Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Stefaan W, Verbruggen"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Cell-based therapies represent the current frontier of biomedical innovations, with the technologies required underpinning treatments as broad as CAR-T cell therapies, stem cell treatments, genetic therapies and mRNA manufacture. A key bottleneck in
Externí odkaz:
https://doaj.org/article/80e138cf45c0402d85e2a7b20dea8bbe
Autor:
Stefaan W. Verbruggen
Publikováno v:
Journal of Bone Oncology, Vol 44, Iss , Pp 100526- (2024)
Metastatic bone disease is a complex condition resulting from the migration and colonization of cancer cells from their primary site to the bone microenvironment, where they typically develop a metastatic niche. Osteocytes, the most abundant cells in
Externí odkaz:
https://doaj.org/article/2b5df1ffecff46649e5bffde3376bd24
Autor:
Stefaan W. Verbruggen, Joanne Nolan, Michael P. Duffy, Oliver M.T. Pearce, Christopher R. Jacobs, Martin M. Knight
Publikováno v:
Advanced Science, Vol 11, Iss 2, Pp n/a-n/a (2024)
Abstract Bone metastases are a common cause of suffering in breast and prostate cancer patients, however, the interaction between bone cells and cancer cells is poorly understood. Using a series of co‐culture, conditioned media, human cancer sphero
Externí odkaz:
https://doaj.org/article/76aa04d7a7fa4f45a303ab43a8ff8637
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0171588 (2017)
The fetal membrane surrounds the fetus during pregnancy and is a thin tissue composed of two layers, the chorion and the amnion. While rupture of this membrane normally occurs at term, preterm rupture can result in increased risk of fetal mortality a
Externí odkaz:
https://doaj.org/article/96d71f2c7a354fbe840ace64d08f0a20
Autor:
Joanne Nolan, Oliver M. T. Pearce, Hazel R. C. Screen, Martin M. Knight, Stefaan W. Verbruggen
Publikováno v:
Cancers. 15:635
Organ-on-chip systems are capable of replicating complex tissue structures and physiological phenomena. The fine control of biochemical and biomechanical cues within these microphysiological systems provides opportunities for cancer researchers to bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf730d0176c9688bc1434fda548bee0
https://doi.org/10.3390/cancers15030635
https://doi.org/10.3390/cancers15030635
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 25
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 25
Significance Bone fragility increases with age as the result of the concurrent decline of bone mass, quality, and mechanosensitivity. While the coordinated decline of these behaviors remains unexplained, the role of osteocytes in each of these proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cd7537561b655703a51a3e86b64d25
http://europepmc.org/articles/PMC8237574
http://europepmc.org/articles/PMC8237574
Autor:
Stefaan W. Verbruggen, Michael P. Duffy, Christopher R. Jacobs, Joanne Nolan, Clare L. Thompson, Sophia Lunetto, Oliver M. T. Pearce, Martin M. Knight
Publikováno v:
Cancers
Volume 13
Issue 12
Cancers, Vol 13, Iss 2906, p 2906 (2021)
Volume 13
Issue 12
Cancers, Vol 13, Iss 2906, p 2906 (2021)
Simple Summary Metastatic lesions in bone tissue are a common complication in breast and prostate cancer patients, accounting for the larger part of pain and suffering in late-stage cancer. The metastatic cancer cells that form these lesions must tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5107a5d3931cb9344a81e55a9e75ff
https://doi.org/10.3390/cancers13122906
https://doi.org/10.3390/cancers13122906
Autor:
Stefaan W. Verbruggen, Niamh C. Nowlan
Publikováno v:
The Anatomical Record. 300:643-652
The human pelvis has evolved over time into a remarkable structure, optimised into an intricate architecture that transfers the entire load of the upper body into the lower limbs, while also facilitating bipedal movement. The pelvic girdle is compose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b153b2e870b09a8631ecb0a5e4702d
https://doi.org/10.1002/ar.23541
https://doi.org/10.1002/ar.23541
Autor:
Stefaan W, Verbruggen, Bernhard, Kainz, Susan C, Shelmerdine, Owen J, Arthurs, Joseph V, Hajnal, Mary A, Rutherford, Andrew T M, Phillips, Niamh C, Nowlan
Publikováno v:
Journal of biomechanics. 78
Fetal kicking and movements generate biomechanical stimulation in the fetal skeleton, which is important for prenatal musculoskeletal development, particularly joint shape. Developmental dysplasia of the hip (DDH) is the most common joint shape abnor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b049a7649b10bcfa1e5cbb1c6fba448
https://pubmed.ncbi.nlm.nih.gov/30037582
https://pubmed.ncbi.nlm.nih.gov/30037582
Bone demonstrates a remarkable ability to renew itself, adapt its architecture, and repair fractures to maintain strength throughout life. Mechanobiology, the study of how external mechanical loading on the bone is transferred to bone cells and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410eb1d19e000fc1dde7bc50fa3f87b1
https://doi.org/10.1016/b978-0-12-812952-4.00006-4
https://doi.org/10.1016/b978-0-12-812952-4.00006-4
