Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Stefan, Floess"'
Autor:
Melanie Bühler, Dandan Li, Lin Li, Sandra Runft, Inken Waltl, Andreas Pavlou, Ulrich Kalinke, Malgorzata Ciurkiewicz, Jochen Huehn, Stefan Floess, Andreas Beineke, Wolfgang Baumgärtner, Ingo Gerhauser
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Theiler’s murine encephalomyelitis virus (TMEV) is a single-stranded RNA virus that causes encephalitis followed by chronic demyelination in SJL mice and spontaneous seizures in C57BL/6 mice. Since earlier studies indicated a cr
Externí odkaz:
https://doaj.org/article/e30bc8fc773a48b2ba2840f704b52b59
Autor:
Joern Pezoldt, Carolin Wiechers, Mangge Zou, Maria Litovchenko, Marjan Biocanin, Michael Beckstette, Katarzyna Sitnik, Martina Palatella, Guido van Mierlo, Wanze Chen, Vincent Gardeux, Stefan Floess, Maria Ebel, Julie Russeil, Panagiota Arampatzi, Ehsan Vafardanejad, Antoine-Emmanuel Saliba, Bart Deplancke, Jochen Huehn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Lymph nodes in various locations of the body differ in their cell composition and gene expression signatures. Here authors show that the rapid postnatal expansion of lymph nodes is governed by CD34 + stromal cells and fibroblastic reticular stromal c
Externí odkaz:
https://doaj.org/article/a6cebd9a2df24f8cacb6093aef1fff24
Autor:
Peggy Riese, Stephanie Trittel, Manas K. Akmatov, Marcus May, Jana Prokein, Thomas Illig, Christoph Schindler, Birgit Sawitzki, Yassin Elfaki, Stefan Floess, Jochen Huehn, Adrian J. Błażejewski, Till Strowig, Esteban A. Hernandez-Vargas, Robert Geffers, Bowen Zhang, Yang Li, Frank Pessler, Carlos A. Guzmán
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Seasonal influenza vaccination is an important strategy to prevent serious disease in the elderly, but individual responsiveness to vaccination widely vary. Here authors establish, with an array of state-of-the art methods, the major immunological pa
Externí odkaz:
https://doaj.org/article/9417193549c440fd81f568927dc6de4e
Autor:
Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C. Barry, Jochen Huehn, Lorenzo Bonaguro, Thomas Ulas, Marc Beyer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD4+ T cells play a central role in the adaptive immune response through their capacity to activate, support and control other immune cells. Although these cells have become the focus of intense research, a comprehensive understanding of the underlyi
Externí odkaz:
https://doaj.org/article/08e3960cd2734ae4aaeb37de7e1fb8d2
Autor:
Shuting Li, Chia-Wen Lu, Elia C. Diem, Wang Li, Melanie Guderian, Marc Lindenberg, Friederike Kruse, Manuela Buettner, Stefan Floess, Markus R. Winny, Robert Geffers, Hans-Hermann Richnow, Wolf-Rainer Abraham, Guntram A. Grassl, Matthias Lochner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here the authors report that inhibition of de novo fatty acid synthesis by deleting the enzyme Acetyl-CoA-Carboxylase 1 in the intestinal epithelium results in the loss of crypt structures and a specific decline in Lgr5+ intestinal epithelial stem ce
Externí odkaz:
https://doaj.org/article/7000115314134be5b8f02dfada5b3128
Autor:
Kathrin L. Braband, Tamara Kaufmann, Stefan Floess, Mangge Zou, Jochen Huehn, Michael Delacher
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T cells in non-lymphoid tissues are not only critical for maintaining self-tolerance, but are also important for promoting organ homeostasis and tissue repair. It is proposed that the generation of tissue Treg cells is a stepwise, multi-si
Externí odkaz:
https://doaj.org/article/914b0a3aab7543979c780dd8986835e0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The first wave of Foxp3+ regulatory T cells (Tregs) generated in neonates is critical for the life-long prevention of autoimmunity. Although it is widely accepted that neonates are highly susceptible to infections, the impact of neonatal infections o
Externí odkaz:
https://doaj.org/article/b8920fad69424ef2b18a7fbada3e88e4
Autor:
Agnes Bonifacius, Oliver Goldmann, Stefan Floess, Silva Holtfreter, Philippe A. Robert, Maria Nordengrün, Friederike Kruse, Matthias Lochner, Christine S. Falk, Ingo Schmitz, Barbara M. Bröker, Eva Medina, Jochen Huehn
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Staphylococcus aureus can cause life-threatening diseases, and hospital- as well as community-associated antibiotic-resistant strains are an emerging global public health problem. Therefore, prophylactic vaccines or immune-based therapies are conside
Externí odkaz:
https://doaj.org/article/ecb0f7bd7d2c4295a7d1dae990335be1
Autor:
Joern Pezoldt, Maria Pasztoi, Mangge Zou, Carolin Wiechers, Michael Beckstette, Guilhem R. Thierry, Ehsan Vafadarnejad, Stefan Floess, Panagiota Arampatzi, Manuela Buettner, Janina Schweer, Diana Fleissner, Marius Vital, Dietmar H. Pieper, Marijana Basic, Petra Dersch, Till Strowig, Mathias Hornef, André Bleich, Ulrike Bode, Oliver Pabst, Marc Bajénoff, Antoine-Emmanuel Saliba, Jochen Huehn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Induction of tolerance in the gut relies on immunomodulatory functions of mesenteric lymph nodes (mLN). Here the authors show that mLN stromal cells receive early microbiota imprinting in the neonatal phase to exhibit long-term, location-specific tra
Externí odkaz:
https://doaj.org/article/3d292c2802f1404fac2cc90eb9e52fbb
Autor:
Liisa Andersen, Alexandra Franziska Gülich, Marlis Alteneder, Teresa Preglej, Maria Jonah Orola, Narendra Dhele, Valentina Stolz, Alexandra Schebesta, Patricia Hamminger, Anastasiya Hladik, Stefan Floess, Thomas Krausgruber, Thomas Faux, Syed Bilal Ahmad Andrabi, Jochen Huehn, Sylvia Knapp, Tim Sparwasser, Christoph Bock, Asta Laiho, Laura L. Elo, Omid Rasool, Riitta Lahesmaa, Shinya Sakaguchi, Wilfried Ellmeier
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4447-4459.e6 (2019)
Summary: Forkhead box protein P3+ (FOXP3+) regulatory T cells (Treg cells) play a key role in maintaining tolerance and immune homeostasis. Here, we report that a T cell-specific deletion of the transcription factor MAZR (also known as PATZ1) leads t
Externí odkaz:
https://doaj.org/article/974129bdad3742e980b60d2cd2ed4c8c