Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Stefan, Fruehauf"'
Autor:
Arndt Stahler, Beeke Hoppe, Il-Kang Na, Luisa Keilholz, Lothar Müller, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Ludwig Fischer von Weikersthal, Eray Goekkurt, Stefan Kasper, Andreas Jay Kind, Annika Kurreck, Annabel Helga Sophie Alig, Swantje Held, Anke Reinacher-Schick, Volker Heinemann, David Horst, Armin Jarosch, Sebastian Stintzing, Tanja Trarbach, Dominik Paul Modest
Publikováno v:
Journal of Clinical Oncology. 41:2975-2987
PURPOSE Consensus molecular subtypes (CMSs) were evaluated as prognostic and predictive biomarkers of patients with RAS wild-type metastatic colorectal cancer (mCRC) receiving fluorouracil and folinic acid (FU/FA) with or without panitumumab (Pmab) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4090842f0cfdc07a52ad6f0761072810
https://doi.org/10.1200/jco.22.02582
https://doi.org/10.1200/jco.22.02582
Autor:
Heike Allgayer, Stefan Fruehauf, W. Jens Zeller, Frederik Wenz, Jörg H. Leupold, Marcus J. Trunk, Jonathan P. Sleeman, Li Li, Stephanie Laufs, Patrick Maier, Doreen Heckmann
PDF file 100K, S2: Generation of CRC cell lines with high expression of CXCR4 and/or CXCR7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ebad16dffac34e000023e2a99bf839
https://doi.org/10.1158/1078-0432.22448880
https://doi.org/10.1158/1078-0432.22448880
Autor:
Heike Allgayer, Stefan Fruehauf, W. Jens Zeller, Frederik Wenz, Jörg H. Leupold, Marcus J. Trunk, Jonathan P. Sleeman, Li Li, Stephanie Laufs, Patrick Maier, Doreen Heckmann
Purpose: In colorectal cancer, increased expression of the CXC chemokine receptor 4 (CXCR4) has been shown to provoke metastatic disease due to the interaction with its ligand stromal cell-derived factor-1 (SDF-1). Recently, a second SDF-1 receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e800917f809f32f97df492e5e799dbc
https://doi.org/10.1158/1078-0432.c.6521499.v1
https://doi.org/10.1158/1078-0432.c.6521499.v1
Autor:
Greta Sommerhäuser, Annika Kurreck, Alexander Beck, Uli Fehrenbach, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Lothar Mueller, Alexander O. Koenig, Ludwig F. v. Weikersthal, Eray Goekkurt, Siegfried Haas, Arndt Stahler, Volker Heinemann, Swantje Held, Annabel H.S. Alig, Stefan Kasper, Sebastian Stintzing, Tanja Trarbach, Dominik P. Modest
In patients with RAS wild-type metastatic colorectal cancer, depth of response (DpR) has gained importance as a novel end-point in clinical trials. We investigated the overall DpR, as well as the prognostic and predictive impact of DpR to induction t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b086806724f1e90f2b063c80d66d4e8
https://www.ncbi.nlm.nih.gov/pubmed/36399909
https://www.ncbi.nlm.nih.gov/pubmed/36399909
Autor:
Swantje Held, David Horst, Meinolf Karthaus, Lothar Müller, Armin Jarosch, Anke Reinacher-Schick, Volker Heinemann, Stefan Kasper, Ludwig Fischer von Weikersthal, Dominik Paul Modest, Annika Kurreck, Stefan Fruehauf, Eray Goekkurt, Karel Caca, Alexander König, Ullrich Graeven, Albrecht Kretzschmar, Siegfried Haas, Tanja Trarbach, A. Stahler, Sebastian Stintzing
PURPOSE The randomized PANAMA trial investigated the efficacy of panitumumab (Pmab) when added to maintenance therapy with fluorouracil and folinic acid (FU/FA) in patients with RAS wild-type metastatic colorectal cancer. METHODS Following first-line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8fb42ee4f57c47ab9457595fbdb084
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118844548
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85118844548
Autor:
Andreas Jay Kind, Dominik Paul Modest, Christine Sers, Soulafa Mamlouk, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Ludwig Fischer Von Weikersthal, Eray Goekkurt, Anke C. Reinacher-Schick, Stefan Kasper, Annika Kurreck, Beeke Hoppe, Swantje Held, Volker Heinemann, David Horst, Armin Jarosch, Sebastian Stintzing, Tanja Trarbach, Arndt Stahler
3536 Background: We evaluated the prognostic and predictive impact of DNA mutations related to anti-EGFR antibody resistance in patients of the PANAMA trial, which compared Panitumumab (Pmab) and FU/FA versus FU/FA maintenance therapy after Pmab-FOLF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b776c55b4ada467fa6cde0db576b8bf6
Autor:
Meinolf Karthaus, Greta Sommerhäuser, Annika Kurreck, Alexander Beck, Uli Fehrenbach, Stefan Fruehauf, Ullrich Graeven, Lothar Müller, Alexander Koenig, Ludwig Fischer von Weikersthal, Eray Goekkurt, Siegfried Haas, Arndt Stahler, Volker Heinemann, Swantje Held, Annabel Helga Sophie Alig, Stefan Kasper, Sebastian Stintzing, Tanja Trarbach, Dominik Paul Modest
Publikováno v:
Journal of Clinical Oncology. 41:127-127
127 Background: Despite molecular selection, patients with RAS wildtype mCRC represent a heterogeneous population, including different metastatic patterns and number of organs involved. We investigated metastatic patterns for their prognostic and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4490199882a418a8f48da145332fa333
https://doi.org/10.1200/jco.2023.41.4_suppl.127
https://doi.org/10.1200/jco.2023.41.4_suppl.127
Autor:
Alexej Ballhausen, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Lothar Mueller, Alexander Koenig, Ludwig Fischer von Weikersthal, Greta Sommerhäuser, Annabel Helga Sophie Alig, Eray Goekkurt, Siegfried Haas, Annika Kurreck, Arndt Stahler, Swantje Held, Anke C. Reinacher-Schick, Stefan Kasper, Volker Heinemann, Sebastian Stintzing, Tanja Trarbach, Dominik Paul Modest
Publikováno v:
Journal of Clinical Oncology. 41:51-51
51 Background: The PANAMA study demonstrated superior progression-free survival (PFS) with the addition of panitumumab (Pmab) to fluorouracil and folinic acid (FU/FA) as maintenance therapy following first-line induction therapy with FOLFOX/Pmab in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f0f2b8cbb3324cdc683575fb7a8af56
https://doi.org/10.1200/jco.2023.41.4_suppl.51
https://doi.org/10.1200/jco.2023.41.4_suppl.51
Publikováno v:
Advances in Therapy
Introduction Febrile neutropenia (FN) is a serious and frequent complication of cytotoxic chemotherapy. Biosimilar filgrastim (Nivestim™, Hospira Inc, A Pfizer Company, Lake Forest, IL, USA) is a granulocyte-colony stimulating factor licensed for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccf9bbb4ad10e02843ef7514594c95a
http://europepmc.org/articles/PMC5083766
http://europepmc.org/articles/PMC5083766
Autor:
Doreen Heckmann, W. Jens Zeller, Stephanie Laufs, Heike Allgayer, Patrick Maier, Frederik Wenz, Stefan Fruehauf
Publikováno v:
Translational Oncology. 6(2):124-132
BACKGROUND: Signaling through stromal cell-derived factor-1α (SDF-1α), strongly secreted by bone marrow stromal cells and the CXC chemokine receptor 4 (CXCR4) exposed on tumor cells has pivotal roles in proliferation, metastasis, and tumor cell “
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8f30a73b6b429431056ac387ea1188