Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Stefan, Sperl"'
1
Akademický článek
Safety and Tolerability of KIO-101 Eye Drops in Healthy Volunteers and Patients with Ocular Surface Disease—A Phase I Study
Autor: Doreen Schmidl, Nikolaus Hommer, Martin Kallab, Andreas Schlatter, Clemens Nadvornik, Franz Obermayr, Stefan Sperl, Eric J. Daniels, Gerhard Garhöfer
Publikováno v: Pharmaceutics, Vol 16, Iss 3, p 367 (2024)
Purpose: Inhibitors of dihydroorotate dehydrogenase (DHODH) have been found to be potent anti-inflammatory agents. Recently, a topical formulation (KIO-101 eye drops) of a DHODH inhibitor has been developed. The aim of the present study was to evalua
Externí odkaz: https://doaj.org/article/759a9169e30740b5bc7a7f0f908c78c7
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2
Akademický článek
A new small molecule DHODH-inhibitor [KIO-100 (PP-001)] targeting activated T cells for intraocular treatment of uveitis — A phase I clinical trial
Autor: Stephan Thurau, Christoph M. E. Deuter, Arnd Heiligenhaus, Uwe Pleyer, Joachim Van Calster, Talin Barisani-Asenbauer, Franz Obermayr, Stefan Sperl, Romana Seda-Zehetner, Gerhild Wildner
Publikováno v: Frontiers in Medicine, Vol 9 (2022)
Uveitis is a T cell-mediated, intraocular inflammatory disease and one of the main causes of blindness in industrialized countries. There is a high unmet need for new immunomodulatory, steroid-sparing therapies, since only ciclosporin A and a single
Externí odkaz: https://doaj.org/article/91d5150c3bf84380ba8db090b62ca8f5
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3
Akademický článek
Intraocular DHODH-inhibitor PP-001 suppresses relapsing experimental uveitis and cytokine production of human lymphocytes, but not of RPE cells
Autor: Maria Diedrichs-Möhring, Sandy Niesik, Claudia S. Priglinger, Stephan R. Thurau, Franz Obermayr, Stefan Sperl, Gerhild Wildner
Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background Uveitis is a potentially blinding inflammatory disease of the inner eye with a high unmet need for new therapeutic interventions. Here, we wanted to investigate the suppressive effect of the intraocular application of the small mo
Externí odkaz: https://doaj.org/article/35027cc6f0494c0a811224b2e45aa2f2
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7
İnsanın Boş Özü: Hadis Literatüründe ve Klasik Arap Edebinde Etik ve Estetik
Autor: Suat Koca, Stefan Sperl
Publikováno v: Volume: 19, Issue: 1 509-546
Hitit Üniversitesi İlahiyat Fakültesi Dergisi
Classical Arabic Ḥadīth literature is largely composed of micro-narratives recording the sayings and deeds of the Prophet Muḥammad. This study seeks to examine their literary form by focusing on selected examples listed in the canonical Ḥadīt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fa5781a2709fd7f972fadfe42e89b2
https://doi.org/10.14395/hititilahiyat.674885
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8
Stages of Ascent: Neoplatonic Affinities in Classical Arabic Poetry
Autor: Stefan Sperl
This chapter argues that the Arabic poetic tradition possesses certain structural, thematic and prosodic features which were combined with the Qur’anic message in order to give expression to notions of the soul’s ascent which may be recognised as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1666e30a02ecb98bf45b545066c3879a
https://doi.org/10.5871/bacad/9780197267257.003.0003
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9
Introduction: ‘A Thing All Living Faces’
Autor: Stefan Sperl, Yorgos Dedes
The introduction begins by situating the book against the background of the identity conflicts which have radicalized the political debate in Europe and beyond. It explains the objective of the work as aiming to highlight the common heritage shared b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a13da7c10c9a6e591945cbe8a56c9731
https://doi.org/10.5871/bacad/9780197267257.003.0001
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10
The Qurʾan and Arabic Poetry
Autor: Stefan Sperl
This chapter reviews recent scholarship on the interface between the Qur’an and Arabic Poetry, from pre-Islamic times to the modern period. It shows that Arabic poetry has for long been engaged in an inter-textual dialogue with the Qur’an which h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa7f58f65791f31e4b5d63340dedb48
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