Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stefan, Passlick"'
Publikováno v:
eLife, Vol 13 (2024)
Ischemia leads to a severe dysregulation of glutamate homeostasis and excitotoxic cell damage in the brain. Shorter episodes of energy depletion, for instance during peri-infarct depolarizations, can also acutely perturb glutamate signaling. It is le
Externí odkaz:
https://doaj.org/article/5cfb633bde8249dca841a174ef157cc7
Autor:
Cátia Domingos, Franziska E. Müller, Stefan Passlick, Dagmar Wachten, Evgeni Ponimaskin, Martin K. Schwarz, Susanne Schoch, André Zeug, Christian Henneberger
Publikováno v:
Cells, Vol 12, Iss 2, p 331 (2023)
Structural changes of astrocytes and their perisynaptic processes occur in response to various physiological and pathophysiological stimuli. They are thought to profoundly affect synaptic signalling and neuron-astrocyte communication. Understanding t
Externí odkaz:
https://doaj.org/article/5a44943070434b2c8ecc0c48ef588060
Publikováno v:
Cells, Vol 11, Iss 19, p 3150 (2022)
The concept of the tripartite synapse describes the close interaction of pre- and postsynaptic elements and the surrounding astrocyte processes. For glutamatergic synapses, it is established that the presence of astrocytic processes and their structu
Externí odkaz:
https://doaj.org/article/ae8e406ed8f147f8b0883cd7958ebb26
Autor:
Stefan Hardt, Dario Tascio, Stefan Passlick, Aline Timmermann, Ronald Jabs, Christian Steinhäuser, Gerald Seifert
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Synaptic and axonal glutamatergic signaling to NG2 glia in white matter is critical for the cells’ differentiation and activity dependent myelination. However, in gray matter the impact of neuron-to-NG2 glia signaling is still elusive, because most
Externí odkaz:
https://doaj.org/article/f5ed9c22b65242efab86a5cf20ba8f2b
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
High-affinity, Na+-dependent glutamate transporters are the primary means by which synaptically released glutamate is removed from the extracellular space. They restrict the spread of glutamate from the synaptic cleft into the perisynaptic space and
Externí odkaz:
https://doaj.org/article/f089a72e10c548b89c684added8fb4fa
Autor:
Michel K. Herde, Kirsten Bohmbach, Cátia Domingos, Natascha Vana, Joanna A. Komorowska-Müller, Stefan Passlick, Inna Schwarz, Colin J. Jackson, Dirk Dietrich, Martin K. Schwarz, Christian Henneberger
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108182- (2020)
Summary: Synaptically released glutamate is largely cleared by glutamate transporters localized on perisynaptic astrocyte processes. Therefore, the substantial variability of astrocyte coverage of individual hippocampal synapses implies that the effi
Externí odkaz:
https://doaj.org/article/db94c07843ce4150be52cf0a045b7c15
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187732 (2017)
Neuronal cells receive a variety of excitatory and inhibitory signals which they process to generate an output signal. In order to study the interaction between excitatory and inhibitory receptors with exogenously applied transmitters in the same pre
Externí odkaz:
https://doaj.org/article/53909d172a064b8490229574dd48f919
Autor:
Mitsuhiro Oishi, Stefan Passlick, Yoshihiko Yamazaki, Miyuki Unekawa, Ruka Adachi, Mayumi Yamada, Itaru Imayoshi, Yoshifumi Abe, Christian Steinhäuser, Kenji F. Tanaka
Publikováno v:
GliaREFERENCES. 71(2)
Nerve/glial antigen 2 (NG2) is a protein marker of NG2 glia and mural cells, and NG2 promoter activity is utilized to target these cells. However, the NG2 promoter cannot target NG2 glia and mural cells separately. This has been an obstacle for NG2 g
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Autor:
Christian Steinhäuser, Hidekazu Tanaka, Stefan Passlick, Hikaru Hashitani, Retsu Mitsui, Kenji F. Tanaka, Mitsuhiro Oishi, Ronald Jabs
Publikováno v:
British Journal of Pharmacology. 178:1073-1094
BACKGROUND AND PURPOSE While the bladder vasculature is considered as a target of PDE5 inhibitors to improve bladder storage dysfunctions, its characteristics are largely unknown. Thus, the functional and morphological properties of arteries/arteriol