Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Stefan Alig"'
Autor:
Ryan C. Lynch, Stefan Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Andrei Shustov, Brian Till, Vikram M. Raghunathan, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jackie Vandermeer, Ashley Gaston, Heather Rasmussen, Avanti Gulhane, Delphine L. Chen, Paul Martin, Edmond Marzbani, Jenna Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Publikováno v:
HemaSphere, Vol 6, Pp 26-27 (2022)
Externí odkaz:
https://doaj.org/article/1dca62dfced740de83e0d17bd541a259
Autor:
Deepak Bararia, Johannes A. Hildebrand, Sebastian Stolz, Sarah Haebe, Stefan Alig, Christopher P. Trevisani, Francisco Osorio-Barrios, Michael D. Bartoschek, Michael Mentz, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, Katharina Rautter, Jay Gunawardana, Muhammed B. Sabdia, Monika Szczepanowski, Julia Richter, Wolfram Klapper, Abner Louissaint, Jr., Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, Michael von Bergwelt-Baildon, Christian Steidl, Robert Kridel, Joshua W.D. Tobin, Maher K. Gandhi, David M. Weinstock, Marc Schmidt-Supprian, Menyhárt B. Sárosi, Martina Rudelius, Verena Passerini, Josef Mautner, Oliver Weigert
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Tumor cells orchestrate their microenvironment. Here, we provide biochemical, structural, functional, and clinical evidence that Cathepsin S (CTSS) alterations induce a tumor-promoting immune microenvironment in follicular lymphoma (FL). We
Externí odkaz:
https://doaj.org/article/0a5e722ca6e94029b574353537c7475f
Autor:
Stefan Alig, Vindi Jurinovic, Alessandro Pastore, Deepak Bararia, Sarah Häbe, Johannes C. Hellmuth, Robert Kridel, Randy Gascoyne, Christian Schmidt, Anna-Katharina Zöllner, Christian Buske, Martin Dreyling, Michael Unterhalt, Wolfgang Hiddemann, Eva Hoster, Oliver Weigert
Publikováno v:
Haematologica, Vol 103, Iss 8 (2018)
Externí odkaz:
https://doaj.org/article/478a70586fc84a1594a3b12415030b14
Autor:
Elisabeth Koch, Joachim Pircher, Thomas Czermak, Erik Gaitzsch, Stefan Alig, Hanna Mannell, Markus Niemeyer, Florian Krötz, Markus Wörnle
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Introduction. Inflammation and endothelium-derived superoxides are important pathomechanisms in atherothrombotic diseases. We could previously show that the tyrosine phosphatase SHP-1 acts as a negative regulator in endothelial superoxide production.
Externí odkaz:
https://doaj.org/article/b34079ea41cd48baab01b33ff6091694
Autor:
Joseph G. Schroers-Martin, Stefan Alig, Andrea Garofalo, Benoit Tessoulin, Takeshi Sugio, Ash A. Alizadeh
Publikováno v:
Annual Review of Pathology: Mechanisms of Disease. 18:149-180
Molecular monitoring of tumor-derived alterations has an established role in the surveillance of leukemias, and emerging nucleic acid sequencing technologies are likely to similarly transform the clinical management of lymphomas. Lymphomas are well s
Autor:
Michael R. Green, Ari M. Melnick, Robert G. Roeder, David A. Scheinberg, Ahmet Dogan, Cassian Yee, Anas Younes, José Baselga, Giorgio Inghirami, Oliver Weigert, Sattva S. Neelapu, Loretta Nastoupil, Anja Mottok, Sreejoyee Ghosh, Elisa de Stanchina, Matthew Durant, Stefan Alig, Eneda Toska, Man Chun John Ma, Chi-Shuen Chu, Hsia-Yuan Ying, Shailbala Singh, Haopeng Yang, Neeraj Jain, Aaron Y. Chang, Lorena Fontan, Matt Teater, Saber Tadros, Patrizia Mondello
CREBBP mutations are highly recurrent in B-cell lymphomas and either inactivate its histone acetyltransferase (HAT) domain or truncate the protein. Herein, we show that these two classes of mutations yield different degrees of disruption of the epige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb7bba8de5d9c0f34e402cf5507947e
https://doi.org/10.1158/2159-8290.c.6547819.v1
https://doi.org/10.1158/2159-8290.c.6547819.v1
Autor:
Michael R. Green, Ari M. Melnick, Robert G. Roeder, David A. Scheinberg, Ahmet Dogan, Cassian Yee, Anas Younes, José Baselga, Giorgio Inghirami, Oliver Weigert, Sattva S. Neelapu, Loretta Nastoupil, Anja Mottok, Sreejoyee Ghosh, Elisa de Stanchina, Matthew Durant, Stefan Alig, Eneda Toska, Man Chun John Ma, Chi-Shuen Chu, Hsia-Yuan Ying, Shailbala Singh, Haopeng Yang, Neeraj Jain, Aaron Y. Chang, Lorena Fontan, Matt Teater, Saber Tadros, Patrizia Mondello
Figures S1 - S16 Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849a13b68a5b6bdd264f3e7fa3284959
https://doi.org/10.1158/2159-8290.22535296
https://doi.org/10.1158/2159-8290.22535296
Autor:
Michael R. Green, Ari M. Melnick, Robert G. Roeder, David A. Scheinberg, Ahmet Dogan, Cassian Yee, Anas Younes, José Baselga, Giorgio Inghirami, Oliver Weigert, Sattva S. Neelapu, Loretta Nastoupil, Anja Mottok, Sreejoyee Ghosh, Elisa de Stanchina, Matthew Durant, Stefan Alig, Eneda Toska, Man Chun John Ma, Chi-Shuen Chu, Hsia-Yuan Ying, Shailbala Singh, Haopeng Yang, Neeraj Jain, Aaron Y. Chang, Lorena Fontan, Matt Teater, Saber Tadros, Patrizia Mondello
Tables S1 - S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb9144a42622bae6c58224155a904bc
https://doi.org/10.1158/2159-8290.22535293.v1
https://doi.org/10.1158/2159-8290.22535293.v1
Autor:
Ryan C Lynch, Chaitra S Ujjani, Christina Poh, Edus H Warren, Stephen D Smith, Mazyar Shadman, Brian G. Till, Vikram Raghunathan, Stefan Alig, Ash A Alizadeh, Avanti Gulhane, Delphine Chen, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jacquelin Vandermeer, Ashley Gaston, Heather Rasmussen, Paul Martin, Edmond Marzbani, Jenna M Voutsinas, Ajay K Gopal
Publikováno v:
Blood.
Concurrent administration pembrolizumab with chemotherapy in untreated classical Hodgkin lymphoma (CHL) has not previously been studied. To investigate this combination, we conducted a single arm study of concurrent pembrolizumab with AVD (APVD) for
Autor:
Mari Olsen, David M. Kurtz, Mark Roschewski, Brian Sworder, Davide Rossi, Florian Scherer, Ulrich Dührsen, Andre Schultz, Andrea Garofalo, Joseph G Schroers-Martin, Jason R. Westin, Wyndham H. Wilson, Charles Macaulay, Emily G. Hamilton, Alexander F.M. Craig, Gianluca Gaidano, Binbin Chen, Jacob J. Chabon, Andreas Hüttmann, René-Olivier Casasnovas, Ash A. Alizadeh, Maximilian Diehn, Michael C. Jin, Chih Long Liu, Lyron Co Ting Keh, Stefan Alig, Joanne Soo, Mohammad Shahrokh Esfahani, Everett J. Moding
Publikováno v:
Nature biotechnology
Circulating tumor DNA (ctDNA) is an emerging biomarker for many cancers, but the limited sensitivity of current detection methods reduces its utility for diagnosing minimal residual disease. Here we describe phased variant enrichment and detection se