Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Stefan, Barth"'
Autor:
Mei Lu, Haonan Xing, Wanxuan Shao, Pengfei Wu, Yuchuan Fan, Huining He, Stefan Barth, Aiping Zheng, Xing-Jie Liang, Yuanyu Huang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 9, Pp 3945-3955 (2023)
Immunotherapy has revolutionized the landscape of cancer treatment. However, single immunotherapy only works well in a small subset of patients. Combined immunotherapy with antitumor synergism holds considerable potential to boost the therapeutic out
Externí odkaz:
https://doaj.org/article/f3a9f81567984c40a01202e52b271d53
Autor:
Musalula Sinkala, Krupa Naran, Dharanidharan Ramamurthy, Neelakshi Mungra, Kevin Dzobo, Darren Martin, Stefan Barth
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296511 (2024)
Breast cancer responds variably to anticancer therapies, often leading to significant off-target effects. This study proposes that the variability in tumour responses and drug-induced adverse events is linked to the transcriptional profiles of cell s
Externí odkaz:
https://doaj.org/article/117e269f77ff4e0d912e5e1b88de12cc
Autor:
Ridhwaanah Jacobs, Makafui Dennis Dogbey, Njabulo Mnyandu, Keila Neves, Stefan Barth, Patrick Arbuthnot, Mohube Betty Maepa
Publikováno v:
Microorganisms, Vol 11, Iss 12, p 2985 (2023)
Hepatitis B virus (HBV) has afflicted humankind for decades and there is still no treatment that can clear the infection. The development of recombinant adeno-associated virus (rAAV)-based gene therapy for HBV infection has become important in recent
Externí odkaz:
https://doaj.org/article/d0c6413a36ca492399e5c5715e39fed7
Autor:
Weiran Cao, Rui Li, Xing Pei, Meihong Chai, Lu Sun, Yuanyu Huang, Jiancheng Wang, Stefan Barth, Fei Yu, Huining He
Publikováno v:
Medicine in Drug Discovery, Vol 15, Iss , Pp 100128- (2022)
Antibody–drug conjugates (ADC) utilizing the targeting properties of antibodies and therapeutic effects of drugs have emerged a rapid development in recent years. However, the relatively low drug loading capacity of ADC systems commonly results in
Externí odkaz:
https://doaj.org/article/d6da9aa89b1b4a4bbbb6bd7088a00d52
Autor:
Melanie Seidel-Greven, Otchere Addai-Mensah, Holger Spiegel, Gwladys Nina Chiegoua Dipah, Stefan Schmitz, Gudrun Breuer, Margaret Frempong, Andreas Reimann, Torsten Klockenbring, Rainer Fischer, Stefan Barth, Rolf Fendel
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract Background Plasmodium falciparum, the parasite causing malaria, affects populations in many endemic countries threatening mainly individuals with low malaria immunity, especially children. Despite the approval of the first malaria vaccine Mo
Externí odkaz:
https://doaj.org/article/4ef67ba7a0174ef2bfb421a7ccc904ff
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2158 (2022)
Melanoma is highly aggressive and is known to be efficient at resisting drug-induced apoptotic signals. Resection is currently the gold standard for melanoma management, but it only offers local control of the early stage of the disease. Metastatic m
Externí odkaz:
https://doaj.org/article/d26ecdbcb05049fd9bdaf5dd2db2e84f
Autor:
Allan M. Huysamen, Olaolu E. Fadeyi, Grace Mayuni, Dennis M. Dogbey, Neelakshi Mungra, Fleury A. N. Biteghe, Natasha Hardcastle, Dharanidharan Ramamurthy, Olusiji A. Akinrinmade, Krupa Naran, Susan Cooper, Dirk Lang, Wolfgang Richter, Roger Hunter, Stefan Barth
Publikováno v:
ACS Omega. 8:4026-4037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::babf604561c325a4d7d0fba1b25f3431
https://doi.org/10.1021/acsomega.2c06844
https://doi.org/10.1021/acsomega.2c06844
Publikováno v:
Biomacromolecules. 24:517-530
The conjugation of proteins with synthetic molecules can be conducted in many different ways. In this Perspective, we focus on tag-based techniques and specifically on the SNAP-tag technology. The SNAP-tag technology makes use of a fusion protein bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9134ec1fee79af98e5c1d8d38f30024
https://doi.org/10.1021/acs.biomac.2c01238
https://doi.org/10.1021/acs.biomac.2c01238
Autor:
Lorenz Thurner, Sylvia Hartmann, Moritz Bewarder, Natalie Fadle, Evi Regitz, Claudia Schormann, Natalia Quiroga, Maria Kemele, Wolfram Klapper, Andreas Rosenwald, Lorenz Trümper, Rainer Maria Bohle, Anna Nimmesgern, Christina Körbel, Matthias W. Lascke, Michael D. Menger, Stefan Barth, Boris Kubuschok, Anja Mottok, Dominic Kaddu-Mulindwa, Martin-Leo Hansmann, Viola Pöschel, Gerhard Held, Niels Murawski, Stephan Stilgenbauer, Frank Neumann, Klaus-Dieter Preuss, Michael Pfreundschuh
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
It has been suggested that B-cell receptor (BCRs) stimulation by specific antigens plays a pathogenic role in diffuse large B-cell lymphoma (DLBCL). Here, it was the aim to screen for specific reactivities of DLBCL-BCRs in the spectrum of autoantigen
Externí odkaz:
https://doaj.org/article/931663a810f741b99241bc4117b18d0c
Autor:
Mira Woitok, Elena Grieger, Olusiji A Akinrinmade, Susanne Bethke, Anh Tuan Pham, Christoph Stein, Rolf Fendel, Rainer Fischer, Stefan Barth, Judith Niesen
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243286 (2020)
In vitro and ex vivo development of novel therapeutic agents requires reliable and accurate analyses of the cell conditions they were preclinical tested for, such as apoptosis. The detection of apoptotic cells by annexin V (AV) coupled to fluorophore
Externí odkaz:
https://doaj.org/article/c05b4978132b4524b68c1177dd13fb04