Zobrazeno 1 - 10 of 139 pro vyhledávání: '"Stefan, Herzig"'
1
Akademický článek
Autism-associated mutations in the CaVβ2 calcium-channel subunit increase Ba2+-currents and lead to differential modulation by the RGK-protein Gem
Autor: Patrick Despang, Sarah Salamon, Alexandra F. Breitenkamp, Elza Kuzmenkina, Stefan Herzig, Jan Matthes
Publikováno v: Neurobiology of Disease, Vol 136, Iss , Pp 104721- (2020)
Voltage-gated calcium-channels (VGCCs) are heteromers consisting of several subunits. Mutations in the genes coding for VGCC subunits have been reported to be associated with autism spectrum disorder (ASD). In a previous study, we identified electrop
Externí odkaz: https://doaj.org/article/1bcec8b5d2ae424db772baae27b7ccc5
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2
Akademický článek
Regulations and practices of structured doctoral education in the life sciences in Germany.
Autor: Daniel Lachmann, Thilo Martius, Julia Eberle, Mareike Landmann, Lena von Kotzebue, Birgit Neuhaus, Stefan Herzig
Publikováno v: PLoS ONE, Vol 15, Iss 7, p e0233415 (2020)
Structured doctoral education is increasingly preferred compared to the individual model. Several science policy organisations give recommendations on how to structure doctoral education. However, there is little research on to what extent these reco
Externí odkaz: https://doaj.org/article/64824707e7d6442abac3d38196876f4c
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7
Akademický článek
The Flex-OeCoS—a Novel Optically Accessible Test Rig for the Investigation of Advanced Combustion Processes under Engine-Like Conditions
Autor: Bruno Schneider, Christian Schürch, Konstantinos Boulouchos, Stefan Herzig, Marc Hangartner, David Humair, Silas Wüthrich, Christoph Gossweiler, Kai Herrmann
Publikováno v: Energies, Vol 13, Iss 7, p 1794 (2020)
A new test rig has been designed, built and commissioned, and is now jointly pursued to facilitate experimental investigations into advanced combustion processes (i.e., dual fuel, multi-mode) under turbulent conditions at high, engine-like temperatur
Externí odkaz: https://doaj.org/article/b4771260cc664acdbef84a12961ccdb9
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9
Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit α2δ-1 with thrombospondin-4
Autor: Frank Zaucke, Mats Paulsson, Wolfram F. Neiss, Cora Fried, Stefan Herzig, Markus Pietsch, Ehab El-Awaad, Jörg Isensee, Jan Matthes, Galyna Pryymachuk, Tim Hucho
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
The α2δ‐1 subunit of voltage-gated calcium channels binds to gabapentin and pregabalin, mediating the analgesic action of these drugs against neuropathic pain. Extracellular matrix proteins from the thrombospondin (TSP) family have been identifie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d767cd3e84169bb5a092e453a6267de2
http://link.springer.com/article/10.1038/s41598-019-52655-y
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10
Single-Channel Resolution of the Interaction between C-Terminal CaV1.3 Isoforms and Calmodulin
Autor: Jan Matthes, Wanchana Jangsangthong, Elza Kuzmenkina, Elena Novikova, Stefan Herzig
Publikováno v: Biophysical Journal. 116:836-846
Voltage-dependent calcium (Ca(V)) 1.3 channels are involved in the control of cellular excitability and pacemaking in neuronal, cardiac, and sensory cells. Various proteins interact with the alternatively spliced channel C-terminus regulating gating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630bbbfdbf9763a1a4cd8754a43117eb
https://doi.org/10.1016/j.bpj.2019.01.025
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