Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stefaan De Smedt"'
Autor:
Juan C. Fraire, Elnaz Shaabani, Maryam Sharifiaghdam, Matthias Rombaut, Charlotte Hinnekens, Dawei Hua, Jana Ramon, Laurens Raes, Eduardo Bolea-Fernandez, Toon Brans, Frank Vanhaecke, Peter Borghgraef, Chaobo Huang, Félix Sauvage, Tamara Vanhaecke, Joery De Kock, Ranhua Xiong, Stefaan De Smedt, Kevin Braeckmans
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Ballistic delivery with micro/nano-particles has been successfully used to transfect plant cells, however, has failed in mammalian cells due to toxic effects. Here, the authors report on a self-assembled nano-ballistic delivery system for the deliver
Externí odkaz:
https://doaj.org/article/77d1d8da1f724b5b9fd372d74134f2d8
Autor:
Laurens Raes, Stephan Stremersch, Juan C. Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, Xavier Saelens, Bart Vandekerckhove, Stefaan De Smedt, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Nano-Micro Letters, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Efficient and safe cell engineering by transfection of nucleic acids remains one of the long-standing hurdles for fundamental biomedical research and many new therapeutic applications, such as CAR T cell-based therapies. mRNA has recently ga
Externí odkaz:
https://doaj.org/article/543a96ad06524b4f9271212ffb59401e
Autor:
Maryam Sharifiaghdam, Elnaz Shaabani, Zeynab Sharifiaghdam, Herlinde De Keersmaecker, Riet De Rycke, Stefaan De Smedt, Reza Faridi-Majidi, Kevin Braeckmans, Juan C. Fraire
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Nanotechnology has made an important contribution to oncology in recent years, especially for drug delivery. While many different nano-delivery systems have been suggested for cancer therapy, selenium nanoparticles (SeNPs) are particularly promising
Externí odkaz:
https://doaj.org/article/42bb1b9f3e2d48a1badbe7a54956b04e
Autor:
Juan C. Fraire, Elnaz Shaabani, Maryam Sharifiaghdam, Matthias Rombaut, Charlotte Hinnekens, Dawei Hua, Jana Ramon, Laurens Raes, Eduardo Bolea-Fernandez, Toon Brans, Frank Vanhaecke, Peter Borghgraef, Chaobo Huang, Félix Sauvage, Tamara Vanhaecke, Joery De Kock, Ranhua Xiong, Stefaan De Smedt, Kevin Braeckmans
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/97139893485c48219873888d3906c3b8
Autor:
Sara Pereira, Rita Sobral Santos, Luís Moreira, Nuno Guimarães, Mariana Gomes, Heyang Zhang, Katrien Remaut, Kevin Braeckmans, Stefaan De Smedt, Nuno Filipe Azevedo
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 989 (2021)
Bacterial resistance to antibiotics threatens the ability to treat life-threatening bloodstream infections. Oligonucleotides (ONs) composed of nucleic acid mimics (NAMs) able to inhibit essential genes can become an alternative to traditional antibio
Externí odkaz:
https://doaj.org/article/13ea93219bcb4452bedcd9029e6a5bb8
Autor:
Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan C. Fraire, Toon Brans, Ranhua Xiong, Stefaan De Smedt, Linos Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Crystals, Vol 9, Iss 8, p 411 (2019)
The modification of CD4+ T cells with exogenous nucleic acids or proteins is a critical step in several research and therapeutic applications, such as HIV studies and cancer immunotherapies. However, efficient cell transfections are not always easily
Externí odkaz:
https://doaj.org/article/5f79c192ee3943908590f8ae3310d25b
Publikováno v:
EXPERT OPINION ON DRUG DELIVERY
Introduction Retinal disease affects millions of people worldwide, generating a massive social and economic burden. Current clinical trials for retinal diseases are dominated by gene augmentation therapies delivered with recombinant viruses as key pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31c0c593934a350d472871510d65b97
https://doi.org/10.1080/17425247.2023.2167979
https://doi.org/10.1080/17425247.2023.2167979
Autor:
Inès De Hoon, Alexandre Barras, Tomasz Swebocki, Bernd Vanmeerhaeghe, Bram Bogaert, Cristina Muntean, Amar Abderrahmani, Rabah Boukherroub, Stefaan De Smedt, Félix Sauvage, Sabine Szunerits
Publikováno v:
ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces, 2023, 15 (3), pp.3760-3771. ⟨10.1021/acsami.2c18598⟩
ACS Applied Materials & Interfaces, 2023, 15 (3), pp.3760-3771. ⟨10.1021/acsami.2c18598⟩
International audience; Reaching the corneal endothelium through the topical administration of therapeutic drugs remains a challenge in ophthalmology. Besides, endothelial cells are not able to regenerate, and diseases at this site can lead to cornea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdde499157e1e6c841ae3a3f88bef4f
https://doi.org/10.1021/acsami.2c18598
https://doi.org/10.1021/acsami.2c18598
Autor:
Sangram Keshari Samal, Stefaan Soenen, Dario Puppi, Karolien De Wael, Sanghamitra Pati, Stefaan De Smedt, Kevin Braeckmans, Peter Dubruel
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11867
International journal of molecular sciences
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International journal of molecular sciences
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
The bio-nanohybrid gelatin protein/cadmium sulfide (Gel/CdS) quantum dots (QDs) have been designed via a facile one-pot strategy. The amino acids group of gelatin chelate Cd2+ and grow CdS QDs without any agglomeration. The 1H NMR spectra indicate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192ad94df74f18d4118642c3b3badddc
Autor:
Rupert L. Mayer, Rein Verbeke, Caroline Asselman, Ilke Aernout, Adillah Gul, Denzel Eggermont, Katie Boucher, Fabien Thery, Teresa M. Maia, Hans Demol, Ralf Gabriels, Lennart Martens, Christophe Bécavin, Stefaan De Smedt, Bart Vandekerckhove, Ine Lentacker, Francis Impens
Listeria monocytogenesis a foodborne intracellular bacterial pathogen leading to human listeriosis. Despite a high mortality rate and increasing antibiotic resistance no clinically approved vaccine againstListeriais available. AttenuatedListeriastrai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e503745a82a08f8ffc5d0d184f1e4979
https://doi.org/10.1101/2022.08.19.504521
https://doi.org/10.1101/2022.08.19.504521
