Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Stefan B Eichmüller"'
Autor:
Sebastian Uhrig, Carsten Müller-Tidow, Stefan Fröhling, Hartmut Goldschmidt, Michael Platten, Michael Hundemer, Niklas Kehl, Michael Kilian, Julius Michel, Tim R Wagner, Alexander Brobeil, Lilli-Sophie Sester, Sven Blobner, Simon Steiger, Niels Weinhold, Karsten Rippe, Stefan B Eichmüller, Lukas Bunse, Marc-Steffen Raab, Mirco J Friedrich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Multiple myeloma (MM) is a hematological malignancy originating from malignant and clonally expanding plasma cells. MM can be molecularly stratified, and its clonal evolution deciphered based on the Ig heavy and light chains of the respective maligna
Externí odkaz:
https://doaj.org/article/f0969d97b65c4cd4b532d155f2790750
Autor:
Franziska Hörhold, David Eisel, Marcus Oswald, Amol Kolte, Daniela Röll, Wolfram Osen, Stefan B Eichmüller, Rainer König
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1007657 (2020)
Upon exposure to different stimuli, resting macrophages undergo classical or alternative polarization into distinct phenotypes that can cause fatal dysfunction in a large range of diseases, such as systemic infection leading to sepsis or the generati
Externí odkaz:
https://doaj.org/article/4bba50c0a81b451b884c8ed48721d89e
Autor:
Krishna Das, David Eisel, Clarissa Lenkl, Ashish Goyal, Sven Diederichs, Elke Dickes, Wolfram Osen, Stefan B Eichmüller
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209719 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0174077.].
Externí odkaz:
https://doaj.org/article/09f0e8116f624d85890febe147a546cb
Autor:
Krishna Das, David Eisel, Clarissa Lenkl, Ashish Goyal, Sven Diederichs, Elke Dickes, Wolfram Osen, Stefan B Eichmüller
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174077 (2017)
In this study, the CRISPR/Cas9 technology was used to establish murine tumor cell lines, devoid of MHC I or MHC II surface expression, respectively. The melanoma cell line B16F10 and the murine breast cancer cell line EO-771, the latter stably expres
Externí odkaz:
https://doaj.org/article/14f4d3e8def64cdab705fa9a6d4dfbb2
Autor:
Wolfram Osen, Sabine Soltek, Mingxia Song, Barbara Leuchs, Julia Steitz, Thomas Tüting, Stefan B Eichmüller, Xuan-Duc Nguyen, Dirk Schadendorf, Annette Paschen
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14137 (2010)
BACKGROUND: As tumor antigen-specific CD4+ T cells can mediate strong therapeutic anti-tumor responses in melanoma patients we set out to establish a comprehensive screening strategy for the identification of tumor-specific CD4+ T cell epitopes suita
Externí odkaz:
https://doaj.org/article/416996c27aa840adbd2416ddfea8c376
Autor:
Marten Meyer, Christina Parpoulas, Titouan Barthélémy, Jonas P. Becker, Pornpimol Charoentong, Yanhong Lyu, Selina Börsig, Nadja Bulbuc, Claudia Tessmer, Lisa Weinacht, David Ibberson, Patrick Schmidt, Rüdiger Pipkorn, Stefan B. Eichmüller, Peter Steinberger, Katharina Lindner, Isabel Poschke, Michael Platten, Stefan Fröhling, Angelika B. Riemer, Jessica C. Hassel, Maria Paula Roberti, Dirk Jäger, Inka Zörnig, Frank Momburg
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and specificity. To improve the discovery of T cell receptors (TCR) targeting neoantigens of indiv
Externí odkaz:
https://doaj.org/article/2562f0907ae7489481331f6d349419cb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape. For example, upregulated expression of ecto-5′-nucleotidase (NT5E), also
Externí odkaz:
https://doaj.org/article/99f8db80e9794297bf78de8cef6ad88d
Autor:
Antonino A. Pane, Theresa Kordaß, Agnes Hotz‐Wagenblatt, Elke Dickes, Annette Kopp‐Schneider, Rainer Will, Barbara Seliger, Wolfram Osen, Stefan B. Eichmüller
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Background The regulatory functions of microRNAs (miRNAs) in anti‐tumour immunity have been mainly described in immune effector cells. Since little is known about miRNA effects on the susceptibility of target cells during T cell—target c
Externí odkaz:
https://doaj.org/article/38e9049add3e449e936d98a7f8389382
Publikováno v:
Molecular and Cellular Biochemistry. 478:305-315
The transcription factor SOX9 represents an important mediator of breast cancer progression. miRNAs are small non-coding RNAs inhibiting translation of target genes upon interaction with the 3′-UTR region of respective mRNA molecules. Deregulated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b12414c03c7e5227840ad89fdb3bd7
https://doi.org/10.1007/s11010-022-04507-z
https://doi.org/10.1007/s11010-022-04507-z
Autor:
Stefan B. Eichmüller, Pavel P. Philippov, Evgeni Yu Zernii, Robert W. Owen, Dirk Schadendorf, Alexandr V. Bazhin
Proteins involved in the visual signaling cascade show light-dependent expression levels in photoreceptor cells. Recently, these proteins have been described to be expressed in neuroectodermal tumors and to function as cancer-retina antigens. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d785792d96e2b78c85143e16ad98d73
https://doi.org/10.1158/1541-7786.c.6543078.v1
https://doi.org/10.1158/1541-7786.c.6543078.v1
