Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Stefan, Zielen"'
Autor:
Ruth P. Duecker, Oguzhan Alemdar, Andreas Wimmers, Lucia Gronau, Andreas G. Chiocchetti, Eva M. Valesky, Helena Donath, Jordis Trischler, Katharina Blumchen, Stefan Zielen, Ralf Schubert
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1356 (2024)
A high proportion of house dust mite (HDM)-allergic asthmatics suffer from both an early asthmatic reaction (EAR) and a late asthmatic reaction (LAR) which follows it. In these patients, allergic inflammation is more relevant. MiRNAs have been shown
Externí odkaz:
https://doaj.org/article/3432f482515b43b0a1f422ddf6a26a32
Autor:
Pia Schuchmann, Gerhard Scheuch, Rolf Naumann, Marius Keute, Thomas Lücke, Stefan Zielen, Folke Brinkmann
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundAvailable data on aerosol emissions among children and adolescents during spontaneous breathing are limited. Our aim was to gain insight into the role of children in the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Externí odkaz:
https://doaj.org/article/fb9f1aa58c264ff3b1f12c78cdf431d9
Autor:
Marina Reichlmeir, Júlia Canet-Pons, Gabriele Koepf, Wasifa Nurieva, Ruth Pia Duecker, Claudia Doering, Kathryn Abell, Jana Key, Matthew P. Stokes, Stefan Zielen, Ralf Schubert, Zoltán Ivics, Georg Auburger
Publikováno v:
Cells, Vol 12, Iss 19, p 2399 (2023)
The autosomal recessive disorder Ataxia-Telangiectasia is caused by a dysfunction of the stress response protein, ATM. In the nucleus of proliferating cells, ATM senses DNA double-strand breaks and coordinates their repair. This role explains T-cell
Externí odkaz:
https://doaj.org/article/db755476b80843dbad5c7f067ecc1ecd
Autor:
Silvija P. Jerkic, Laura Bächle, Ruth Pia Duecker, Lucia Gronau, Andreas G. Chiocchetti, Stefan Zielen, Ralf Schubert
Publikováno v:
Mediators of Inflammation, Vol 2023 (2023)
Introduction. Bronchiolitis obliterans (BO) is a chronic lung disease, which occurs after an insult to the lower airways, in particular after airway infections or after stem cell transplantation, and which results in persistent inflammation. N–3 an
Externí odkaz:
https://doaj.org/article/0b4097ff71264eceb82b916ba42eabb1
Autor:
Joern Pascal Laubach, Michael Ludwig, Tabea Horn, Olaf Eickmeier, Christina Smaczny, Ralf Schubert, Stefan Zielen, Christof Majoor, Malik Aydin, Alexander Schnell, Sabina Schmitt-Grohé
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 7, p 138 (2023)
Background: High TGFβ1-producing variants cause severe clinical disease in F508del homozygous patients. Lately, we showed that a single nucleotide polymorphism (SNP), rs41266431, in the GJA4 gene modifies the disease severity of cystic fibrosis (CF)
Externí odkaz:
https://doaj.org/article/16d181019809414886fb939000eab2b6
Autor:
Stanley J. Szefler, Graham Roberts, Adalberto S. Rubin, Stefan Zielen, Piotr Kuna, Oral Alpan, Judith Anzures‐Cabrera, Qiang Chen, Cécile T. J. Holweg, Janusz Kaminski, Wendy S. Putnam, John G. Matthews, Nikhil Kamath
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Lebrikizumab is a monoclonal antibody that modulates activity of interleukin‐13. The Phase 3 ACOUSTICS study assessed lebrikizumab efficacy and safety in adolescents with uncontrolled asthma despite standard‐of‐care treatmen
Externí odkaz:
https://doaj.org/article/95330c9a733f48b0baef545bd3c87bf6
Autor:
Desiree Gutmann, Helena Donath, Laura Herrlich, Timon Lehmkühler, Anton Landeis, Emily R. Ume, Martin Hutter, Ann-Kathrin Goßmann, Frederik Weis, Maximilian Weiß, Holger F. Rabenau, Stefan Zielen
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundChildren and adolescents seem to be less affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease in terms of severity, especially until the increasing spread of the omicron variant in December 2021. Anatomical s
Externí odkaz:
https://doaj.org/article/d7db70e085d4496788a79775cdd1cc3c
Autor:
Susanna Esposito, Bahaa Abu Raya, Eugenio Baraldi, Katie Flanagan, Federico Martinon Torres, Maria Tsolia, Stefan Zielen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Respiratory syncytial virus (RSV) causes a spectrum of respiratory illnesses in infants and young children that may lead to hospitalizations and a substantial number of outpatient visits, which result in a huge economic and healthcare burden. Most ho
Externí odkaz:
https://doaj.org/article/f505d299dd374b9c811f6b9f6659720a
Autor:
Ruth P Duecker, Ines De Mir Messa, Silvija‐Pera Jerkic, Annalena Kochems, Gabriele Gottwald, Antonio Moreno‐Galdó, Martin Rosewich, Lucia Gronau, Stefan Zielen, Andreas Geburtig‐Chiocchetti, Hermann Kreyenberg, Ralf Schubert
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 2, Pp n/a-n/a (2022)
Abstract Objectives Post‐infectious bronchiolitis obliterans (PiBO) is a rare, chronic disease initiated by severe infection and followed by perpetuating inflammation and obliteration of the small airways. MicroRNAs (miRNAs) have been proposed to p
Externí odkaz:
https://doaj.org/article/ff7f4febafca454bbbf0f03f4ada857c
Autor:
Andrew Menzies-Gow, Michael E Wechsler, Christopher E Brightling, Stephanie Korn, Jonathan Corren, Elliot Israel, Geoffrey Chupp, Artur Bednarczyk, Sandhia Ponnarambil, Scott Caveney, Gun Almqvist, Monika Gołąbek, Linda Simonsson, Kaitlyn Lawson, Karin Bowen, Gene Colice, Jorge Lima Hetzel, Jussara Fiterman, Adelmir Souza Machado, Martti Anton Antila, Marina Andrade Lima, Suzana Erico Tanni Minamoto, Daniela Cavalet Blanco, Patricia Gomes de Matos Bezerra, Pierre-Alain Houle, Catherine Lemiere, Lyle S Melenka, Richard Leigh, Patrick Mitchell, Syed Anees, Bonavuth Pek, Guy Chouinard, Amarjit S Cheema, William Ho-Ching Yang, George Philteos, Pascal Chanez, Arnaud Bourdin, Gilles Devouassoux, Camille Taille, Frédéric De Blay, Christophe Leroyer, Antoine Beurnier, Gilles Garcia, Pierre-Olivier Girodet, François-Xavier Blanc, Antoine Magnan, Stéphanie Wanin, Jocelyne Just, Richard Linde, Stefan Zielen, Karin Förster, Christian Geßner, Margret Jandl, Roland Otto Buhl, Marc Oliver Kornmann, Anneliese Linnhoff, Andrea Ludwig-Sengpiel, Martin Ehlers, Tibor Schmoller, Heiner Steffen, Martin Hoffmann, Joachim Kirschner, Olaf Schmidt, Tobias Welte, Hilke Temme, Ori Wand, Amir Bar-Shai, Gabriel Izbicki, Neville Berkman, Gershon Fink, David Shitrit, Yochai Adir, Piotr Kuna, Barbara Rewerska, Ewa Pisarczyk-Bogacka, Oksana Kurbacheva, Sergey L Mikhailov, Maksim Vasilev, Alexander Emelyanov, Siraj Wali, Amr Albanna, Richard van Zyl-Smit, Ismail Abdullah, David Bernhardi, Farzana Hoosen, Elvis Irusen, Ismail Kalla, Deepak Lakha, Essack Mitha, Visvakuren Naidoo, Haylene Nell, Trevenesan Padayachee, Jeevren Reddy, Friedrich Petrick, Eugene van der Walt, Zubar Fazal Ahmed Vawda, Hae-Sim Park, Sang Haak Lee, Mi-Kyeong Kim, Jung-Won Park, You Sook Cho, Byung Jae Lee, Yoon-Seok Chang, Choon-Sik Park, Kwan Ho Lee, Sook Young Lee, HyoungKyu Yoon, Kyoung Hee Sohn, Myung Jae Park, Kyung Hoon Min, Young Joo Cho, Han Ki Park, YongChul Lee, Jaechun Lee, Chau-Chyun Sheu, Chih-Yen Tu, Kang-Yun Lee, Sevim Bavbek, Bilun Gemicioglu, Dane Ediger, Ilkay Koca Kalkan, Nataliia Makieieva, Mykola Ostrovskyy, Yevgeniya Dytyatkovs'ka, Yuriy Mykhaylovych Mostovoy, Kyrylo Lebed, Oleh Yakovenko, Atoya Adams, Timothy Mooring, Louis Torres Jr, Marvin Sexton, Ernest Thompson, Jonathan A Bernstein, Paul Lisi, Christopher M Chappel, Jeremy Cole, Gary I Greenwald, Conigliaro Jones, Ryan Mitchell Klein, David N Pham, Selwyn Spangenthal, Steven F Weinstein, Hugh H Windom, Neil L Kao, Mila A Leong, Vinay Mehta, Wendy C Moore, Saligrama Bhat, Bassil Aish, Steven M Meltzer, Mark H Moss, Edward M Kerwin, John Palsted Delgado, Gregg Hudson Lucksinger, Charles A Thompson, Sady A Alpizar, Sanjay Virgi Vadgama, Zahid Zafar, Joshua S Jacobs, NJira Lugogo, Neal Jain, Lawrence D Sher, Nabil S Andrawis, David Fuentes, Eric Jason Boren, Erika G Gonzalez, Neetu Talreja, Sheharyar Sandy Durrani, Sudhir Sekhsaria, Samuel DeLeon, Mayank Shukla, Martha M Totszollosy Tarpay, Faisal Fakih, Golda Hudes, Jeffrey P Tillinghast, Phillip E Korenblat, Kartik Shenoy, Loretta Que, Shahrukh Ahmad Kureishy, Fred Chukwuemeka Umeh, Vinh Nhu Nguyen, Hanh Thi Chu, Thuy Thi Dieu Nguyen
Publikováno v:
The Lancet Respiratory Medicine. 11:425-438