Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Stefan B, Eichmüller"'
Autor:
Marten Meyer, Christina Parpoulas, Titouan Barthélémy, Jonas P. Becker, Pornpimol Charoentong, Yanhong Lyu, Selina Börsig, Nadja Bulbuc, Claudia Tessmer, Lisa Weinacht, David Ibberson, Patrick Schmidt, Rüdiger Pipkorn, Stefan B. Eichmüller, Peter Steinberger, Katharina Lindner, Isabel Poschke, Michael Platten, Stefan Fröhling, Angelika B. Riemer, Jessica C. Hassel, Maria Paula Roberti, Dirk Jäger, Inka Zörnig, Frank Momburg
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and specificity. To improve the discovery of T cell receptors (TCR) targeting neoantigens of indiv
Externí odkaz:
https://doaj.org/article/2562f0907ae7489481331f6d349419cb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape. For example, upregulated expression of ecto-5′-nucleotidase (NT5E), also
Externí odkaz:
https://doaj.org/article/99f8db80e9794297bf78de8cef6ad88d
Autor:
Antonino A. Pane, Theresa Kordaß, Agnes Hotz‐Wagenblatt, Elke Dickes, Annette Kopp‐Schneider, Rainer Will, Barbara Seliger, Wolfram Osen, Stefan B. Eichmüller
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Background The regulatory functions of microRNAs (miRNAs) in anti‐tumour immunity have been mainly described in immune effector cells. Since little is known about miRNA effects on the susceptibility of target cells during T cell—target c
Externí odkaz:
https://doaj.org/article/38e9049add3e449e936d98a7f8389382
Autor:
Sebastian Uhrig, Carsten Müller-Tidow, Stefan Fröhling, Hartmut Goldschmidt, Michael Platten, Michael Hundemer, Niklas Kehl, Michael Kilian, Julius Michel, Tim R Wagner, Alexander Brobeil, Lilli-Sophie Sester, Sven Blobner, Simon Steiger, Niels Weinhold, Karsten Rippe, Stefan B Eichmüller, Lukas Bunse, Marc-Steffen Raab, Mirco J Friedrich
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Multiple myeloma (MM) is a hematological malignancy originating from malignant and clonally expanding plasma cells. MM can be molecularly stratified, and its clonal evolution deciphered based on the Ig heavy and light chains of the respective maligna
Externí odkaz:
https://doaj.org/article/f0969d97b65c4cd4b532d155f2790750
Autor:
Laura Hartmann, Philipp Schröter, Wolfram Osen, Daniel Baumann, Rienk Offringa, Mahmoud Moustafa, Rainer Will, Jürgen Debus, Stephan Brons, Stefan Rieken, Stefan B. Eichmüller
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract While for photon radiation hypofractionation has been reported to induce enhanced immunomodulatory effects, little is known about the immunomodulatory potential of carbon ion radiotherapy (CIRT). We thus compared the radio-immunogenic effect
Externí odkaz:
https://doaj.org/article/922b225c3b544655b294c9222875593d
Autor:
Krishna Das, David Eisel, Mathias Vormehr, Karin Müller-Decker, Adriane Hommertgen, Dirk Jäger, Inka Zörnig, Markus Feuerer, Annette Kopp-Schneider, Wolfram Osen, Stefan B. Eichmüller
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background NY-BR-1 has been described as a breast cancer associated differentiation antigen with intrinsic immunogenicity giving rise to endogenous T and B cell responses. The current study presents the first murine tumor model allowing func
Externí odkaz:
https://doaj.org/article/d268bf3988f443859f4c202b5d7dad25
Autor:
Franziska Hörhold, David Eisel, Marcus Oswald, Amol Kolte, Daniela Röll, Wolfram Osen, Stefan B Eichmüller, Rainer König
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1007657 (2020)
Upon exposure to different stimuli, resting macrophages undergo classical or alternative polarization into distinct phenotypes that can cause fatal dysfunction in a large range of diseases, such as systemic infection leading to sepsis or the generati
Externí odkaz:
https://doaj.org/article/4bba50c0a81b451b884c8ed48721d89e
Publikováno v:
Molecular and Cellular Biochemistry. 478:305-315
The transcription factor SOX9 represents an important mediator of breast cancer progression. miRNAs are small non-coding RNAs inhibiting translation of target genes upon interaction with the 3′-UTR region of respective mRNA molecules. Deregulated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b12414c03c7e5227840ad89fdb3bd7
https://doi.org/10.1007/s11010-022-04507-z
https://doi.org/10.1007/s11010-022-04507-z
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The immunosuppressive tumor microenvironment (TME) established by tumor cells, stromal cells and inhibitory immune cells counteracts the function of tumor reactive T cells. Tumor associated macrophages (TAMs) showing functional plasticity contribute
Externí odkaz:
https://doaj.org/article/959c4eb5504e48d79699131e747e81b9
Autor:
Stefan B. Eichmüller, Pavel P. Philippov, Evgeni Yu Zernii, Robert W. Owen, Dirk Schadendorf, Alexandr V. Bazhin
Proteins involved in the visual signaling cascade show light-dependent expression levels in photoreceptor cells. Recently, these proteins have been described to be expressed in neuroectodermal tumors and to function as cancer-retina antigens. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d785792d96e2b78c85143e16ad98d73
https://doi.org/10.1158/1541-7786.c.6543078.v1
https://doi.org/10.1158/1541-7786.c.6543078.v1
