Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Stefan Duhr"'
Autor:
Karolina Corin, Philipp Baaske, Deepali B Ravel, Junyao Song, Emily Brown, Xiaoqiang Wang, Sandra Geissler, Christoph J Wienken, Moran Jerabek-Willemsen, Stefan Duhr, Dieter Braun, Shuguang Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e23036 (2011)
Membrane proteins, particularly G-protein coupled receptors (GPCRs), are notoriously difficult to express. Using commercial E. coli cell-free systems with the detergent Brij-35, we could rapidly produce milligram quantities of 13 unique GPCRs. Immuno
Externí odkaz:
https://doaj.org/article/08442d96fbdd466ca1606d4e76038eda
Autor:
Karolina Corin, Philipp Baaske, Deepali B Ravel, Junyao Song, Emily Brown, Xiaoqiang Wang, Christoph J Wienken, Moran Jerabek-Willemsen, Stefan Duhr, Yuan Luo, Dieter Braun, Shuguang Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e25067 (2011)
A crucial bottleneck in membrane protein studies, particularly G-protein coupled receptors, is the notorious difficulty of finding an optimal detergent that can solubilize them and maintain their stability and function. Here we report rapid productio
Externí odkaz:
https://doaj.org/article/1b4d966cc2c14c76a1c8cf17b5b8e4f9
Autor:
Andreas Langer, Annemarie Lüdecke, Tanja Bartoschik, Ondrej Cehlar, Stefan Duhr, Philipp Baaske, Werner Streicher
Publikováno v:
ASSAY and Drug Development Technologies. 20:83-94
Publikováno v:
Annals of the V ISI.
Autor:
François Vallée, Philipp Baaske, Melanie Maschberger, Valerie Steier, Kwame Amaning, Pawel Linke, Stefan Duhr, Alexey Rak, Dennis Breitsprecher
Publikováno v:
Journal of Biomolecular Screening
Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that
Publikováno v:
Encyclopedia of Biophysics ISBN: 9783642359439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8cd3c9e6bcd09b4b688ba5df3fc25db
https://doi.org/10.1007/978-3-642-35943-9_10063-1
https://doi.org/10.1007/978-3-642-35943-9_10063-1
Autor:
Adrian Michael, Mueller, Dennis, Breitsprecher, Stefan, Duhr, Philipp, Baaske, Thomas, Schubert, Gernot, Längst
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1654
Interactions between nucleic acids and proteins are driving gene expression programs and regulating the development of organisms. The binding affinities of transcription factors to their target sites are essential parameters to reveal their binding s
Autor:
Stefan Duhr, Christopher M. Johnson, Gerhard Winter, Philipp Baaske, Dennis Breitsprecher, Neil M. Ferguson, Crispin G. Alexander, Randy Wanner
Publikováno v:
Biochimica et Biophysica Acta
Chemical denaturant titrations can be used to accurately determine protein stability. However, data acquisition is typically labour intensive, has low throughput and is difficult to automate. These factors, combined with high protein consumption, hav
Autor:
Moran Jerabek-Willemsen, Philipp Baaske, Randy Wanner, Stefan Duhr, Timon André, Dennis Breitsprecher, Heide Marie Roth
Publikováno v:
Journal of Molecular Structure. 1077:101-113
MicroScale Thermophoresis (MST) is a powerful technique to quantify biomolecular interactions. It is based on thermophoresis, the directed movement of molecules in a temperature gradient, which strongly depends on a variety of molecular properties su
Autor:
Philipp Baaske, Alessandra Feoli, Melanie Maschberger, Tanja Bartoschik, Stefan Duhr, Timon André, Dennis Breitsprecher
Publikováno v:
Applied Biophysics for Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27e13196d46d190afde0ca866e2407e
http://hdl.handle.net/11386/4700030
http://hdl.handle.net/11386/4700030