Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Stefan Balabanov"'
Autor:
Mattheus H. E. Wildschut, Julien Mena, Cyril Dördelmann, Marc van Oostrum, Benjamin D. Hale, Jens Settelmeier, Yasmin Festl, Veronika Lysenko, Patrick M. Schürch, Alexander Ring, Yannik Severin, Michael S. Bader, Patrick G. A. Pedrioli, Sandra Goetze, Audrey van Drogen, Stefan Balabanov, Radek C. Skoda, Massimo Lopes, Bernd Wollscheid, Alexandre P. A. Theocharides, Berend Snijder
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Myelofibrosis is a hematopoietic stem cell disorder belonging to the myeloproliferative neoplasms. Myelofibrosis patients frequently carry driver mutations in either JAK2 or Calreticulin (CALR) and have limited therapeutic options. Here, we
Externí odkaz:
https://doaj.org/article/be42116607d44feb831a5d12924ccd1b
A multicenter real-world evidence study in the Swiss treatment landscape of chronic myeloid leukemia
Autor:
Nathan Cantoni, Roberto Sommavilla, Patrick Seitz, Elisabeth Kulenkampff, Stefan Kahn, Jean-François Lambert, Adrian Schmidt, Reinhard Zenhaeusern, Stefan Balabanov
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The real-world experience of Swiss chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs) is largely unknown, in particular with regard to achievement of response per European Leukemia Net (ELN) cri
Externí odkaz:
https://doaj.org/article/b6ab3f1aa7334dc6819ecce935003b14
Autor:
Ekaterina S. Menchinskaya, Sergey A. Dyshlovoy, Simone Venz, Christine Jacobsen, Jessica Hauschild, Tina Rohlfing, Aleksandra S. Silchenko, Sergey A. Avilov, Stefan Balabanov, Carsten Bokemeyer, Dmitry L. Aminin, Gunhild von Amsberg, Friedemann Honecker
Publikováno v:
Marine Drugs, Vol 22, Iss 1, p 20 (2023)
Despite recent advances in the treatment of metastatic castration-resistant prostate cancer (CRPC), treatment is inevitably hampered by the development of drug resistance. Thus, new drugs are urgently needed. We investigated the efficacy, toxicity, a
Externí odkaz:
https://doaj.org/article/ef96dfc1e6784c86a537b7ae846cbe5e
Autor:
Erik Hameister, Sebastian M. Stolz, Yvonne Fuhrer, Friedrich Thienemann, Dominik J. Schaer, Johannes Nemeth, Reto A. Schuepbach, Jeroen Goede, Sophie Reinhart, Adrian Schmidt, Abdullah Kahraman, Mathias Schmid, Holger Moch, Martin Zoche, Markus G. Manz, Stefan Balabanov, Steffen Boettcher
Publikováno v:
HemaSphere, Vol 4, Iss 4, p e453 (2020)
Externí odkaz:
https://doaj.org/article/e79aaaae979c4a5588fc3e7f2152370d
Autor:
Henning Sievert, Nora Pällmann, Katharine K. Miller, Irm Hermans-Borgmeyer, Simone Venz, Ataman Sendoel, Michael Preukschas, Michaela Schweizer, Steffen Boettcher, P. Christoph Janiesch, Thomas Streichert, Reinhard Walther, Michael O. Hengartner, Markus G. Manz, Tim H. Brümmendorf, Carsten Bokemeyer, Melanie Braig, Joachim Hauber, Kent E. Duncan, Stefan Balabanov
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 8, Pp 963-976 (2014)
The central importance of translational control by post-translational modification has spurred major interest in regulatory pathways that control translation. One such pathway uniquely adds hypusine to eukaryotic initiation factor 5A (eIF5A), and the
Externí odkaz:
https://doaj.org/article/1c3ec82d54394b81a23dc5254fab1567
Autor:
Daniel Benten, Gunhild Keller, Alexander Quaas, Jorg Schrader, Artur Gontarewicz, Stefan Balabanov, Melanie Braig, Henning Wege, Jurgen Moll, Ansgar W. Lohse, Tim H. Brummendorf
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 9, Pp 934-944 (2009)
Patients with advanced stages of hepatocellular carcinoma (HCC) face a poor prognosis. Although encouraging clinical results have been obtained with multikinase inhibitor sorafenib, the development of improved therapeutic strategies for HCC remains a
Externí odkaz:
https://doaj.org/article/f44d5427273e43cfa4258d1f4c805c2b
Autor:
Benjamin Werner, Fabian Beier, Sebastian Hummel, Stefan Balabanov, Lisa Lassay, Thorsten Orlikowsky, David Dingli, Tim H Brümmendorf, Arne Traulsen
Publikováno v:
eLife, Vol 4 (2015)
We investigate the in vivo patterns of stem cell divisions in the human hematopoietic system throughout life. In particular, we analyze the shape of telomere length distributions underlying stem cell behavior within individuals. Our mathematical mode
Externí odkaz:
https://doaj.org/article/ee6ccd70808b4901b2cb8518dd1b1514
Autor:
Jasmin Wellbrock, Sara Sheikhzadeh, Leticia Oliveira-Ferrer, Hauke Stamm, Mathias Hillebrand, Britta Keyser, Marianne Klokow, Gabi Vohwinkel, Veronika Bonk, Benjamin Otto, Thomas Streichert, Stefan Balabanov, Christian Hagel, Meike Rybczynski, Frank Bentzien, Carsten Bokemeyer, Yskert von Kodolitsch, Walter Fiedler
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104742 (2014)
The Loeys-Dietz syndrome (LDS) is an inherited connective tissue disorder caused by mutations in the transforming growth factor β (TGF-β) receptors TGFBR1 or TGFBR2. Most patients with LDS develop severe aortic aneurysms resulting in early need of
Externí odkaz:
https://doaj.org/article/3088706ae18c4df79590a1535a20ef75
Autor:
Stefan Balabanov, Thomas Wilhelm, Simone Venz, Gunhild Keller, Christian Scharf, Heike Pospisil, Melanie Braig, Christine Barett, Carsten Bokemeyer, Reinhard Walther, Tim H Brümmendorf, Andreas Schuppert
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53668 (2013)
In drug discovery, the characterisation of the precise modes of action (MoA) and of unwanted off-target effects of novel molecularly targeted compounds is of highest relevance. Recent approaches for identification of MoA have employed various techniq
Externí odkaz:
https://doaj.org/article/f5ef203a54d44cec9bc3e7b68936836e
Autor:
Michael Preukschas, Christian Hagel, Alexander Schulte, Kristoffer Weber, Katrin Lamszus, Henning Sievert, Nora Pällmann, Carsten Bokemeyer, Joachim Hauber, Melanie Braig, Stefan Balabanov
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43468 (2012)
Glioblastomas are highly aggressive brain tumors of adults with poor clinical outcome. Despite a broad range of new and more specific treatment strategies, therapy of glioblastomas remains challenging and tumors relapse in all cases. Recent work demo
Externí odkaz:
https://doaj.org/article/be8aa09ce7fd49a9bb62600e7a6decc7