Zobrazeno 1 - 10
of 12 247
pro vyhledávání: '"Stefan D"'
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Liquid-liquid phase separation (LLPS) of proteins can be considered an intermediate solubility regime between disperse solutions and solid fibers. While LLPS has been described for several pathogenic amyloids, recent evidence suggests that i
Externí odkaz:
https://doaj.org/article/128ee40371c64d9c91f50032806bf69b
Autor:
Sahoko Takagi, Shosuke Satake, Ken Sugimoto, Masafumi Kuzuya, Masahiro Akishita, Hidenori Arai, Ivan Aprahamian, Andrew J. Coats, Tatiana Klompenhouwer, Stefan D. Anker, Hidetaka Wakabayashi
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 2164-2174 (2024)
Abstract Background Anorexia of aging (AA) is a condition in older adults that includes loss of appetite and reduced food intake. There is a lack of detailed analysis of the potential influence of educational initiatives in addressing AA. This study
Externí odkaz:
https://doaj.org/article/ac4bc2f34e874d3e87df71b1b797a43f
Autor:
Michael Pfeiffer, John Boehmer, John Gorcsan, Shunsuke Eguchi, Yoshiyuki Orihara, Michal Laufer Perl, Neal Eigler, William T. Abraham, Julio Nuñez Villota, Elizabeth Lee, Antoni Bayés‐Genís, Gil Moravsky, Saibal Kar, Michael R. Zile, Richard Holcomb, Stefan D. Anker, Gregg W. Stone, Josep Rodés‐Cabau, JoAnn Lindenfeld, Jeroen J. Bax
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 2499-2509 (2024)
Abstract Aims Interatrial shunts are under evaluation as a treatment for heart failure (HF); however, their in vivo flow performance has not been quantitatively studied. We aimed to investigate the fluid dynamics properties of the 0.51 cm orifice dia
Externí odkaz:
https://doaj.org/article/6422d42a82654ee9a74441c13147c265
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Introduction Disparities in HIV and other sexually transmitted infections (STIs) persist among cisgender sexually minoritized men in the United States, driven in part by sexual behavior stigma, which is a barrier to clinic-based HIV/STI test
Externí odkaz:
https://doaj.org/article/bca2f31c87bc48948299eb829395b157
Autor:
Femke C.C. Klouwer, Stefan D. Roosendaal, Carla E. M. Hollak, Mirjam Langeveld, Bwee Tien Poll-The, Arlette J. van Sorge, Nicole I. Wolf, Marjo S. van der Knaap, Marc Engelen
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Alpha-methylacyl-CoA racemase (AMACR) deficiency is a rare peroxisomal enzyme deficiency caused by biallelic variants in the AMACR gene. This deficiency leads to the accumulation of toxic bile acid intermediates (R)-trihydroxychol
Externí odkaz:
https://doaj.org/article/06bcf3f754ad448a8d1311bfc4c466de
Autor:
David Fitchett, Bernard Zinman, Silvio E. Inzucchi, Christoph Wanner, Stefan D. Anker, Stuart Pocock, Michaela Mattheus, Ola Vedin, Søren S. Lund
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-7 (2024)
Abstract Background The effect of empagliflozin, a sodium-glucose-co-transporter-2 inhibitor, on risk for myocardial infarction has not been fully characterized. Methods This study comprised prespecified and post-hoc analyses of the EMPA-REG OUTCOME
Externí odkaz:
https://doaj.org/article/e033bb1ddc7949bca3ef1b0df0c3d965
Autor:
Michael S. Yule, Joshua Thompson, Khachonphat Leesahatsawat, Mariana S. Sousa, Stefan D. Anker, Jann Arends, Trude R. Balstad, Leo R. Brown, Asta Bye, Olav Dajani, Marie Fallon, Marianne J. Hjermstad, Gunnhild Jakobsen, James McDonald, Josh McGovern, Eric J. Roeland, Judith Sayers, Richard J.E. Skipworth, Inger O. Ottestad, Iain Philips, Melanie R. Simpson, Tora S. Solheim, Ola Magne Vagnildhaug, Donald McMillan, Barry J.A. Laird, Ross D. Dolan, the Cancer Cachexia Endpoints Working Group
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 853-867 (2024)
Abstract Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement of biomarkers featu
Externí odkaz:
https://doaj.org/article/b91388b921c54b20be4595865bc85c5f
Autor:
Ambarish Pandey, Kershaw V. Patel, Matthew W. Segar, Colby Ayers, Jennifer Linge, Olof D. Leinhard, Stefan D. Anker, Javed Butler, Subodh Verma, Parag H. Joshi, Ian J. Neeland
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1072-1083 (2024)
Abstract Background Excess muscle fat is observed in obesity and associated with greater burden of cardiovascular risk factors and higher risk of mortality. Liraglutide reduces total body weight and visceral fat but its effect on muscle fat and adver
Externí odkaz:
https://doaj.org/article/92db8ec390084a5689cbd26e4b0cae3c
Autor:
Hsi‐Yu Lai, Shih‐Tsung Huang, Stefan D. Anker, Stephan vonHaehling, Masahiro Akishita, Hidenori Arai, Liang‐Kung Chen, Fei‐Yuan Hsiao
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 660-670 (2024)
Abstract Background Frailty often coexists with heart failure (HF), which significantly aggravates the clinical outcomes of older adults. However, studies investigating the interplay between frailty and HF in older adults are scarce. We aimed to asse
Externí odkaz:
https://doaj.org/article/7e08e146e8cd4649b78f08681a95e35f
Autor:
Maria Simonenko, Dominique Hansen, Josef Niebauer, Maurizio Volterrani, Stamatis Adamopoulos, Cristiano Amarelli, Marco Ambrosetti, Stefan D. Anker, Antonio Bayes-Genis, Tuvia Ben Gal, T. Scott Bowen, Francesco Cacciatore, Giuseppe Caminiti, Elena Cavarretta, Ovidiu Chioncel, Andrew J. S. Coats, Alain Cohen-Solal, Flavio D’Ascenzi, Carmen de Pablo Zarzosa, Andreas B. Gevaert, Finn Gustafsson, Hareld Kemps, Loreena Hill, Tiny Jaarsma, Ewa Jankowska, Emer Joyce, Nicolle Krankel, Mitja Lainscak, Lars H. Lund, Brenda Moura, Kari Nytrøen, Elena Osto, Massimo Piepoli, Luciano Potena, Amina Rakisheva, Giuseppe Rosano, Gianluigi Savarese, Petar M. Seferovic, David R. Thompson, Thomas Thum, Emeline M. Van Craenenbroeck
Publikováno v:
Transplant International, Vol 37 (2024)
Little is known either about either physical activity patterns, or other lifestyle-related prevention measures in heart transplantation (HTx) recipients. The history of HTx started more than 50 years ago but there are still no guidelines or position
Externí odkaz:
https://doaj.org/article/4ccdc9317262421e9229c4fb891db94d