Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Stefan, Hallermann"'
Autor:
Maximilian Ruschig, Jana Nerlich, Marlies Becker, Doris Meier, Saskia Polten, Karla Cervantes-Luevano, Philipp Kuhn, Alexei Fedorovish Licea-Navarro, Stefan Hallermann, Stefan Dübel, Maren Schubert, Jeffrey Brown, Michael Hust
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Poisoning by widow-spider (genus Latrodectus) bites occurs worldwide. The illness, termed latrodectism, can cause severe and persistent pain and can lead to muscle rigidity, respiratory complications, and cardiac problems. It is a global health chall
Externí odkaz:
https://doaj.org/article/acca250bd1834b6da56848fc6ab9dcb0
Autor:
Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Prüss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Geis
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113166- (2023)
Summary: Anti-NMDA receptor autoantibodies (NMDAR-Abs) in patients with NMDAR encephalitis cause severe disease symptoms resembling psychosis and cause cognitive dysfunction. After passive transfer of patients’ cerebrospinal fluid or human monoclon
Externí odkaz:
https://doaj.org/article/45b1c68ea10348b1864a030e56f48820
Publikováno v:
eLife, Vol 12 (2023)
A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.
Externí odkaz:
https://doaj.org/article/1845fa69cc9c41829b1237c94a6da6e5
Autor:
Andreas Ritzau-Jost, Jana Nerlich, Thomas Kaas, Martin Krueger, Timur Tsintsadze, Jens Eilers, Boris Barbour, Stephen M. Smith, Stefan Hallermann
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102168- (2023)
Summary: Direct electrical recordings from conventional boutons in the mammalian central nervous system have proven challenging due to their small size. Here, we provide a protocol for direct whole-cell patch-clamp recordings from small presynaptic b
Externí odkaz:
https://doaj.org/article/0702a5e41bc240968ff26a935aecbf51
Autor:
Jannik M. Buettner, Leonie Sowoidnich, Florian Gerstner, Beatriz Blanco-Redondo, Stefan Hallermann, Christian M. Simon
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The activation of the p53 pathway has been associated with neuronal degeneration in different neurological disorders, including spinal muscular atrophy (SMA) where aberrant expression of p53 drives selective death of motor neurons destined to degener
Externí odkaz:
https://doaj.org/article/321dc4f917a843ec9193915e493bafc3
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101236- (2022)
Summary: Loss of synapses on spinal motor neurons is a major feature of several neurodegenerative diseases; however, analyzing these premotor synapses is challenging because of their small size and high density. This protocol describes confocal and S
Externí odkaz:
https://doaj.org/article/5c9a1436414e48049d126c7e3ab278b2
Publikováno v:
eLife, Vol 10 (2021)
The Ca2+-dependence of the priming, fusion, and replenishment of synaptic vesicles are fundamental parameters controlling neurotransmitter release and synaptic plasticity. Despite intense efforts, these important steps in the synaptic vesicles’ cyc
Externí odkaz:
https://doaj.org/article/5feb4b556d074411b3872d170f03cf59
Autor:
Magdalena Wender, Grit Bornschein, Simone Brachtendorf, Stefan Hallermann, Jens Eilers, Hartmut Schmidt
Publikováno v:
The Journal of Neuroscience. 43:4005-4018
The composition of voltage-gated Ca2+channel (Cav) subtypes that gate action potential (AP)-evoked release changes during the development of mammalian CNS synapses. Cav2.2 and Cav2.3 lose their function in gating-evoked release during postnatal synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c19708409827f73c4021430dc165de1
https://doi.org/10.1523/jneurosci.1279-22.2023
https://doi.org/10.1523/jneurosci.1279-22.2023
Autor:
Stephan Steinke, Toni Kirmann, Eleonora A Loi, Jana Nerlich, Iron Weichard, Philipp Kuhn, Torsten Bullmann, Andreas Ritzau-Jost, Filiz Sila Rizalar, Harald Prüss, Volker Haucke, Christian Geis, Michael Hust, Stefan Hallermann
Publikováno v:
Brain 146(5), 1812-1820 (2023). doi:10.1093/brain/awac497
N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common subtype of autoimmune encephalitis characterized by a complex neuropsychiatric syndrome usually including memory impairment. Patients develop an intrathecal immune response against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a3f874910e28ae5dc4cf7b4e152beb
https://doi.org/10.1093/brain/awac497
https://doi.org/10.1093/brain/awac497
Autor:
Andreas Ritzau-Jost, Timur Tsintsadze, Martin Krueger, Jonas Ader, Ingo Bechmann, Jens Eilers, Boris Barbour, Stephen M. Smith, Stefan Hallermann
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108612- (2021)
Summary: Presynaptic action potential spikes control neurotransmitter release and thus interneuronal communication. However, the properties and the dynamics of presynaptic spikes in the neocortex remain enigmatic because boutons in the neocortex are
Externí odkaz:
https://doaj.org/article/f9340d45cbe140b5800ffb68424b11e0