Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Stefan, Sturm"'
Autor:
Stefan Sturm
Publikováno v:
Electronic Journal of Differential Equations, Vol 2015, Iss 100,, Pp 1-25 (2015)
We study a Cauchy-Dirichlet problem with homogeneous boundary conditions on the parabolic boundary of a space-time cylinder for degenerate porous medium type equations with low order terms and a non-negative, finite Radon measure on the right-hand
Externí odkaz:
https://doaj.org/article/36c1a180d7a145f590c26f1dc4e8baa3
Autor:
Patanjali Ravva, Annabelle Lemenuel-Diot, Rajinder Bhardwaj, Clare Nasmyth-Miller, Steve Dang, Patrick F. Smith, Elke Zwanziger, Stefan Sturm, Kashyap Patel, Leonid Gibiansky
Publikováno v:
British Journal of Clinical Pharmacology
Aim Pharmacologic effects were analysed to determine a dose recommendation for oseltamivir in immunocompromised (IC) adults with influenza. Methods Quantitative clinical pharmacology methods were applied to data from 160 adult IC patients (aged 18-78
Autor:
Barry Clinch, Stefan Sturm, Elke Zwanziger, Leonid Gibiansky, Paul Grimsey, Patanjali Ravva, Neil Parrott, Rajinder Bhardwaj
Publikováno v:
Clinical Pharmacology and Therapeutics
A mechanistic population‐pharmacokinetic model was developed to predict oseltamivir exposures in neonates and infants accounting for physiological changes during the first 2 years of life. The model included data from 13 studies, comprising 436 sub
Autor:
Leonid Gibiansky, Jules Hernández-Sánchez, Sebastien Jolivet, Annabelle Lemenuel-Diot, Rajinder Bhardwaj, Stefan Sturm, Timothy Knab, Patanjali Ravva, Eric Burroughs Jordie, Elke Zwanziger, Clare Nasmyth-Miller
Publikováno v:
British journal of clinical pharmacologyREFERENCES. 88(3)
AIMS To optimise the dosing regimen of oseltamivir for immunocompromised (IC) paediatric patients (
Publikováno v:
Nonlinear Analysis. 185:49-67
We investigate the relations between different regularity assumptions in the definition of weak solutions and supersolutions to the porous medium equation. In particular, we establish the equivalence of the conditions u m ∈ L loc 2 ( 0 , T ; H loc
Autor:
Stefan Sturm
Publikováno v:
manuscripta mathematica. 157:295-322
On a cylindrical domain $$E_T$$ , we consider doubly nonlinear parabolic equations, whose prototype is $$\partial _t u - \mathrm{div}(|u|^{m-1}|Du|^{p-2}Du) = \mu ,$$ where $$\mu $$ is a non-negative Radon measure having finite total mass $$\mu (E_T)
Autor:
Lothar Lindemann, Giuseppe Palermo, Michael Derks, Marie-Laure Delporte, Stefan Sturm, Robert James Weikert, Salah Hadi, Georg Jaeschke, Scott Schobel
Publikováno v:
British Journal of Clinical Pharmacology. 84:445-455
SummaryAIM The objectives of this first-in-human study were to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, and to determine the maximum tolerated dose (MTD) of single ascending oral doses of RG7342, a positive alloste
Autor:
Stefan Sturm
Publikováno v:
Journal of Mathematical Analysis and Applications. 455:842-863
We deal with a Cauchy–Dirichlet problem with homogeneous boundary conditions on the parabolic boundary of a space–time cylinder for doubly nonlinear parabolic equations, whose prototype is ∂ t u − div ( | u | m − 1 | D u | p − 2 D u ) = f
Autor:
Stefan Sturm
Publikováno v:
Annales Academiae Scientiarum Fennicae Mathematica. 42:931-962
Autor:
Markus Niggli, Christophe Schmitt, Mylene Giraudon, Nathalie Lambert, Bernhard Mangold, Stefan Sturm, Jochen Brumm
Publikováno v:
Diabetes, Obesity and Metabolism. 19:537-544
Aim To evaluate single-dose pharmacokinetics and tolerability of taspoglutide in people with varying degrees of renal impairment and matched healthy participants. Methods Participants in the present study were people with mild renal impairment (n = 1