Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Stefan, Mergler"'
Autor:
Loreena Rech, Tina Dietrich-Ntoukas, Peter S. Reinach, Tobias Brockmann, Uwe Pleyer, Stefan Mergler
Publikováno v:
Cells, Vol 13, Iss 16, p 1329 (2024)
The conjunctiva has immune-responsive properties to protect the eye from infections. Its innate immune system reacts against external pathogens, such as fungi. The complement factor C5a is an important contributor to the initial immune response. It i
Externí odkaz:
https://doaj.org/article/4233c55cb89f4d3f9472f31dea61d5c3
Autor:
Jennifer Donau, Huan Luo, Iiris Virta, Annett Skupin, Margarita Pushina, Jana Loeffler, Frauke V. Haertel, Anupam Das, Thomas Kurth, Michael Gerlach, Dirk Lindemann, Peter S. Reinach, Stefan Mergler, Monika Valtink
Publikováno v:
Membranes, Vol 12, Iss 3, p 281 (2022)
The functional contribution of transient receptor potential vanilloid 4 (TRPV4) expression in maintaining human corneal endothelial cells (HCEC) homeostasis is unclear. Accordingly, we determined the effects of TRPV4 gene and protein overexpression o
Externí odkaz:
https://doaj.org/article/62217a0e5400493ab9c9ac586cf5c0f0
Autor:
Ersal Türker, Fabian Garreis, Noushafarin Khajavi, Peter S. Reinach, Pooja Joshi, Tobias Brockmann, Alexander Lucius, Nina Ljubojevic, Elizabeth Turan, Drew Cooper, Felix Schick, Rob Reinholz, Uwe Pleyer, Josef Köhrle, Stefan Mergler
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
This study was undertaken to determine if crosstalk among the transient receptor potential (TRP) melastatin 8 (TRPM8), TRP vanilloid 1 (TRPV1), and vascular endothelial growth factor (VEGF) receptor triad modulates VEGF-induced Ca2+ signaling in huma
Externí odkaz:
https://doaj.org/article/9910bc894286499aa43353241e644f1d
Autor:
Lia Walcher, Clara Budde, Arina Böhm, Peter S. Reinach, Priyavathi Dhandapani, Nina Ljubojevic, Markus W. Schweiger, Henriette von der Waydbrink, Ilka Reimers, Josef Köhrle, Stefan Mergler
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
In human uveal melanoma (UM), tumor enlargement is associated with increases in aqueous humor vascular endothelial growth factor-A (VEGF-A) content that induce neovascularization. 3-Iodothyronamine (3-T1AM), an endogenous thyroid hormone metabolite,
Externí odkaz:
https://doaj.org/article/d316075576f345ed8a01cf2ce927edc5
Autor:
Julia Bräunig, Stefan Mergler, Sabine Jyrch, Carolin S. Hoefig, Mark Rosowski, Jens Mittag, Heike Biebermann, Noushafarin Khajavi
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
3-Iodothyronamine (3-T1AM) is an endogenous thyroid hormone metabolite. The profound pharmacological effects of 3-T1AM on energy metabolism and thermal homeostasis have raised interest to elucidate its signaling properties in tissues that pertain to
Externí odkaz:
https://doaj.org/article/6b4fa2fd5eb64453909708924b265e1a
Autor:
Priyavathi Sureshkumar, Robson Augusto Souza dos Santos, Natalia Alenina, Stefan Mergler, Michael Bader
Publikováno v:
Peptides. 165:171010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de88b703ffc36c11cae01464f0dd984a
https://doi.org/10.1016/j.peptides.2023.171010
https://doi.org/10.1016/j.peptides.2023.171010
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
The decarboxylated and deiodinated thyroid hormone (TH) derivative, 3-iodothyronamine (3-T1AM), is suggested to be involved in energy metabolism and thermoregulation. G protein-coupled receptors (GPCRs) are known as the main targets for 3-T1AM; howev
Externí odkaz:
https://doaj.org/article/211da0dbf5794d49ab231f188cd4a783
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 3, Pp 790-803 (2014)
Background/Aims: Ocular surface health depends on conjunctival epithelial (HCjE) layer integrity since it protects against pathogenic infiltration and contributes to tissue hydration maintenance. As the same increases in tear film hyperosmolarity des
Externí odkaz:
https://doaj.org/article/7b76c4953cc146c1bc1ac278d7bece86
Autor:
Stefan Mergler, Srujan Kumar Dondapati, Dennis Bräuer, Stefan Kubick, Doreen A. Wüstenhagen, Priyavathi Dhandapani, Anne Zemella
Publikováno v:
RSC Advances. 11:16285-16296
Calcium imaging is an important functional tool for analysing ion channels, transporters and pumps for drug screening in living cells. Depicted eukaryotic cell-free systems utilize microsomes, derived from the endoplasmic reticulum to incorporate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b5300aa7eac87f8a5735238ddc2507
https://doi.org/10.1039/d0ra08397f
https://doi.org/10.1039/d0ra08397f
Autor:
Uwe Pleyer, Stefan Mergler
Publikováno v:
Klinische Monatsblätter für Augenheilkunde. 237:637-643
ZusammenfassungFür eine optimale visuelle Funktion ist eine Augenoberfläche mit einem vitalen Epithelverband und stabilen Tränenfilm erforderlich. Eine Vielzahl von endogenen und externen Faktoren kann die empfindliche Homöostase der Augenoberfl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12de9341295cb93eb5e06dd830fc9b31
https://doi.org/10.1055/a-1120-8754
https://doi.org/10.1055/a-1120-8754