Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stefan Audehm"'
Autor:
Melanie Boxberg, Katja Steiger, Wilko Weichert, Roland Rad, Kai Yu, Sebastian Lange, Thomas Engleitner, Huan Lan, Eva Bräunlein, Gaia Lupoli, Franziska Füchsl, Esam T Abualrous, Niklas de Andrade Krätzig, Dario Gosmann, Lukas Wietbrock, Stefan Audehm, Manuel Effenberger, Yinshui Chang, Cigdem Atay, Florian Bassermann, Dirk H Busch, Christian Freund, Iris Antes, Angela M Krackhardt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/1b3e7f5e07ff4e049642ff6e60339d61
Autor:
Stefan Audehm, Manuel Glaser, Matteo Pecoraro, Eva Bräunlein, Sabine Mall, Richard Klar, Manuel Effenberger, Julian Albers, Henrique de Oliveira Bianchi, Janet Peper, Nahid Yusufi, Dirk H. Busch, Stefan Stevanović, Matthias Mann, Iris Antes, Angela M. Krackhardt
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Adoptive transfer of T cells transgenic for tumor-reactive T-cell receptors (TCR) is an attractive immunotherapeutic approach. However, clinical translation is so far limited due to challenges in the identification of suitable target antigens as well
Externí odkaz:
https://doaj.org/article/22a2a126e49249719ac2dc109a786b0d
Autor:
Michal Bassani-Sternberg, Eva Bräunlein, Richard Klar, Thomas Engleitner, Pavel Sinitcyn, Stefan Audehm, Melanie Straub, Julia Weber, Julia Slotta-Huspenina, Katja Specht, Marc E. Martignoni, Angelika Werner, Rüdiger Hein, Dirk H. Busch, Christian Peschel, Roland Rad, Jürgen Cox, Matthias Mann, Angela M. Krackhardt
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Neoantigens determine anti-cancer immunoreactivity and are important functional targets for immunotherapy. Here, the authors use deep mass spectrometry to characterize neoepitopes from human melanoma tissue and show the presence of tumour-reactive T
Externí odkaz:
https://doaj.org/article/9d43ba6c8b234b1ab6f92d398fb3a892
Autor:
Angela M. Krackhardt, Calogero D'Alessandria, Markus Schwaiger, Mona Mustafa, Sibylle Ziegler, Christian Peschel, Michaela Aichler, Iina Laitinen, Stefan Audehm, Melanie Straub, Katja Steiger, Henrique Bianchi, Richard Klar, Ricarda Wagner, Nahid Yusufi, Sabine Mall
Supplementary Material and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8042744a49618a204d456ce7dab518de
https://doi.org/10.1158/0008-5472.22408166.v1
https://doi.org/10.1158/0008-5472.22408166.v1
Autor:
Angela M. Krackhardt, Calogero D'Alessandria, Markus Schwaiger, Mona Mustafa, Sibylle Ziegler, Christian Peschel, Michaela Aichler, Iina Laitinen, Stefan Audehm, Melanie Straub, Katja Steiger, Henrique Bianchi, Richard Klar, Ricarda Wagner, Nahid Yusufi, Sabine Mall
Sensitive in vivo imaging technologies applicable to the clinical setting are still lacking for adoptive T-cell–based immunotherapies, an important gap to fill if mechanisms of tumor rejection or escape are to be understood. Here, we propose a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c778eaca6690d1bae23be696e2ba313
https://doi.org/10.1158/0008-5472.c.6507479.v1
https://doi.org/10.1158/0008-5472.c.6507479.v1
Autor:
Angela M. Krackhardt, Calogero D'Alessandria, Markus Schwaiger, Mona Mustafa, Sibylle Ziegler, Christian Peschel, Michaela Aichler, Iina Laitinen, Stefan Audehm, Melanie Straub, Katja Steiger, Henrique Bianchi, Richard Klar, Ricarda Wagner, Nahid Yusufi, Sabine Mall
Investigation of different imaging time points to track TCR-transduced TCM after injection of 89Zr-aTCRmu-F(ab')2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8c96c8d472334d7be42f228abdb0f1
https://doi.org/10.1158/0008-5472.22408181
https://doi.org/10.1158/0008-5472.22408181
Autor:
Franziska Füchsl, Christian Freund, Lukas Wietbrock, Stefan Audehm, Thomas Engleitner, Kai Yu, Cigdem Atay, Angela M. Krackhardt, Wilko Weichert, Yinshui Chang, Katja Steiger, Esam T. Abualrous, Gaia Lupoli, Iris Antes, Eva Bräunlein, Florian Bassermann, Roland Rad, Dario Gosmann, Melanie Boxberg, Dirk H. Busch, Sebastian Lange, Manuel Effenberger, Niklas de Andrade Krätzig, Huan Lan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
BackgroundNeoantigens derived from somatic mutations correlate with therapeutic responses mediated by treatment with immune checkpoint inhibitors. Neoantigens are therefore highly attractive targets for the development of therapeutic approaches in pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50092b4d1235fcbc56d767e07868dce5
https://jitc.bmj.com/content/9/9/e002754.full
https://jitc.bmj.com/content/9/9/e002754.full
Autor:
Huan Lan, Kang Yu, de Andrade Krätzig N, Eva Bräunlein, Thomas Engleitner, Katja Steiger, Wilko Weichert, Wietbrock L, Melanie Boxberg, Angela M. Krackhardt, Dario Gosmann, Stefan Audehm, Iris Antes, Atay C, Roland Rad, Füchsl F, Christian Freund, Dirk H. Busch, Florian Bassermann, G. Lupoli, Manuel Effenberger, Esam T. Abualrous, Chang Y, Sebastian Lange
Neoantigens derived from somatic mutations have been demonstrated to correlate with therapeutic responses mediated by treatment with immune checkpoint inhibitors. Neoantigens are therefore highly attractive targets for the development of personalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c37f7e516684c36cecaee7c5072e614
https://doi.org/10.1101/2021.02.02.428777
https://doi.org/10.1101/2021.02.02.428777
Autor:
Stephan G. Nekolla, Sybille Reder, Markus Schwaiger, Calogero D'Alessandria, Henrique de Oliveira Bianchi, Mona Mustafa, Angela M. Krackhardt, Stefan Audehm, Sabine Mall, Nahid Yusufi, Katja Steiger, Richard Klar, Christian Peschel
Publikováno v:
Theranostics
A number of different technologies have been developed to monitor in vivo the distribution of gene-modified T cells used in immunotherapy. Nevertheless, in-depth characterization of novel approaches with respect to sensitivity and clinical applicabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d945d270992c01b0d72387a45bc7de
https://doi.org/10.7150/thno.17994
https://doi.org/10.7150/thno.17994
Autor:
Jürgen Ruland, Florian Bassermann, Tim Ammon, Martina Anton, Anja Stelzl, Katja Steiger, Anja Wolf, Silvia Thoene, Ramona Secci, Christof Winter, Angela M. Krackhardt, Stefan Audehm, Dario Gosmann, Christian Kupatt, Julian J Albers
Publikováno v:
Life Science Alliance
Targeted integration of a tumor-reactive T-cell receptor into the TRAC locus using CRISPR-Cas9 and AAV6 redirects primary human T cells against tumor cells in vitro and in vivo.
Adoptive transfer of TCR transgenic T cells holds great promise for
Adoptive transfer of TCR transgenic T cells holds great promise for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381b9a9d2c5f1867d0ad69f7316836f8
https://pubmed.ncbi.nlm.nih.gov/30877233
https://pubmed.ncbi.nlm.nih.gov/30877233