Zobrazeno 1 - 10
of 4 443
pro vyhledávání: '"Stefan, F."'
Autor:
Craft, Clayton L., Barton, Nicholas J., Klug, Andrew C., Scalzi, Kenneth, Wildemann, Ian, Asagodu, Pramod, Broz, Joseph D., Porto, Nikola L., Macalik, Michael, Rizzo, Anthony, Percevault, Garrett, Tison, Christopher C., Smith, A. Matthew, Fanto, Michael L., Schneeloch, James, Sheridan, Erin, Heberle, Dylan, Brownell, Andrew, Sundaram, Vijay S. S., Deenadayalan, Venkatesh, van Niekerk, Matthew, Manfreda-Schulz, Evan, Howland, Gregory A., Preble, Stefan F., Coleman, Daniel, Leake, Gerald, Antohe, Alin, Vo, Tuan, Fahrenkopf, Nicholas M., Stievater, Todd H., Brickman-Soderberg, Kathy-Anne, Smith, Zachary S., Hucul, David
Reliable control of quantum information in matter-based qubits requires precisely applied external fields, and unaccounted for spatial cross-talk of these fields between adjacent qubits leads to loss of fidelity. We report a CMOS foundry-produced, mi
Externí odkaz:
http://arxiv.org/abs/2406.17607
Recent work has demonstrated that the latent spaces of large language models (LLMs) contain directions predictive of the truth of sentences. Multiple methods recover such directions and build probes that are described as getting at a model's "knowled
Externí odkaz:
http://arxiv.org/abs/2404.18865
Natural language reasoning plays an increasingly important role in improving language models' ability to solve complex language understanding tasks. An interesting use case for reasoning is the resolution of context-dependent ambiguity. But no resour
Externí odkaz:
http://arxiv.org/abs/2310.14657
Given the dynamic nature of toxic language use, automated methods for detecting toxic spans are likely to encounter distributional shift. To explore this phenomenon, we evaluate three approaches for detecting toxic spans under cross-domain conditions
Externí odkaz:
http://arxiv.org/abs/2306.09642
Autor:
Isis Wolf, Jonas Storz, Susanne Schultze-Seemann, Philipp R. Esser, Stefan F. Martin, Susan Lauw, Peer Fischer, Marie Peschers, Wolfgang Melchinger, Robert Zeiser, Oliver Gorka, Olaf Groß, Christian Gratzke, Reinhard Brückner, Philipp Wolf
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 537-552 (2024)
Photoimmunotherapy (PIT) combines the specificity of antibodies with the cytotoxicity of light activatable photosensitizers (PS) and is a promising new cancer therapy. We designed and synthesized, in a highly convergent manner, the silicon phthalocya
Externí odkaz:
https://doaj.org/article/ee35b5cb8cf245868148c021c5ec968b
Autor:
Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R. Vetter, Patricia Stege, Steven G. Burston, Anto Filipovic, Yasser B. Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres-Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A. Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F. Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Loss-of-function mutations in the homotrimeric serine protease HTRA1 cause cerebral vasculopathy. Here, we establish independent approaches to achieve the functional correction of trimer assembly defects. Focusing on the prototypical R274Q m
Externí odkaz:
https://doaj.org/article/ecefd6f18eff4edf90c7e557870791d5
Autor:
Martin Bernert, Monique J. Bignoux, Chandni Madhav, Sichumiso Gqeba, Tyrone C. Otgaar, Gavin Morris, Stefan F. T. Weiss, Eloise Ferreira
Publikováno v:
FEBS Open Bio, Vol 14, Iss 7, Pp 1072-1086 (2024)
Telomerase activity is directly affected by the laminin receptor precursor (LRP) protein, a highly conserved nonintegrin transmembrane receptor, which has been shown to have therapeutic effects in ageing, and age‐related diseases. Recently, it has
Externí odkaz:
https://doaj.org/article/c5bbe0960aa9461e83bd2e9280259f19