Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Stefan B. Hosch"'
Autor:
Christian Vay, Stefan B Hosch, Nikolas H Stoecklein, Christoph A Klein, Daniel Vallböhmer, Björn-Christian Link, Emre F Yekebas, Jakob R Izbicki, Wolfram T Knoefel, Peter Scheunemann
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e109026 (2014)
The integrins are a family of heterodimeric transmembrane signaling receptors that mediate the adhesive properties of epithelial cells affecting cell growth and differentiation. In many epithelial malignancies, altered integrin expression is associat
Externí odkaz:
https://doaj.org/article/9b508e66608046f6a9f0be6f6859ff58
Autor:
C. Vay, Annika Siegmund, Wolfram T. Knoefel, Pablo E. Verde, Jakob R. Izbicki, Paulus G. Schurr, Nikolas H. Stoecklein, Claudia H. Hartmann, Andreas Erbersdobler, Axel Ullrich, Peter Scheunemann, Uta Reichelt, Franziska Stern, Roger Grau, Stefan B. Hosch, Christoph Klein, Martin Bezler
Publikováno v:
Cancer Cell. 13:441-453
SummaryThe increasing use of primary tumors as surrogate markers for prognosis and therapeutic decisions neglects evolutionary aspects of cancer progression. To address this problem, we studied the precursor cells of metastases directly for the ident
Autor:
J. Schulte am Esch, Stefan B. Hosch, Peter Scheunemann, Claus F. Eisenberger, Sylvia Metz, Nikolas H. Stoecklein, M. Bidde, Wolfram T. Knoefel, Alexander Rehders, Matthias Peiper
Publikováno v:
HPB. 9:135-139
Background: Occurrence of tumor relapse is frequent in patients with carcinoma of the papilla of Vater despite the absence of residual tumor detectable at primary surgery. Therefore it has to be assumed that current tumor staging procedures fail to i
Publikováno v:
Chemotherapy. 53:356-359
This is a report about a patient who had a complete remission of a metastatic pancreatic adenocarcinoma after a modified G-FLIP therapy administered in an outpatient setting. The patient underwent surgery and the complete remission could be proven hi
Autor:
Stefan B. Hosch, Nikolas H. Stoecklein, Peter Scheunemann, Claus F. Eisenberger, J. Schulte am Esch, Matthias Peiper, S. Jazra, Wolfram T. Knoefel
Publikováno v:
European Journal of Surgical Oncology (EJSO). 32:954-960
Background and aims Organ-confined oesophageal cancer in an early stage can be cured in many patients, whereas more extensive lesions have a poor prognosis. We sought to develop a non-invasive test for cancer detection and evaluation of the prognosis
Autor:
Jan Schulte am Esch nd, Andreas Krieg, Stefan B. Hosch, Csaba Mahotka, Helmut E. Gabbert, Wolfram T. Knoefel, Uwe Ramp
Publikováno v:
Biochemical and Biophysical Research Communications. 349:115-121
Transcriptional modification by alternative splicing is known to be involved in the regulation of programmed cell death. Recently, alternative splice variants of the TNF-related apoptosis inducing ligand (TRAIL/APO2L) and of the death receptor TRAIL-
Autor:
Niko Feifel, F.A.C.S. Wolfram Trudo Knoefel M.D., Guenter Fuerst, Matthias Peiper, Nikolas H. Stoecklein, Jan Schulte am Esch, Christoph Piechaczek, Ludger Wilhelm Poll, Ali Ghodsizad, Elmar R. Burchardt, M Stockschläder, M. Klein, Volker R. Stoldt, Claus F. Eisenberger, Stefan B. Hosch, Roy Y. Tustas, Dieter Häussinger
Publikováno v:
STEM CELLS. 23:463-470
The liver has a large capacity for regeneration after resection. However, below a critical level of future liver remnant volume (FLRV), partial hepatectomy is accompanied by a significant increase of postoperative liver failure. There is accumulating
Autor:
Peter Scheunemann, Jakob R. Izbicki, Andreas M. Luebke, Pablo E. Verde, Matthias Peiper, Stefan B. Hosch, Franziska Stern, Claus F. Eisenberger, Christoph Klein, Nikolas H. Stoecklein, Wolfram T. Knoefel, Andreas Erbersdobler, Winfried Schraut
Publikováno v:
Journal of Clinical Oncology. 22:4737-4745
Purpose To determine the frequency and the potential clinical use of HER2 (17q21) gene amplification and chromosome 17 aneuploidy in pancreatic ductal adenocarcinoma (PDAC). Materials and Methods Serial tissue sections of 50 resected PDACs were analy
Autor:
Jakob R. Izbicki, Stefan B. Hosch, Wolfram T. Knoefel, David Zurakowski, Matthias Peiper, Antje Heinecke, Claus F. Eisenberger, T Sato
Publikováno v:
Oncology Research and Treatment. 26:268-271
The expression of HER2/neu has been identified as a prognostic factor in several malignant diseases. However, only sparse data exist correlating HER2/neu expression in soft tissue sarcoma with subsequent tumor progression or recurrence. The purpose o
Publikováno v:
Journal of Hepato-Biliary-Pancreatic Surgery. 9:583-591
Despite advances in early diagnosis and surgical treatment, the prognosis for patients with primary malignant tumors of the hepatobiliary tract and pancreas has not changed markedly over the last decades. Early metastatic relapse after complete resec