Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Stefan, Hettwer"'
Publikováno v:
Cosmetics, Vol 9, Iss 5, p 97 (2022)
Nowadays, consumers’ well-being plays a decisive role in the purchase of cosmetic products. Although factors influencing consumers’ well-being are very subjective, companies strive to develop their products in such a way that a positive effect is
Externí odkaz:
https://doaj.org/article/f333d5dd1e8b48e8ab7efc11118ed482
Autor:
Sally Spendiff, Rachel Howarth, Grace McMacken, Tracey Davey, Kaitlyn Quinlan, Emily O'Connor, Clarke Slater, Stefan Hettwer, Armin Mäder, Andreas Roos, Rita Horvath, Hanns Lochmüller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Introduction: Congenital myasthenic syndromes (CMS) are a diverse group of inherited neuromuscular disorders characterized by a failure of synaptic transmission at the neuromuscular junction (NMJ). CMS often present early with fatigable weakness and
Externí odkaz:
https://doaj.org/article/abdd85adee9246eda39df3320d66f035
Autor:
Dominik Steubl, Marcel Roos, Stefan Hettwer, Susanne Angermann, Ming Wen, Christoph Schmaderer, Peter Luppa, Uwe Heemann, Lutz Renders
Publikováno v:
Kidney & Blood Pressure Research, Vol 41, Iss 2, Pp 175-185 (2016)
Background/Aims: This study compares the peritoneal elimination of the low-molecular-weight-protein (LMWP) C-terminal agrin fragment (tCAF, size 22 kDa), a promising biomarker for kidney function, in continuous cycling peritoneal dialysis (CCPD) and
Externí odkaz:
https://doaj.org/article/1c71f085556747e2a4061072423c3ef7
Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy
Autor:
Marina Boido, Elena De Amicis, Valeria Valsecchi, Marco Trevisan, Ugo Ala, Markus A. Ruegg, Stefan Hettwer, Alessandro Vercelli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Spinal muscular atrophy (SMA) is a pediatric genetic disease, characterized by motor neuron (MN) death, leading to progressive muscle weakness, respiratory failure, and, in the most severe cases, to death. Abnormalities at the neuromuscular junction
Externí odkaz:
https://doaj.org/article/d2735a6d2bf2470b865b9ab8fa12ae0d
Autor:
Emily O’Connor, George Cairns, Sally Spendiff, David Burns, Stefan Hettwer, Armin Mäder, Juliane Müller, Rita Horvath, Clarke Slater, Andreas Roos, Hanns Lochmüller
Publikováno v:
Cells, Vol 8, Iss 8, p 848 (2019)
Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterised by impaired function of the neuromuscular junction (NMJ). This is due to defects in one of the many proteins associated with the NMJ. In three patients with
Externí odkaz:
https://doaj.org/article/58e2aa45b59e444297f9c29f803bb62e
Publikováno v:
International Journal of Cosmetic Science
Objective The circadian rhythm was set into focus by awarding the Nobel Price of Physiology/Medicine to Jeffrey Hall, Michael Rosbash and Michael Young in late 2017. Numerous publications elucidated the molecular mechanisms driving the circadian bior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e431431684559736c93e10e7813a5a46
http://europepmc.org/articles/PMC7496414
http://europepmc.org/articles/PMC7496414
Autor:
Arezoo Daryadel, Monika Haubitz, Marta Figueiredo, Dominik Steubl, Marcel Roos, Armin Mäder, Stefan Hettwer, Carsten A Wagner
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157905 (2016)
Agrin, a multidomain proteoglycan and neurotrypsin, a neuronal serine protease, are important for forming (neuromuscular) synapses. Proteolytical activity of neurotrypsin produces a C-terminal fragment of agrin, termed CAF, of approximately 22 kDA mo
Externí odkaz:
https://doaj.org/article/7be8a82181414ba6bad6c43e93420e1e
Autor:
Vasilios Devetzis, Arezoo Daryadel, Stefanos Roumeliotis, Marios Theodoridis, Carsten A Wagner, Stefan Hettwer, Uyen Huynh-Do, Passadakis Ploumis, Spyridon Arampatzis
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143524 (2015)
Diabetes is the leading cause of CKD in the developed world. C-terminal fragment of agrin (CAF) is a novel kidney function and injury biomarker. We investigated whether serum CAF predicts progression of kidney disease in type 2 diabetics.Serum CAF le
Externí odkaz:
https://doaj.org/article/b077783db2d142f983f80894896965cb
Autor:
Stefan Hettwer, Shuo Lin, Stefan Kucsera, Monika Haubitz, Filippo Oliveri, Ruggero G Fariello, Markus A Ruegg, Jan W Vrijbloed
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88739 (2014)
Treatment of neuromuscular diseases is still an unsolved problem. Evidence over the last years strongly indicates the involvement of malformation and dysfunction of neuromuscular junctions in the development of such medical conditions. Stabilization
Externí odkaz:
https://doaj.org/article/00e9738327334c9d8d21e4265f442ff8
Publikováno v:
International Journal of Cosmetic Science. 39:379-385
Objective Blocking the TRPV1 receptor is an interesting approach for the treatment of sensitive skin. Here we investigated the potential of grifolin derivatives from Albatrellus ovinus to act as TRPV1 receptor blockers and their potential to serve as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a076c7c2e2fabe323eb51fc3342a0f
https://doi.org/10.1111/ics.12385
https://doi.org/10.1111/ics.12385