Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stefan, Mundwiler"'
Autor:
Pius August Schubiger, Roger Schibli, Holger Moch, Alexander Knuth, Jakob Nüesch, Roger Alberto, Martin Küenzi, Susanne Kunze, Stefan Mundwiler, Dave R. van Staveren, Niklaus G. Schaefer, Hansjörg Treichler, Robert Waibel
Supplementary Table 1 from New Derivatives of Vitamin B12 Show Preferential Targeting of Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a929c3171851b6f5f06d5ff13ee2239
https://doi.org/10.1158/0008-5472.22376516
https://doi.org/10.1158/0008-5472.22376516
Autor:
Pius August Schubiger, Roger Schibli, Holger Moch, Alexander Knuth, Jakob Nüesch, Roger Alberto, Martin Küenzi, Susanne Kunze, Stefan Mundwiler, Dave R. van Staveren, Niklaus G. Schaefer, Hansjörg Treichler, Robert Waibel
Supplementary Table 2 from New Derivatives of Vitamin B12 Show Preferential Targeting of Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fa1e1485b05f456a435a4bf84d4ca9
https://doi.org/10.1158/0008-5472.22376513.v1
https://doi.org/10.1158/0008-5472.22376513.v1
Publikováno v:
CHIMIA, Vol 61, Iss 4 (2007)
The cisplatin adduct of vitamin B12, cis-[PtCl(NH3)2B12]+ (1) reacts with dansyl-imidazole to form cis-[Pt(dansyl-imidazole)(NH3)2B12] (2). In a spectroelectrochemical assay, Co(III) in 2 was reduced to Co(II) under concomitant release of the Pt(II)
Externí odkaz:
https://doaj.org/article/b28525576dc44559b1fe25864429585b
Publikováno v:
CHIMIA, Vol 57, Iss 4 (2003)
A new method for 99mTc-labeling using solid-phase technology is described. It allows the separation of unlabeled from labeled bioactive molecules by simple filtration. The procedure is based on a site-specific C–N bond cleavage reaction initiated b
Externí odkaz:
https://doaj.org/article/3bb6b7c31097416bb5a80f3917ad9e65
Autor:
Stefan Mundwiler, Roger Alberto, Bernhard Spingler, Pilar Ruiz-Sánchez, Nicole R. Buan, Jorge C. Escalante-Semerena
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 13:335-347
Aiming at the use of vitamin B12 as a drug delivery carrier for cytotoxic agents, we have reacted vitamin B12 with trans-[PtCl(NH3)2(H2O)]+, [PtCl3(NH3)](-) and [PtCl4](2-). These Pt(II) precursors coordinated directly to the Co(III)-bound cyanide, g
Publikováno v:
European Journal of Inorganic Chemistry. 2007:2641-2647
The acid hydrolysis of natural vitamin B-12 yields several products in which the acetamide or propionamide side chains on the corrin framework are converted into the corresponding acids. These acids can be derivatised with further functionalities. We
Publikováno v:
Nuclear Medicine and Biology. 32:473-484
[(Methyl-pyridin-2-ylmethyl-amino)-methyl]-phosphonic acid is a new bifunctional chelator for the fac-[(99m)Tc(CO(3))](+) core which can be linked to biomolecules via formation of phosphonic acid esters. Its synthesis and the coupling to model alcoho
Autor:
Stefan Mundwiler, Roger Alberto, Katalin Bodo, Gabor Andocs, Lajos Balogh, Kirstin Ortner, Bernhard Spingler, Pascal Häfliger
Publikováno v:
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 35:27-34
Bifunctional chelating molecules linking the fac‐[99mTc(CO)3]+ core with targeting biomolecules are required for the development of specific diagnostic radiopharmaceuticals. Diethylenetriamine (1) and N‐(pyridin‐2‐ylmethyl)ethane‐1,2‐diam
Publikováno v:
Journal of Organometallic Chemistry. 689:4803-4810
In this work, histidine derivatives bearing an acetic acid or a propyl amine substituent on the N e -atom are conjugated to the b -acid, c -acid and d -acid moiety of cyanocobalamin (vitamin B12) via amide formation. Four different derivatives were p
Publikováno v:
Chem. Commun.. 47:403-405
By applying four different acid derivatives of vitamin B(12), we demonstrate that the H-bonding pattern and the electrostatic environment provided by each side chain of the corrin ring are crucial for the correct structural rearrangement of the btuB