Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Stefan, Fest"'
Autor:
Roald Pfannes, Arkadiusz Pierzchalski, Ambra Maddalon, Alexandra Simion, Christos C. Zouboulis, Gerhard Behre, Ana Claudia Zenclussen, Sabine Westphal, Stefan Fest, Gunda Herberth
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTo evaluate the benefits of SARS-CoV-2 vaccination in cancer patients it is relevant to understand the adaptive immune response elicited after vaccination. Patients affected by hematologic malignancies are frequently immune-compromised and
Externí odkaz:
https://doaj.org/article/1b3fb997a1fe401781cf7f3a93d5c7b3
Autor:
Violeta Stojanovska, Susanne Arnold, Mario Bauer, Hermann Voss, Stefan Fest, Ana Claudia Zenclussen
Publikováno v:
Cells, Vol 11, Iss 18, p 2884 (2022)
It was postulated that 3D cell culture models more accurately reflect the complex tissue physiology and morphology in comparison to 2D cell monolayers. Currently, there is a shortage of well-characterized and easily maintainable high-throughput exper
Externí odkaz:
https://doaj.org/article/c7b68a93e8704ed39af86e2dcd08d07f
Autor:
Laura Liebscher, Stefanie Langwisch, Holger Christiansen, Ana Claudia Zenclussen, Christine Weißenborn, Robert Preissner, Björn-Oliver Gohlke, Gabriel A. Rabinovich, Nina M. Christiansen, Stefan Fest
Publikováno v:
Cancer Letters. 509:105-114
We recently identified Galectin-1 (Gal-1), a β-galactoside-binding lectin, as a novel immune regulator in neuroblastoma (NB). Here, we characterized the tolerogenic function of Gal-1 within the CD8+ T cell compartment and further evaluated its relev
Autor:
Anne Schumacher, Paul Ojiambo Wafula, Ana Teles, Tarek El-Mousleh, Nadja Linzke, Maria Laura Zenclussen, Stefanie Langwisch, Kristina Heinze, Ivonne Wollenberg, Pablo Ariel Casalis, Hans-Dieter Volk, Stefan Fest, Ana Claudia Zenclussen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42301 (2012)
Regulatory T cells (Treg) play an important role in fetal protection. They expand during normal pregnancy and protect fetal antigens from maternal effector cells. Their effect is associated with the up-regulation of tolerance-associated molecules at
Externí odkaz:
https://doaj.org/article/6b94097b58b1475ca9ff63cbf4f9adb2
Autor:
Christiane Fritzsch, Birgit Brett, Anke Redlich, Anke Rissmann, Claudia Spillner, Serban-Dan Costa, Jacqueline Färber, Hannah Rütten, Ilona Päge, Anke Lux, Birgit Doßow, Stefan Fest
Publikováno v:
Archives of Gynecology and Obstetrics. 296:231-240
This is the first study to determine the cytomegalovirus (CMV) seronegativity rate for women of childbearing age in Saxony-Anhalt and to determine the prevalence of clinically relevant congenital CMV (cCMV) infection in Central Germany, because there
Autor:
Ana Claudia Zenclussen, Mandy Busse, Serban-Dan Costa, Anke Redlich, Henning Rathert, Roland Hartig, Stefan Fest
Publikováno v:
Journal of Reproductive Immunology. 145:103319
Preterm birth (PTB) is one of the most frequent pregnancy complications. It affects millions of babies each year worldwide and is associated with increased morbidity and mortality. PTB-associated alterations in the maternal immune response may have a
Autor:
Holger N. Lode, Ana Claudia Zenclussen, Jana Kilz, Elisa Berger, Nina M. Christiansen, Stefan Fest, Sven Starke, Christoph Engel, Holger Christiansen, Maria Laura Zenclussen, Rocío Soldati
Publikováno v:
International Journal of Cancer. 138:2030-2042
Heme oxygenase (HO)-1 catalyzes the degradation of cytotoxic heme into biliverdin and blocks antitumor immune responses, thus protecting cancer against host defense. Whether this scenario also applies to neuroblastoma (NB), the most common extracrani
Autor:
Stefan Fest
Publikováno v:
Cancer Research. 79:4559-4559
Question We recently introduced the carbohydrate-binding protein Galectin-1 (Gal-1) as a novel tolerogeneic molecule in neuroblastoma (NB). NB-secreted Gal-1 suppressed the maturation of dendritic cells (DC) and inhibited T cell function. Here, we fo
Autor:
Sophie von Lenthe, Christine Weißenborn, Ana Claudia Zenclussen, Stefan Fest, Leonid Metelitsa
Publikováno v:
Cancer Research. 79:4570-4570
Purpose of the study Neuroblastoma (NB) is the most common solid extracranial tumor in childhood. Regulatory T cells (Treg) are known to have immune suppressive capacity and to be involved in tolerance establishment. As they support tumor growth and
Publikováno v:
Open Medicine, Vol 8, Iss 6, Pp 697-706 (2013)
Background. Cancer in childhood is rare, but nevertheless one of the most frequent causes of disease related death. Initial symptoms are often unspecific, frequently leading to a delay of cancer diagnosis. As a timely diagnosis can be crucial for the