Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Stef De Lombaerde"'
Autor:
Taco Metelerkamp Cappenberg, Stijn De Schepper, Christel Vangestel, Stef De Lombaerde, Leonie wyffels, Tim Van den Wyngaert, Jeffrey Mattis, Brian Gray, Koon Pak, Sigrid Stroobants, Filipe Elvas
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Background Imaging of cell death can provide an early indication of treatment response in cancer. [99mTc]Tc-Duramycin is a small-peptide SPECT tracer that recognizes both apoptotic and necrotic cells by binding to phosphatidylethanolamine pr
Externí odkaz:
https://doaj.org/article/5e5aa09daddc4fbdbefd750b6971e189
Autor:
Dorien Glorie, Jeroen Verhaeghe, Alan Miranda, Stef De Lombaerde, Sigrid Stroobants, Steven Staelens
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Background Currently, the evidence on synaptic abnormalities in neuropsychiatric disorders—including obsessive–compulsive disorder (OCD)—is emerging. The newly established positron emission tomography (PET) ligand ((R)-1-((3-((11)C-met
Externí odkaz:
https://doaj.org/article/e74c766476b44ad69df8336b5e8e269e
Autor:
Euy Sung Moon, Filipe Elvas, Gwendolyn Vliegen, Stef De Lombaerde, Christel Vangestel, Sven De Bruycker, An Bracke, Elisabeth Eppard, Lukas Greifenstein, Benedikt Klasen, Vasko Kramer, Steven Staelens, Ingrid De Meester, Pieter Van der Veken, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-20 (2020)
Abstract Background Fibroblast activation protein (FAP) is a proline selective serine protease that is overexpressed in tumor stroma and in lesions of many other diseases that are characterized by tissue remodeling. In 2014, a most potent FAP-inhibit
Externí odkaz:
https://doaj.org/article/6eef6de76ec3424eabc82ef799f24e24
Autor:
Sigrid Stroobants, Dorien Glorie, Steven Staelens, Alan Miranda, Stef De Lombaerde, Jeroen Verhaeghe
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7:607-615
This study provides a first direct comparison between positron emission tomography (PET) radioligands targeting the allosteric site of the metabotropic glutamate receptor 5 (mGluR5): [11C]ABP688 and [18F]FPEB. A blocking paradigm was set up to substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::298fb7620dd559e6e7c6aea8b26f1bfa
https://doi.org/10.1016/j.bpsc.2021.11.010
https://doi.org/10.1016/j.bpsc.2021.11.010
Autor:
Daniele Bertoglio, Franziska Zajicek, Stef De Lombaerde, Alan Miranda, Sigrid Stroobants, Yuchuan Wang, Celia Dominguez, Ignacio Munoz-Sanjuan, Jonathan Bard, Longbin Liu, Jeroen Verhaeghe, Steven Staelens
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:1867-1878
Alterations in synaptic vesicle glycoprotein 2 A (SV2A) have been associated with several neuropsychiatric and neurodegenerative disorders. Therefore, SV2A positron emission tomography (PET) imaging may provide a unique tool to investigate synaptic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2a2e5be38779b9b5fdecc6a6342a89
https://doi.org/10.1177/0271678x221101648
https://doi.org/10.1177/0271678x221101648
Autor:
Daniele Bertoglio, Nicolas Halloin, Stef De Lombaerde, Aleksandar Jankovski, Jeroen Verhaeghe, Charles Nicaise, Steven Staelens
Publikováno v:
The Journal of nuclear medicine
J Nucl Med
Bertoglio, D, Halloin, N, De Lombaerde, S, Jankovski, A, Verhaeghe, J, Nicaise, C & Staelens, S 2022, ' SV2A PET imaging is a non-invasive marker for the detection of spinal damages in experimental models of spinal cord injury ', Journal of nuclear medicine, vol. 63, no. 8, pp. 1245-1251 . https://doi.org/10.2967/jnumed.121.263222
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 63, no.8, p. 1245-1251 (2022)
J Nucl Med
Bertoglio, D, Halloin, N, De Lombaerde, S, Jankovski, A, Verhaeghe, J, Nicaise, C & Staelens, S 2022, ' SV2A PET imaging is a non-invasive marker for the detection of spinal damages in experimental models of spinal cord injury ', Journal of nuclear medicine, vol. 63, no. 8, pp. 1245-1251 . https://doi.org/10.2967/jnumed.121.263222
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 63, no.8, p. 1245-1251 (2022)
Traumatic spinal cord injury (SCI) is a neurological condition characterized by long-term motor and sensory neurological deficits as a consequence of an external physical impact damaging the spinal cord. Anatomical magnetic resonance imaging (MRI) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54545a2d2510697a61422c9360b3b5a
https://doi.org/10.2967/jnumed.121.263222
https://doi.org/10.2967/jnumed.121.263222
Autor:
Stef De Lombaerde, Sara Neyt, Ken Kersemans, Jeroen Verhoeven, Lindsey Devisscher, Hans Van Vlierberghe, Christian Vanhove, Filip De Vos
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173529 (2017)
INTRODUCTION:Drug-induced cholestasis is a liver disorder that might be caused by interference of drugs with the hepatobiliary bile acid transporters. It is important to identify this interference early on in drug development. In this work, Positron
Externí odkaz:
https://doaj.org/article/29634cb3d36646a7922ca3988151a3c8
Autor:
Daniele Bertoglio, Jonathan Bard, Manuela Hessmann, Longbin Liu, Annette Gärtner, Stef De Lombaerde, Britta Huscher, Franziska Zajicek, Alan Miranda, Finn Peters, Frank Herrmann, Sabine Schaertl, Tamara Vasilkovska, Christopher J. Brown, Peter D. Johnson, Michael E. Prime, Matthew R. Mills, Annemie Van der Linden, Ladislav Mrzljak, Vinod Khetarpal, Yuchuan Wang, Deanna M. Marchionini, Mette Skinbjerg, Jeroen Verhaeghe, Celia Dominguez, Steven Staelens, Ignacio Munoz-Sanjuan
Publikováno v:
Science translational medicine
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin ( HTT ) gene that encodes the pathologic mutant HTT (mHTT) protein with an expanded polyglutamine (polyQ) tract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7662df57d6591cf33f3b646e6b47d98
https://repository.uantwerpen.be/docstore/d:irua:11094
https://repository.uantwerpen.be/docstore/d:irua:11094
Autor:
Dorien, Glorie, Jeroen, Verhaeghe, Alan, Miranda, Stef, De Lombaerde, Sigrid, Stroobants, Steven, Staelens
Publikováno v:
Biological psychiatry. Cognitive neuroscience and neuroimaging. 7(6)
This study provides a first direct comparison between positron emission tomography radioligands targeting the allosteric site of the metabotropic glutamate receptor 5 (mGluR5): [First, wild-type mice (n = 7) received four position emission tomography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc098a2752584524d4af9b14eac06fda
https://pubmed.ncbi.nlm.nih.gov/34856382
https://pubmed.ncbi.nlm.nih.gov/34856382
Autor:
Jan Goeman, Karel Deblaere, Stef De Lombaerde, Serge Van Calenbergh, Caroline Van den Broecke, Ken Kersemans, Johan Van der Eycken, Giorgio Hallaert, Christian Vanhove, Filip De Vos, Jeroen Verhoeven, Julie Bolcaen, Benedicte Descamps, Ingeborg Goethals, Fabian Hulpia
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-23 (2019)
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
The use of O-(2-[18F]fluoroethyl)-l-tyrosine ([18F]FET) as a positron emission tomography (PET) tracer for brain tumor imaging might have some limitations because of the relatively low affinity for the L-type amino acid transporter 1 (LAT1). To asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4142097e429ac36876a553be343fe495
http://link.springer.com/article/10.1038/s41598-019-40013-x
http://link.springer.com/article/10.1038/s41598-019-40013-x