Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Stefan, Verhoog"'
Autor:
Véronique Gouverneur, Jiang Wu, Long Lu, Qilong Shen, Stefan Verhoog, Thomas C. Wilson, Qunchao Zhao
Publikováno v:
Angewandte Chemie. 131:2435-2439
A highly reactive electrophilic bromodifluoromethylthiolating reagent, α-cumyl bromodifluoro-methanesulfenate 1, was prepared to allow for direct bromodifluoromethylthiolation of aryl boron reagents. This coupling reaction takes place under copper c
Autor:
Wade Winton, Benjamin L. Viglianti, Melanie S. Sanford, Stefan Verhoog, Peter Scott, Allen F. Brooks
Publikováno v:
Chemical Communications. 55:6361-6364
A simple technique for the preparation of [18F]HF has been developed and applied to the generation of an [18F]FeF species for opening sterically hindered epoxides. This method has been successfully employed to prepare four drug-like molecules, includ
Autor:
Patricia Zhang Musacchio, Ian W. Davies, Robert W Pipal, Stefan Verhoog, Talakad G. Lohith, David Hesk, Alexander Schmitz, Thomas J. A. Graham, Sumei Ren, Hsiaoju S Lee, Eric D. Hostetler, David W. C. MacMillan, Kenneth T Stout, Liza Gantert
Publikováno v:
Nature
Positron emission tomography (PET) radioligands (radioactively labelled tracer compounds) are extremely useful for in vivo characterization of central nervous system drug candidates, neurodegenerative diseases and numerous oncology targets1. Both tri
Autor:
Damien Mahaut, Patrick G. Isenegger, Thomas C. Wilson, Véronique Gouverneur, Jeroen B. I. Sap, Rebekka Hueting, Nicholas J. Taylor, Florian Guibbal, Sean Preshlock, Bart Cornelissen, Stefan Verhoog, Anna Pacelli
Positron emission tomography (PET) is a diagnostic nuclear imaging modality that relies on automated protocols to prepare agents labeled with a positron-emitting radionuclide (e.g., 18F). In recent years, new reactions have appeared for the 18F-label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafac54e928f569bf5dc415170a7a4f1
https://doi.org/10.1038/s41596-020-0295-7
https://doi.org/10.1038/s41596-020-0295-7
Autor:
Stefan Verhoog, Thomas C. Wilson, Jane K. Sosabowski, Véronique Gouverneur, Giulia Boscutti, Christophe Plisson, Florian Guibbal, Jan Passchier, Sharon Ashworth, Mateusz Imiołek, Michael J. Tilby, Sven Macholl, Benjamin G. Davis, Choon Wee Kee, Adeline W. J. Poh, Bart Cornelissen, Osman Tack, Juliette Chupin, Michael C. Willis, Patrick G. Isenegger, Roxana Kashani
Publikováno v:
Journal of the American Chemical Society
18F labeling strategies for unmodified peptides with [18F]fluoride require 18F-labeled prosthetics for bioconjugation more often with cysteine thiols or lysine amines. Here we explore selective radical chemistry to target aromatic residues applying C
Autor:
Liza Gantert, Patricia Zhang Musacchio, Eric D. Hostetler, Ian W. Davies, David W. C. MacMillan, Talakad G. Lohith, David Hesk, Thomas H. Graham, Alexander Schmitz, Stefan Verhoog, Sumei Ren, Hsiaoju Lee
Publikováno v:
Nuclear Medicine and Biology. :S13
Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands
Autor:
Matthew Tredwell, Michael Schedler, Christophe Genicot, Joël Mercier, Véronique Gouverneur, Sean Preshlock, Enrico Emer, Stefan Verhoog, Nicholas J. Taylor
Publikováno v:
Journal of the American Chemical Society. 139:8267-8276
Molecules labeled with fluorine-18 ((18)F) are used in positron emission tomography to visualize, characterize and measure biological processes in the body. Despite recent advances in the incorporation of (18)F onto arenes, the development of general
Autor:
Florian, Guibbal, Patrick G, Isenegger, Thomas C, Wilson, Anna, Pacelli, Damien, Mahaut, Jeroen B I, Sap, Nicholas J, Taylor, Stefan, Verhoog, Sean, Preshlock, Rebekka, Hueting, Bart, Cornelissen, Véronique, Gouverneur
Publikováno v:
Nature protocols. 15(4)
Positron emission tomography (PET) is a diagnostic nuclear imaging modality that relies on automated protocols to prepare agents labeled with a positron-emitting radionuclide (e.g.
Autor:
Stefan, Verhoog, Allen F, Brooks, Wade P, Winton, Benjamin L, Viglianti, Melanie S, Sanford, Peter J H, Scott
Publikováno v:
Chem Commun (Camb)
A simple technique for the preparation of [(18)F]HF has been developed and applied to the generation of an [(18)F]FeF species for opening sterically hindered epoxides. This method has been successfully employed to prepare four drug-like molecules, in
Autor:
Jiang, Wu, Qunchao, Zhao, Thomas C, Wilson, Stefan, Verhoog, Long, Lu, Véronique, Gouverneur, Qilong, Shen
Publikováno v:
Angewandte Chemie (International ed. in English). 58(8)
A highly reactive electrophilic bromodifluoromethylthiolating reagent, α-cumyl bromodifluoro-methanesulfenate 1, was prepared to allow for direct bromodifluoromethylthiolation of aryl boron reagents. This coupling reaction takes place under copper c