Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Stefan Ryckaert"'
Autor:
Erik Vanderbeke, Nico Callewaert, Ann Depicker, Vikram Virdi, Stefan Ryckaert, Jorge Palaci, Eric Cox, Bram Laukens
Publikováno v:
NATURE BIOTECHNOLOGY
Nature biotechnology
Nature biotechnology
Oral antibodies that interfere with gastrointestinal targets and can be manufactured at scale are needed. Here we show that a single-gene-encoded monomeric immunoglobulin A (IgA)-like antibody, composed of camelid variable single domain antibodies (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c91a25b0fa889cb9a6110d6d3d4016e
https://biblio.ugent.be/publication/8611521/file/8611522
https://biblio.ugent.be/publication/8611521/file/8611522
Autor:
Roland Contreras, Nico Callewaert, Sylviane Dewaele, Stefan Ryckaert, Pieter P. Jacobs, Isabelle Dewerte
Publikováno v:
Glycobiology. 18:137-144
The establishment of a robust technology platform for the expression cloning of carbohydrate-binding proteins remains a key challenge in glycomics. Here we explore the utility of using yeast surface display (YSD) technology in the interaction-based l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89121a02e37865c433b5840a2e53404f
https://doi.org/10.1093/glycob/cwm131
https://doi.org/10.1093/glycob/cwm131
Publikováno v:
Journal of biotechnology. 145(2)
Yeast surface display is an efficient tool for isolating and engineering antibody fragments, both scFv and Fab. We describe the use of protein display on Pichia pastoris for the rapid selection of camelid antibodies composed only of heavy chains (nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4182ee727cd6c549666dafa5d772aae
https://pubmed.ncbi.nlm.nih.gov/19861136
https://pubmed.ncbi.nlm.nih.gov/19861136
Autor:
Roland Contreras, Steven Geysens, Pieter P. Jacobs, Stefan Ryckaert, Kristof De Vusser, Nico Callewaert
Publikováno v:
Biotechnology letters. 30(12)
Expression of proteins on the surface of yeasts has a wide range of applications in biotechnology, such as directed evolution of proteins for increased affinity and thermal stability, screening of antibody libraries, epitope mapping, and use as whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defe579428868e48742bfe46a849f0e7
https://pubmed.ncbi.nlm.nih.gov/18679585
https://pubmed.ncbi.nlm.nih.gov/18679585
Publikováno v:
Journal of biotechnology. 119(4)
Absence of sialylation on recombinant glycoproteins compromises their efficacy as therapeutic agents, as it results in rapid clearance from the human bloodstream. To circumvent this, several strategies are followed, including the implementation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673dffcf6485134e9427d5952bd24e9a
https://pubmed.ncbi.nlm.nih.gov/15982773
https://pubmed.ncbi.nlm.nih.gov/15982773
Autor:
Paul Ameloot, Stefan Ryckaert, Pieter P. Jacobs, Nico Callewaert, Mouna Guerfal, Riet Derycke, Kathleen Van Craenenbroeck
Publikováno v:
MICROBIAL CELL FACTORIES
Microbial Cell Factories, Vol 9, Iss 1, p 49 (2010)
Microbial Cell Factories
Microbial Cell Factories, Vol 9, Iss 1, p 49 (2010)
Microbial Cell Factories
Background The unfolded protein response (UPR) in eukaryotes upregulates factors that restore ER homeostasis upon protein folding stress and in yeast is activated by a non-conventional splicing of the HAC1 mRNA. The spliced HAC1 mRNA encodes an activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4462cca09964d908e375f3d2c1ce68
Fishing for lectins from diverse sequence libraries by yeast surface display - An exploratory study.
Autor:
Stefan Ryckaert, Nico Callewaert, Pieter P. Jacobs, Sylviane Dewaele, Isabelle Dewerte, Roland Contreras
Publikováno v:
Glycobiology; Feb2008, Vol. 18 Issue 2, p137-137, 1p