Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Steen H, Hansen"'
Autor:
Steen H. Hansen
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/e5892ae2e1474d3d8316bc13ec5bd22c
Publikováno v:
Universe, Vol 10, Iss 5, p 193 (2024)
The accelerated expansion of the Universe is impressively well described by a cosmological constant. However, the observed value of the cosmological constant is much smaller than expected based on quantum field theories. Recent efforts to achieve con
Externí odkaz:
https://doaj.org/article/3baf148d8bd545cc81d9e1ea5d38ff48
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113486- (2023)
Summary: ARHGAP35, which encodes p190A RhoGAP (p190A), is a major cancer gene. p190A is a tumor suppressor that activates the Hippo pathway. p190A was originally cloned via direct binding to p120 RasGAP (RasGAP). Here, we determine that interaction o
Externí odkaz:
https://doaj.org/article/5984d7b2c84848beb239d1f7bdd79686
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Transporters of the inner mitochondrial membrane are essential to metabolism. We demonstrate that metabolism as represented by expression of genes encoding SLC25 transporters differentiates human cancers. Tumor to normal tissue expression ra
Externí odkaz:
https://doaj.org/article/d64b3a6f94644f5c98fc255c21a7b769
Autor:
Fabiano Tracanna, Steen H. Hansen
Publikováno v:
The Astrophysical Journal, Vol 957, Iss 1, p 2 (2023)
The majority of baryons, which account for 15% of the matter in the Universe, will end their lives as carbon and oxygen inside cold black dwarfs. Dark matter (DM) makes up the remaining 85% of the matter in the Universe; however, the fate of DM is un
Externí odkaz:
https://doaj.org/article/1bc6950fcae14f25a3e936d8bb00b766
Autor:
Kristoffer K. Hendel, Charlotte Bagger, Uffe H. Olesen, Christian Janfelt, Steen H. Hansen, Merete Haedersdal, Catharina M. Lerche
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 244-251 (2019)
Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of
Externí odkaz:
https://doaj.org/article/07e6d4529e5c4f52b5e2657aaca578eb
Autor:
Phi Luong, Matija Hedl, Jie Yan, Tao Zuo, Tian-Min Fu, Xiaomo Jiang, Jay R Thiagarajah, Steen H Hansen, Cammie F Lesser, Hao Wu, Clara Abraham, Wayne I Lencer
Publikováno v:
eLife, Vol 7 (2018)
Homeostasis at mucosal surfaces requires cross-talk between the environment and barrier epithelial cells. Disruption of barrier function typifies mucosal disease. Here we elucidate a bifunctional role in coordinating this cross-talk for the inflammat
Externí odkaz:
https://doaj.org/article/88d7b7c576ce48a69294af2d0e3bf0e0
Autor:
Eva Garde, Mads F. Bertelsen, Susanne Ditlevsen, Mads Peter Heide-Jørgensen, Nynne H. Nielsen, Anne K. Frie, Droplaug Olafsdottir, Ursula Siebert, Steen H. Hansen
Publikováno v:
NAMMCO Scientific Publications, Vol 10, Iss 0 (2018)
The aspartic acid racemization (AAR) technique has been applied for age estimation of humans and other mammals for more than four decades. In this study, eye lenses from 124 animals representing 25 mammalian species were collected and D/L ratios obta
Externí odkaz:
https://doaj.org/article/3541a803e91e4d3b92908fae25a2bfeb
Autor:
Nynne H Nielsen, Gísli A. Víkingsson, Steen H. Hansen, Susanne Ditlevsen, Mads Peter Heide-Jørgensen
Publikováno v:
NAMMCO Scientific Publications, Vol 10, Iss 0 (2017)
The ages of three species of cetaceans were estimated by counting the growth layer groups (GLG) and measuring the aspartic acid racemization rate (kAsp) by what is referred to as the Aspartic Acid Racemization (AAR) technique. Data on kAsp and the D/
Externí odkaz:
https://doaj.org/article/d6585a8c9a0c4336ac63165b64b22d3e
Publikováno v:
Oncogene
Ouyang, H, Luong, P, Frödin, M & Hansen, S H 2020, ' p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth ', Oncogene, vol. 39, no. 33, pp. 5570-5587 . https://doi.org/10.1038/s41388-020-1385-2
Ouyang, H, Luong, P, Frödin, M & Hansen, S H 2020, ' p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth ', Oncogene, vol. 39, no. 33, pp. 5570-5587 . https://doi.org/10.1038/s41388-020-1385-2
The ARHGAP35 gene encoding p190A RhoGAP (p190A) is significantly altered by both mutation and allelic deletion in human cancer, but the functional implications of such alterations are not known. Here, we demonstrate for the first time that p190A is a