Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Stefan A. Wudy"'
Autor:
Eva Kathrin Lamadé, Bruno Pedraz-Petrozzi, Ole Lindner, Pascal Meininger, Antonia Pisters, Maria Gilles, Stephanie H. Witt, Marcella Rietschel, Helene Dukal, Fabian Schunk, Michaela Coenen, Stefan A. Wudy, Rainer Hellweg, Michael Deuschle
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100658- (2024)
Introduction: At the maternal-fetal interface in pregnancy, stress during pregnancy can lead to an increased vulnerability to later psychopathology of the fetus. Potential mediators of this association have scarcely been studied and may include early
Externí odkaz:
https://doaj.org/article/e3652d240a3d4159aa8447d9624c2b1a
Autor:
Leah T. Braun, Andrea Osswald, Stephanie Zopp, German Rubinstein, Frederick Vogel, Anna Riester, Jürgen Honegger, Graeme Eisenhofer, Georgiana Constantinescu, Timo Deutschbein, Marcus Quinkler, Ulf Elbelt, Heike Künzel, Hanna F. Nowotny, Nicole Reisch, Michaela F. Hartmann, Felix Beuschlein, Jörn Pons-Kühnemann, Martin Reincke, Stefan A. Wudy
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104907- (2024)
Summary: Background: Diagnosing Cushing’s syndrome (CS) is highly complex. As the diagnostic potential of urinary steroid metabolome analysis by gas chromatography-mass spectrometry (GC-MS) in combination with systems biology has not yet been fully
Externí odkaz:
https://doaj.org/article/150c72c68c42466f90f11b1e75850b6a
Autor:
Yiran Zheng, Luisa Sophie Rajcsanyi, Triinu Peters, Astrid Dempfle, Stefan A. Wudy, Johannes Hebebrand, Anke Hinney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Recent studies reported an impact of the melanocortin 3 receptor (MC3R) on the regulation of body weight, linear growth and puberty timing. Previously, allele p.44Ile of a frequent non-synonymous variant (NSV) p.Val44Ile was reported to be a
Externí odkaz:
https://doaj.org/article/9ceac8f0bab34ca0bdc41e5842e0e6fa
Autor:
Shamini Ramkumar Thirumalasetty, Tina Schubert, Ronald Naumann, Ilka Reichardt, Marie-Luise Rohm, Dana Landgraf, Florian Gembardt, Mirko Peitzsch, Michaela F. Hartmann, Mihail Sarov, Stefan A. Wudy, Nicole Reisch, Angela Huebner, Katrin Koehler
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5062 (2024)
Congenital Adrenal Hyperplasia (CAH) is an autosomal recessive disorder impairing cortisol synthesis due to reduced enzymatic activity. This leads to persistent adrenocortical overstimulation and the accumulation of precursors before the blocked enzy
Externí odkaz:
https://doaj.org/article/d53e98ed726046359880ca4c318162f7
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Objective To evaluate the impact of anti-tumor necrosis factor-alpha (TNFα: etanercept [Etanercept ®]) therapy on adrenal activity in juvenile idiopathic arthritis (JIA) . Method Eleven JIA patients aged 12 ± 6.2 years with a disease dura
Externí odkaz:
https://doaj.org/article/ab16052cbfc74e84a748f6121263206b
Autor:
Matthias Heckmann, Anna S. Runkel, Donna E. Sunny, Michaela F. Hartmann, Till Ittermann, Stefan A. Wudy
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 235 (2024)
Adrenal function is essential for survival and well-being of preterm babies. In addition to glucocorticoids, it has been hypothesized that C19-steroids (DHEA-metabolites) from the fetal zone of the adrenal gland may play a role as endogenous neuropro
Externí odkaz:
https://doaj.org/article/efd163043d444745bc26712d833a0991
Autor:
Seyedeh-Masomeh Derakhshandeh-Rishehri, Luciana Peixoto Franco, Yifan Hua, Christian Herder, Hermann Kalhoff, Lynda A. Frassetto, Stefan A. Wudy, Thomas Remer
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1408 (2024)
High dietary phosphorus intake (P-In) and high acid loads may adversely affect kidney function. In animal models, excessive phosphorus intake causes renal injury, which, in humans, is also inducible by chronic metabolic acidosis. We thus examined whe
Externí odkaz:
https://doaj.org/article/04f016464d624af2bdc513cb6930f60a
Autor:
Michaela Kuhlen, Marina Kunstreich, Lienhard Lessel, Stefan A. Wudy, Paul-Martin Holterhus, Christian Vokuhl, Eva Juettner, Christoph Roecken, Guido Seitz, Christoph Slavetinsky, Jörg Fuchs, Denis M. Schewe, Rainer Claus, Pascal D. Johann, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
EJC Paediatric Oncology, Vol 1, Iss , Pp 100015- (2023)
Background: Paediatric adrenocortical carcinomas (ACC) are highly aggressive malignancies with a dismal prognosis in advanced and metastatic diseases. Little is known about outcome of patients with refractory and relapsed (r/r) disease. Procedure: Na
Externí odkaz:
https://doaj.org/article/87befb459f374e449313ef4fba15ab29
Autor:
Michaela Kuhlen, Pascal Mier, Marina Kunstreich, Lienhard Lessel, Christoph Slavetinsky, Jörg Fuchs, Guido Seitz, Paul-Martin Holterhus, Stefan A. Wudy, Christian Vokuhl, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Cancers, Vol 15, Iss 17, p 4296 (2023)
Background: Locally advanced tumors account for approximately 50% of children and adolescents with adrenocortical carcinoma (ACC), and of these, up to 50% relapse. We explored the five-item microscopic score and the pS-GRAS score for guiding manageme
Externí odkaz:
https://doaj.org/article/bc4fb899e0ca4f959db57ea9c052d085
Autor:
Michaela Kuhlen, Christina Pamporaki, Marina Kunstreich, Stefan A. Wudy, Michaela F. Hartmann, Mirko Peitzsch, Christian Vokuhl, Guido Seitz, Michael C. Kreissl, Thorsten Simon, Barbara Hero, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In children and adolescents, neuroblastoma (NBL), pheochromocytoma (PCC), and adrenocortical tumors (ACT) can arise from the adrenal gland. It may be difficult to distinguish between these three entities including associated extra-adrenal tumors (par
Externí odkaz:
https://doaj.org/article/ac8972243d7a4ddfbb8232006990456e