor, Keith Weng Kit Leong, Jamileh A. Nabizadeh, Helga D. Manthey, Stefan E. Sonderegger, Jenny Nga Ting Fung, Crystal E. McGirr, Ian A. Shiels, Paul C. Mills, Trent M. Woodruff, Barbara E. Rolfe
Publikováno v:
Antibodies, Vol 10, Iss 1, p 2 (2021)
The complement system has demonstrated roles in regulating tumor growth, although these may differ between tumor types. The current study used two murine breast cancer models (EMT6 and 4T1) to investigate whether pharmacological targeting of receptor
Externí odkaz:
https://doaj.org/article/ed5826c8ab7746d6bb9209f09dfcb2ce
Autor:
Stefan E. Sonderegger, Silvia Manzanero, Trent M. Woodruff, Jad Farouqa, Jamileh Nabizadeh, Nadya Panagides, Barbara E. Rolfe
Publikováno v:
Clinical Immuno-Oncology ISBN: 9780323877633
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4c9aa489846300e672e2292da47622b
https://doi.org/10.1016/b978-0-323-87763-3.00012-5
https://doi.org/10.1016/b978-0-323-87763-3.00012-5
Autor:
Parul Agarwal, Vinod P. Balachandran, Challice L. Bonifant, Timothy N.J. Bullock, William R. Burns, Sophia Y. Chen, Daniel Delitto, Stephen Desiderio, Jad Farouqa, Maria J. Gutierrez, Thatcher R. Heumann, Hyun Min Jung, Silvia Manzanero, Jamileh Nabizadeh, John E. Niederhuber, Olamide Olayinka, Nadya Panagides, Luis A. Rojas, Barbara E. Rolfe, Melanie Rutkowski, Stefan E. Sonderegger, Brant M. Weinstein, Trent M. Woodruff, Lei Zheng
Publikováno v:
Clinical Immuno-Oncology ISBN: 9780323877633
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c877a5c679441bed02801a84120627b
https://doi.org/10.1016/b978-0-323-87763-3.00003-4
https://doi.org/10.1016/b978-0-323-87763-3.00003-4
Autor:
David Pizzi, James Humphries, Joshua P. Morrow, Ayaat M. Mahmoud, Nicholas L. Fletcher, Stefan E. Sonderegger, Craig A. Bell, Kristofer J. Thurecht, Kristian Kempe
Publikováno v:
Biomacromolecules. 24:246-257
Poly(2-oxazoline)s (POx) have received substantial attention as poly(ethylene glycol) (PEG) alternatives in the biomedical field due to their biocompatibility, high functionality, and ease of synthesis. While POx have demonstrated strong potential as
Autor:
Jessica A. Mills, James Humphries, Joshua D. Simpson, Stefan E. Sonderegger, Kristofer J. Thurecht, Nicholas L. Fletcher
Publikováno v:
Molecular pharmaceutics. 19(11)
Nanomedicines show benefits in overcoming the limitations of conventional drug delivery systems by reducing side effects, toxicity, and exhibiting enhanced pharmacokinetic (PK) profiles to improve the therapeutic window of small-molecule drugs. Howev
Autor:
Sung K, Chiu, Jesslyn, Saw, Yizhou, Huang, Stefan E, Sonderegger, Nicholas C, Wong, David R, Powell, Dominic, Beck, John E, Pimanda, Cedric S, Tremblay, David J, Curtis
Publikováno v:
Development (Cambridge, England). 145(19)
Stem cell leukemia (