Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stefan Brüchert"'
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-7 (2020)
Communications Biology
Communications Biology
Polyacrylamide gel electrophoresis (PAGE) and immunoblotting (Western blotting) are the most common methods in life science. In conjunction with these methods, the polyhistidine-tag has proven to be a superb fusion tag for protein purification as wel
Autor:
Eric R. Geertsma, Erich Stefan, Dovile Januliene, Christoph Thomas, Ahmad Reza Mehdipour, Susanne Hofmann, Stefan Brüchert, Arne Moeller, Gerhard Hummer, Benedikt T Kuhn, Robert Tampé
Publikováno v:
Nature
Cryo-electron microscopy (cryo-EM) has the capacity to capture molecular machines in action1-3. ATP-binding cassette (ABC) exporters are highly dynamic membrane proteins that extrude a wide range of substances from the cytosol4-6 and thereby contribu
Autor:
Rupert Abele, Ahmad Reza Mehdipour, Vincent Olieric, Thomas M. Tomasiak, Klaas M. Pos, Anne Nöll, Stefan Brüchert, Robert M. Stroud, Christoph Thomas, Kay Diederichs, Meitian Wang, Gerhard Hummer, Robert Tampé, Benesh Joseph, Tina Zollmann, Valentina Herbring, Katja Barth
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(4)
ABC transporters form one of the largest protein superfamilies in all domains of life, catalyzing the movement of diverse substrates across membranes. In this key position, ABC transporters can mediate multidrug resistance in cancer therapy and their