Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Stefan, Gattenlöhner"'
Autor:
Learta Pervizaj-Oruqaj, Balachandar Selvakumar, Maximiliano Ruben Ferrero, Monika Heiner, Christina Malainou, Rolf David Glaser, Jochen Wilhelm, Marek Bartkuhn, Astrid Weiss, Ioannis Alexopoulos, Biruta Witte, Stefan Gattenlöhner, István Vadász, Rory Edward Morty, Werner Seeger, Ralph Theo Schermuly, Ana Ivonne Vazquez-Armendariz, Susanne Herold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Influenza A virus (IAV) infection mobilizes bone marrow-derived macrophages (BMDM) that gradually undergo transition to tissue-resident alveolar macrophages (TR-AM) in the inflamed lung. Combining high-dimensional single-cell transcriptomics
Externí odkaz:
https://doaj.org/article/78b9668d870244cca6b2f62d7f2fe96b
Autor:
Jörg Kumbrink, Melanie-Christin Demes, Jan Jeroch, Andreas Bräuninger, Kristin Hartung, Uwe Gerstenmaier, Ralf Marienfeld, Axel Hillmer, Nadine Bohn, Christina Lehning, Ferdinand Ferch, Peter Wild, Stefan Gattenlöhner, Peter Möller, Frederick Klauschen, Andreas Jung
Publikováno v:
Pathology and Oncology Research, Vol 30 (2024)
Lung cancer is a paradigm for a genetically driven tumor. A variety of drugs were developed targeting specific biomarkers requiring testing for tumor genetic alterations in relevant biomarkers. Different next-generation sequencing technologies are av
Externí odkaz:
https://doaj.org/article/4cb60bd82d3c4b56863f874dcfbdde4b
Autor:
Kaire Ojasalu, Corinna Brehm, Kristin Hartung, Maximilian Nischak, Florian Finkernagel, Peter Rexin, Andrea Nist, Evangelos Pavlakis, Thorsten Stiewe, Julia M. Jansen, Uwe Wagner, Stefan Gattenlöhner, Andreas Bräuninger, Sabine Müller‐Brüsselbach, Silke Reinartz, Rolf Müller
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 2142-2162 (2020)
A hallmark of ovarian high‐grade serous carcinoma (HGSC) is its early and massive peritoneal dissemination via the peritoneal fluid. It is generally believed that tumor cells must breach the mesothelium of peritoneal organs to adhere to the underly
Externí odkaz:
https://doaj.org/article/55b4db2c834b437d8699ff8790311788
Small extracellular vesicle‐derived miR‐574‐5p regulates PGE2‐biosynthesis via TLR7/8 in lung cancer
Autor:
Julia Donzelli, Eva Proestler, Anna Riedel, Sheila Nevermann, Brigitte Hertel, Andreas Guenther, Stefan Gattenlöhner, Rajkumar Savai, Karin Larsson, Meike J. Saul
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Intercellular communication plays an essential role in lung cancer (LC). One of the major players in cell‐cell‐communication is small extracellular vesicles (sEV). SEV trigger various biological responses by transporting cellular cargo t
Externí odkaz:
https://doaj.org/article/53f975e7d4c147968353f47b2402cb5f
Autor:
Maria Solovey, Ying Wang, Christian Michel, Klaus H. Metzeler, Tobias Herold, Joachim R. Göthert, Volker Ellenrieder, Elisabeth Hessmann, Stefan Gattenlöhner, Andreas Neubauer, Dinko Pavlinic, Vladimir Benes, Oliver Rupp, Andreas Burchert
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background Acute myeloid leukemia (AML) patients with a high allelic burden of an internal tandem duplication (ITD)-mutated FMS-like Tyrosine Kinase-3 (FLT3) have a dismal outcome. FLT3ITD triggers the proliferation of the quiescent hematopo
Externí odkaz:
https://doaj.org/article/97def0ffa83a43c2b02da120ec5c2f94
Autor:
Meghan Riddell, Akiko Nakayama, Takao Hikita, Fatemeh Mirzapourshafiyi, Takuji Kawamura, Ayesha Pasha, Mengnan Li, Mikio Masuzawa, Mario Looso, Tim Steinbacher, Klaus Ebnet, Michael Potente, Tomonori Hirose, Shigeo Ohno, Ingrid Fleming, Stefan Gattenlöhner, Phyu P. Aung, Thuy Phung, Osamu Yamasaki, Teruki Yanagi, Hiroshi Umemura, Masanori Nakayama
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The cell polarity regulator aPKC is associated with cell proliferation but the precise mechanism are unknown. Here, the authors find that aPKC lambda phosphorylates the FoxO1 transcription factor, a gatekeeper of endothelial growth, during both angio
Externí odkaz:
https://doaj.org/article/262aa7beda84463ca8dfda4862f93e83
Autor:
Thomas Karrasch, Bastian Eul, Stefan Gattenlöhner, Dagmar Steiner, Fritz Roller, Winfried Padberg, Andreas Schäffler
Publikováno v:
Die Innere Medizin. 64:393-400
ZusammenfassungEine 69-jährige Patientin und ein 70-jähriger Patient wurden mit rezidivierenden, schweren Hypoglykämien und klinischer Whipple-Trias aufgenommen. Bei der Patientin ließen erhöhte Spiegel an Insulin und C‑Peptid, ein pathologisc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ecea3d09b42a1667c882e415ccca01d
https://doi.org/10.1007/s00108-023-01473-6
https://doi.org/10.1007/s00108-023-01473-6
Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer
Autor:
Karla Rubio, Addi J. Romero-Olmedo, Pouya Sarvari, Guruprasadh Swaminathan, Vikas P. Ranvir, Diana G. Rogel-Ayala, Julio Cordero, Stefan Günther, Aditi Mehta, Birgit Bassaly, Peter Braubach, Malgorzata Wygrecka, Stefan Gattenlöhner, Achim Tresch, Thomas Braun, Gergana Dobreva, Miguel N. Rivera, Indrabahadur Singh, Johannes Graumann, Guillermo Barreto
Publikováno v:
Theranostics. 13:2384-2407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c6f111a6434aaaf7adb435aa91dd991
https://doi.org/10.7150/thno.79493
https://doi.org/10.7150/thno.79493
Autor:
Eric Dietel, Alexander Brobeil, Lucas Delventhal, Claudia Tag, Stefan Gattenlöhner, Monika Wimmer
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216642 (2019)
LDC3/Dynarrestin, an aminothiazole derivative, is a recently developed small molecule, which binds protein tyrosine phosphatase interacting protein 51 (PTPIP51). PTPIP51 interacts with various proteins regulating different signaling pathways leading
Externí odkaz:
https://doaj.org/article/a0b40c45d9ab42c78895b8be38ea8c75
Autor:
Steffen Wagner, Christine Langer, Nora Wuerdemann, Susanne Reiser, Helen Abing, Jörn Pons-Kühnemann, Elena-Sophie Prigge, Magnus von Knebel Doeberitz, Stefan Gattenlöhner, Tim Waterboer, Lea Schroeder, Christoph Arens, Jens Peter Klussmann, Claus Wittekindt
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2167
Background: Human papillomavirus (HPV) status is the most important predictor of survival in oropharyngeal squamous cell carcinoma (OPSCC). In patients with cervical lymph node metastases of squamous cell carcinoma of unknown origin (CUPHNSCC), much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1bb3dcca1f84f1254797cc95dff994