Zobrazeno 1 - 10
of 1 014
pro vyhledávání: '"Stefan Bräse"'
Autor:
AbdElAziz A. Nayl, Esmail M. El-Fakharany, Ahmed I. Abd-Elhamid, Wael A. A. Arafa, Ahmed H. Alanazi, Ismail M. Ahmed, Mohamed A. Abdelgawad, Ashraf A. Aly, Stefan Bräse
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract It is imperative to explore new biocompatible drugs with low toxicity for use in medicinal fields such as fighting tumors. Bovine lactoperoxidase (BLPO) stems from the most important enzymes in the bovine whey that provide a proper pattern f
Externí odkaz:
https://doaj.org/article/c8d4042fcf0c462babf30fe7659d66e3
Autor:
Madeleine G. Moule, Aaron B. Benjamin, Melanie L. Burger, Claudine Herlan, Maxim Lebedev, Jennifer S. Lin, Kent J. Koster, Neha Wavare, Leslie G. Adams, Stefan Bräse, Ricardo Munoz-Medina, Carolyn L. Cannon, Annelise E. Barron, Jeffrey D. Cirillo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The rise of drug resistance has become a global crisis, with >1 million deaths due to resistant bacterial infections each year. Pseudomonas aeruginosa, in particular, remains a serious problem with limited solutions due to complex resistance
Externí odkaz:
https://doaj.org/article/ab40fd863f304eb4a471e70484e74673
Autor:
Lamya H. Al-Wahaibi, Ali M. Elshamsy, Taha F. S. Ali, Bahaa G. M. Youssif, Stefan Bräse, Mohamed Abdel-Aziz, Nawal A. El-Koussi
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34358-34369 (2024)
Externí odkaz:
https://doaj.org/article/0622e5e444ce4009a24da2b2b6498639
Autor:
Lamya H. Al-Wahaibi, Mostafa H. Abdel-Rahman, Khaled El-Adl, Bahaa G. M. Youssif, Stefan Bräse, Salah A. Abdel-Aziz
Publikováno v:
ACS Omega, Vol 9, Iss 31, Pp 33494-33509 (2024)
Externí odkaz:
https://doaj.org/article/27f72febc8164dbd8bb26422d74a6dbe
Autor:
Simone Gräßle, Laura Holzhauer, Nicolai Wippert, Olaf Fuhr, Martin Nieger, Nicole Jung, Stefan Bräse
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1396-1404 (2024)
A synthesis route to access triazole–pyrazole hybrids via triazenylpyrazoles was developed. Contrary to existing methods, this route allows the facile N-functionalization of the pyrazole before the attachment of the triazole unit via a copper-catal
Externí odkaz:
https://doaj.org/article/b334d831695d45069d60fb967475988d
Autor:
Yaser A. Mostafa, Jalil Abdeljalil Assoud, Ahmed Y. Desoky, Samy Mohamady, Nesma M. Mohamed, Ola I. A. Salem, Zainab M. Almarhoon, Stefan Bräse, Bahaa G. M. Youssif
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
IntroductionWe developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2.MethodsThe antiproliferative efficacy of the novel targets was assessed against a panel of 60 NCI cancer cell lines
Externí odkaz:
https://doaj.org/article/6cd27a190de540de84af81cc18e46b04
Autor:
Zhen Zhang, Rongrong Xia, Ke Wang, Youjun Wu, Panpan Zang, Xuemin Gan, Zhangcheng Liao, Bin Wei, Peng Wu, Stefan Bräse, Zixing Wang
Publikováno v:
Aggregate, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Thermally activated delayed fluorescence (TADF) molecules are regarded as promising materials for realizing high‐performance organic light‐emitting diodes (OLEDs). The connecting groups between donor (D) and acceptor (A) units in D–A t
Externí odkaz:
https://doaj.org/article/a02f970a5d184041b30c7dfc3f716106
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Materials exhibiting thermally activated delayed fluorescence (TADF) based on transition metal complexes are currently gathering significant attention due to their technological potential. Their application extends beyond optoelectronics, in
Externí odkaz:
https://doaj.org/article/ea43174b1fc3452586a0e404670c767d
Autor:
Lamya H. Al-Wahaibi, Hesham A. Abou-Zied, Mostafa H. Abdelrahman, Martha M. Morcoss, Laurent Trembleau, Bahaa G. M. Youssif, Stefan Bräse
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The present study details the design, synthesis, and bio-evaluation of indoles 3–16 as dual inhibitors of aromatase and inducible nitric oxide synthase (iNOS)with antiproliferative activity. The study evaluates the antiproliferative efficacy of 3
Externí odkaz:
https://doaj.org/article/39a0c8a8c6484f1a92f6ac096afce3c5
Autor:
Mohamed A. Mahmoud, Anber F. Mohammed, Ola I. A. Salem, Tahani Mazyad Almutairi, Stefan Bräse, Bahaa G. M. Youssif
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractA novel series of 1,2,3-triazole/1,2,4-oxadiazole hybrids (7a–o) was developed as dual inhibitors of EGFR/VEGFR-2. Compounds 7a–o were evaluated as antiproliferative agents with Erlotinib as the reference drug. Results demonstrated that m
Externí odkaz:
https://doaj.org/article/5d8c004b623b4255ac1faff7a6b1a4ac