Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Stefan A, Wudy"'
Autor:
Luciana Peixoto Franco, Seyedeh-Masomeh Derakhshandeh-Rishehri, Ute Nöthlings, Michaela F. Hartmann, Christian Herder, Hermann Kalhoff, Stefan A. Wudy, Thomas Remer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The bone-derived hormone FGF23, primarily secreted by osteocytes, is a major player in the regulation of phosphate homeostasis. It becomes upregulated by increased circulating phosphate concentration, e.g. due to elevations in phosphorus int
Externí odkaz:
https://doaj.org/article/cc9906ed691b4c99a04f5d78aa05cf02
Autor:
Eva Kathrin Lamadé, Bruno Pedraz-Petrozzi, Ole Lindner, Pascal Meininger, Antonia Pisters, Maria Gilles, Stephanie H. Witt, Marcella Rietschel, Helene Dukal, Fabian Schunk, Michaela Coenen, Stefan A. Wudy, Rainer Hellweg, Michael Deuschle
Publikováno v:
Neurobiology of Stress, Vol 31, Iss , Pp 100658- (2024)
Introduction: At the maternal-fetal interface in pregnancy, stress during pregnancy can lead to an increased vulnerability to later psychopathology of the fetus. Potential mediators of this association have scarcely been studied and may include early
Externí odkaz:
https://doaj.org/article/e3652d240a3d4159aa8447d9624c2b1a
Autor:
Yiran Zheng, Luisa Sophie Rajcsanyi, Triinu Peters, Astrid Dempfle, Stefan A. Wudy, Johannes Hebebrand, Anke Hinney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Recent studies reported an impact of the melanocortin 3 receptor (MC3R) on the regulation of body weight, linear growth and puberty timing. Previously, allele p.44Ile of a frequent non-synonymous variant (NSV) p.Val44Ile was reported to be a
Externí odkaz:
https://doaj.org/article/9ceac8f0bab34ca0bdc41e5842e0e6fa
Autor:
Leah T. Braun, Andrea Osswald, Stephanie Zopp, German Rubinstein, Frederick Vogel, Anna Riester, Jürgen Honegger, Graeme Eisenhofer, Georgiana Constantinescu, Timo Deutschbein, Marcus Quinkler, Ulf Elbelt, Heike Künzel, Hanna F. Nowotny, Nicole Reisch, Michaela F. Hartmann, Felix Beuschlein, Jörn Pons-Kühnemann, Martin Reincke, Stefan A. Wudy
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104907- (2024)
Summary: Background: Diagnosing Cushing’s syndrome (CS) is highly complex. As the diagnostic potential of urinary steroid metabolome analysis by gas chromatography-mass spectrometry (GC-MS) in combination with systems biology has not yet been fully
Externí odkaz:
https://doaj.org/article/150c72c68c42466f90f11b1e75850b6a
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Objective To evaluate the impact of anti-tumor necrosis factor-alpha (TNFα: etanercept [Etanercept ®]) therapy on adrenal activity in juvenile idiopathic arthritis (JIA) . Method Eleven JIA patients aged 12 ± 6.2 years with a disease dura
Externí odkaz:
https://doaj.org/article/ab16052cbfc74e84a748f6121263206b
Autor:
Matthias Heckmann, Anna S. Runkel, Donna E. Sunny, Michaela F. Hartmann, Till Ittermann, Stefan A. Wudy
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 235 (2024)
Adrenal function is essential for survival and well-being of preterm babies. In addition to glucocorticoids, it has been hypothesized that C19-steroids (DHEA-metabolites) from the fetal zone of the adrenal gland may play a role as endogenous neuropro
Externí odkaz:
https://doaj.org/article/efd163043d444745bc26712d833a0991
Autor:
Martijn J J Finken, Aleid J G Wirix, Ines A von Rosenstiel-Jadoul, Bibian van der Voorn, Mai J M Chinapaw, Michaela F Hartmann, Joana E Kist-van Holthe, Stefan A Wudy, Joost Rotteveel
Publikováno v:
Endocrine Connections, Vol 11, Iss 7, Pp 1-7 (2022)
Objective: Childhood obesity is associated with alterations in hypothalamus–pituitary– adrenal axis activity. We tested the hypothesis that multiple alterations in the metabolism of glucocorticoids are required for the development of hypertension
Externí odkaz:
https://doaj.org/article/557f87071bfa4e7da5988930dc534c2b
Autor:
Michaela Kuhlen, Marina Kunstreich, Lienhard Lessel, Stefan A. Wudy, Paul-Martin Holterhus, Christian Vokuhl, Eva Juettner, Christoph Roecken, Guido Seitz, Christoph Slavetinsky, Jörg Fuchs, Denis M. Schewe, Rainer Claus, Pascal D. Johann, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
EJC Paediatric Oncology, Vol 1, Iss , Pp 100015- (2023)
Background: Paediatric adrenocortical carcinomas (ACC) are highly aggressive malignancies with a dismal prognosis in advanced and metastatic diseases. Little is known about outcome of patients with refractory and relapsed (r/r) disease. Procedure: Na
Externí odkaz:
https://doaj.org/article/87befb459f374e449313ef4fba15ab29
Autor:
Michaela Kuhlen, Christina Pamporaki, Marina Kunstreich, Stefan A. Wudy, Michaela F. Hartmann, Mirko Peitzsch, Christian Vokuhl, Guido Seitz, Michael C. Kreissl, Thorsten Simon, Barbara Hero, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In children and adolescents, neuroblastoma (NBL), pheochromocytoma (PCC), and adrenocortical tumors (ACT) can arise from the adrenal gland. It may be difficult to distinguish between these three entities including associated extra-adrenal tumors (par
Externí odkaz:
https://doaj.org/article/ac8972243d7a4ddfbb8232006990456e
Autor:
Britt J van Keulen, Michelle Romijn, Bibian van der Voorn, Marita de Waard, Michaela F Hartmann, Johannes B van Goudoever, Stefan A Wudy, Joost Rotteveel, Martijn J J Finken
Publikováno v:
Endocrine Connections, Vol 10, Iss 2, Pp 214-219 (2021)
Objective: Sex-specific differences in hypothalamic–pituitary–adrenal axis activity might explain why male preterm infants are at higher risk of neonatal mortality and morbidity than their female counterparts. We examined whether male and female
Externí odkaz:
https://doaj.org/article/6523c9200944419c92c3a5d4160b0519