Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stefan Blaho"'
Autor:
Birgitta Karlsson Svalstedt, Anders Thelin, Annika Wellner, Johanna Vinblad, Margareta Herslöf, David Gustafsson, Yantao Chen, Cristian Bodin, Ola Fjellström, Stefan Blaho, Jenny Sandmark, Carina Johansson, Birgitta Rosengren, Sofia Martinsson, Tomas Fex, Jonas Boström, Andreas Moberg, Tomas Akerud, Emma Evertsson, Bingze Xu, Ryan Hicks, Magnus Althage, Emelie Jarkvist, Wolfgang Knecht, Per-Olof Eriksson, Marianne Ridderström, Ann-Margret Östlund-Lindqvist, Anna Tigerström, Anders Dahlén, Anne Legnehed, Thomas Antonsson, Alan Sabirsh, Inge Kalies, Fredrik Kartberg
Publikováno v:
J Biol Chem
Increased plasma concentrations of lipoprotein(a) (Lp(a)) are associated with an increased risk for cardiovascular disease. Lp(a) is composed of apolipoprotein(a) (apo(a)) covalently bound to apolipoprotein B of low-density lipoprotein (LDL). Many of
Autor:
Stefan Blaho, Mathias Liljeblad, Mikko Hölttä, Fredrik Höök, Stefan Geschwindner, Namik Akkilic
Publikováno v:
ACS Sensors. 4:3166-3174
Biomarkers serve as indicators of disease progression or therapeutic response of an medical intervention, and means for enabling a reliable and sensitive biomarker detection are therefore vital in clinical settings. Most biosensor assays require high
Autor:
Gangadhara Gangadhara, Nils Pemberton, Kostas Karabelas, Rebecca Rae, Mickael Mogemark, Christian Tyrchan, Tineke Papavoine, Göran Dahl, Perry Matthew, Helena Lindmark, Stefan Blaho, Linda Öster, Jenny Gunnarsson, Thomas Bohnacker, Matthias P. Wymann, Jens Petersen, Roger L. Williams
Publikováno v:
Nature chemical biology. 15(4)
We have discovered a class of PI3Kγ inhibitors exhibiting over 1,000-fold selectivity over PI3Kα and PI3Kβ. On the basis of X-ray crystallography, hydrogen-deuterium exchange-mass spectrometry and surface plasmon resonance experiments we propose t
Autor:
Emre M. Isin, David Blomberg Saitton, Eric Wellner, Rutger H. A. Folmer, Pernilla Ståhlberg, Kay Brickmann, Volker Schnecke, Öjvind Davidsson, Christoffer Bengtsson, Lars-Olof Larsson, Stefan Hallén, Pernilla Sörme, Hong Wan, Kenth Hallberg, Linda Öster, Ragnar Hovland, Lars Löfgren, Alleyn T. Plowright, Bengt Kull, Tobias Noeske, Stefan Blaho, Petra Johannesson, Tomas Drmota, Kristina Nilsson, Johan Broddefalk, Nick Oakes
Publikováno v:
Bioorganicmedicinal chemistry. 19(10)
Inhibition of acetyl-CoA carboxylases has the potential for modulating long chain fatty acid biosynthesis and mitochondrial fatty acid oxidation. Hybridization of weak inhibitors of ACC2 provided a novel, moderately potent but lipophilic series. Opti