Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stefan A Paschen"'
Autor:
Jan G Christian, Julia Heymann, Stefan A Paschen, Juliane Vier, Linda Schauenburg, Jan Rupp, Thomas F Meyer, Georg Häcker, Dagmar Heuer
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002283 (2011)
Chlamydiae are obligate intracellular bacteria that propagate in a cytosolic vacuole. Recent work has shown that growth of Chlamydia induces the fragmentation of the Golgi apparatus (GA) into ministacks, which facilitates the acquisition of host lipi
Externí odkaz:
https://doaj.org/article/64a7729b870c4dbe93a680cbcad2cace
Autor:
Pedro Eitz Ferrer, Stephanie Potthoff, Susanne Kirschnek, Georg Gasteiger, Wolfgang Kastenmüller, Holger Ludwig, Stefan A Paschen, Andreas Villunger, Gerd Sutter, Ingo Drexler, Georg Häcker
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002083 (2011)
Viral infection is a stimulus for apoptosis, and in order to sustain viral replication many viruses are known to carry genes encoding apoptosis inhibitors. F1L, encoded by the orthopoxvirus modified vaccinia virus Ankara (MVA) has a Bcl-2-like struct
Externí odkaz:
https://doaj.org/article/b2a18fb60b3b46f3bf1d8cf5cc6b39f8
Autor:
Philip Kahl, Uta Drebber, Alexander C. Adam, Olaf Adam, Hans-Peter Fischer, Stefan A. Paschen, Reinhard Büttner, Viola Faudou
Publikováno v:
The Journal of Pathology. 228:333-340
We investigated circumscribed cell proliferations in healthy livers in comparison to non-cirrhotic livers bearing hepatocellular carcinoma. Using histochemical staining for cytochrome c oxidase, the fourth complex of the respiratory chain, we visuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28100569a7e43d4f768d84ffcdba8015
https://doi.org/10.1002/path.4060
https://doi.org/10.1002/path.4060
Autor:
Juliane Vier, David M. Ojcius, Georg Häcker, Stefan A. Paschen, Jan G. Christian, Axel Walch, Franziska Schmidt
Publikováno v:
The Journal of Cell Biology
Chlamydiae replicate in a vacuole within epithelial cells and commonly induce cell damage and a deleterious inflammatory response of unknown molecular pathogenesis. The chlamydial protease-like activity factor (CPAF) translocates from the vacuole to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914713e7a95359c3cd089407060baca1
https://doi.org/10.1083/jcb.200804023
https://doi.org/10.1083/jcb.200804023
Publikováno v:
Microbes and Infection. 10:97-101
Infection with Chlamydia protects mammalian host cells against apoptosis. Hypotheses have been proposed to explain this molecularly, including the up-regulation of host anti-apoptotic proteins such as cellular Inhibitor of Apoptosis Protein (IAP) 2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085aa6cb865332b459d07e773aed1c62
https://doi.org/10.1016/j.micinf.2007.10.005
https://doi.org/10.1016/j.micinf.2007.10.005
Autor:
Georg Häcker, Stefan A. Paschen
Publikováno v:
Expert Opinion on Therapeutic Targets. 11:515-526
Every cell in the human body has most of the components of the apoptotic apparatus and is thus principally equipped to die by apoptosis. Situations of increased or decreased apoptosis contribute to many forms of human disease, making this pathway an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b474d218dc5451b9d72175e5a2f98c63
https://doi.org/10.1517/14728222.11.4.515
https://doi.org/10.1517/14728222.11.4.515
Autor:
Susanne Kirschnek, Arnim Weber, Klaus Heger, Georg Häcker, Heike Bauerschmitt, Tobias Frankenberg, Stefan A. Paschen, Barbara M. Seiffert, Hermann Wagner, Florian Wilfling
Publikováno v:
The Journal of Cell Biology
Release of apoptogenic proteins such as cytochrome c from mitochondria is regulated by pro- and anti-apoptotic Bcl-2 family proteins, with pro-apoptotic BH3-only proteins activating Bax and Bak. Current models assume that apoptosis induction occurs v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f1e5aece07ad7de31b16e61b0d6fce
http://europepmc.org/articles/PMC2064208
http://europepmc.org/articles/PMC2064208
Publikováno v:
Trends in Biochemical Sciences. 30:575-582
beta-Barrel membrane proteins have several important functions in outer membranes of Gram-negative bacteria and in the organelles of endosymbiotic origin, mitochondria and chloroplasts. The biogenesis of beta-barrel membrane proteins was, until recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcafc65b3b9629f748d2a08e25be06ab
https://doi.org/10.1016/j.tibs.2005.08.009
https://doi.org/10.1016/j.tibs.2005.08.009
Autor:
Shukry J. Habib, Dejana Mokranjac, Walter Neupert, Doron Rapaport, Stefan A. Paschen, Maciej Lech, Thomas Waizenegger, Kai Hell
Publikováno v:
EMBO reports. 5:704-709
Insertion of beta-barrel proteins into the outer membrane of mitochondria is mediated by the TOB complex. Known constituents of this complex are Tob55 and Mas37. We identified a novel component, Tob38. It is essential for viability of yeast and the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017152f7a6b45efcfd51be0a3b3dbb03
https://doi.org/10.1038/sj.embor.7400183
https://doi.org/10.1038/sj.embor.7400183
Autor:
Kai Hell, Marek Cyrklaff, Thomas Waizenegger, Tincuta Stan, Marc Preuss, Walter Neupert, Doron Rapaport, Stefan A. Paschen
Publikováno v:
Nature. 426:862-866
The outer membranes of mitochondria and chloroplasts are distinguished by the presence of β-barrel membrane proteins1,2. The outer membrane of Gram-negative bacteria also harbours β-barrel proteins3. In mitochondria these proteins fulfil a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d67bd199af03fe995a02f0297645b0
https://doi.org/10.1038/nature02208
https://doi.org/10.1038/nature02208