Metabolic engineering of yeast for fermentative production of flavonoids

Autor: Jens Nielsen, Daniel Killerup Svenssen, Tomas Strucko, Irina Borodina, Mette Kristensen, Steen Gustav Stahlhut, Angelica Rodriguez, Jochen Förster

Publikováno v: Rodriguez Prado, E A, Strucko, T, Stahlhut, S G, Kristensen, M, Svenssen, D K, Förster, J, Nielsen, J & Borodina, I 2017, ' Metabolic engineering of yeast for fermentative production of flavonoids ', Bioresource Technology, vol. 245, no. Part B, pp. 1645-1654 . https://doi.org/10.1016/j.biortech.2017.06.043

Yeast Saccharomyces cerevisiae was engineered for de novo production of six different flavonoids (naringenin, liquiritigenin, kaempferol, resokaempferol, quercetin, and fisetin) directly from glucose, without supplementation of expensive intermediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7108f15c56518dfc9237735a53c4dce
https://doi.org/10.1016/j.biortech.2017.06.043

BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits

Autor: Shanshan Li, Mahdi Doostmohammadi, Markus Schmidt, Roberto Ferro, Camillo Meinhart, Morten H. H. Nørholm, Wei Wei, Marcel Ottens, Pilar Bañados, Ricardo Andrade, Mounir Benkoulouche, Derek Stewart, Martin Trick, Nuno Faria, Oscar P. Kuipers, Li-Jin Wang, Gonçalo Garcia, Marcelo Silva, Nicola Love, Ana Solopova, Wolfgang Kerbe, Björn Hamberger, David Méndez Sevillano, Laurent Bulteau, Armando M. Fernandes, Philippe Vain, Alice Julien-Laferriere, Liangsheng Wang, Harald Heider, Delphine Parrot, Cathie Martin, Joana Godinho-Pereira, Paula Gaspar, Barbara Avila, Michael Vogt, Dario Breitel, Jan Marienhagen, Ana Vila-Santa, Arnaud Mary, Artem Sorokin, Carolina Jardim, Jean-Etienne Bassard, Rex M. Brennan, Rafael S. Costa, Caroline Rousseau, Nicolai Kallscheuer, Louise V. T. Shepherd, Alexey Dudnik, A. Filipa Almeida, Vera Thole, Shang Su, Cheng-Yong Feng, André Veríssimo, Vincent Mazurek, Ana Rita Silva, Jochen Förster, Steen Gustav Stahlhut, Michael Naesby, András Hartmann, Alberto Marchetti-Spaccamela, Tatiana Shelenga, Céline Chanforan, Finn Thyge Okkels, Cláudia N. Santos, Olga Tikhonova, Alexandre Foito, Ana Rute Neves, Regina Menezes, Isabel Rocha, Inês Costa, Adelaide Braga, Olivier Simon, Rita Rosado-Ramos, Joana Oliveira, Michael Bott, Leen Stougie, Diane Barbay, Lei Pei, Sabine Freitag, Susana Vinga, Sandra Youssef, Patrícia Ferreira

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Dudnik, A, Almeida, A F, Andrade, R, Avila, B, Bañados, P, Barbay, D, Bassard, J E, Benkoulouche, M, Bott, M, Braga, A, Breitel, D, Brennan, R, Bulteau, L, Chanforan, C, Costa, I, Costa, R S, Doostmohammadi, M, Faria, N, Feng, C, Fernandes, A, Ferreira, P, Ferro, R, Foito, A, Freitag, S, Garcia, G, Gaspar, P, Godinho-Pereira, J, Hamberger, B, Hartmann, A, Heider, H, Jardim, C, Julien-Laferriere, A, Kallscheuer, N, Kerbe, W, Kuipers, O P, Li, S, Love, N, Marchetti-Spaccamela, A, Marienhagen, J, Martin, C, Mary, A, Mazurek, V, Meinhart, C, Sevillano, D M, Menezes, R, Naesby, M, Nørholm, M H H, Okkels, F T, Oliveira, J, Ottens, M, Parrot, D, Pei, L, Rocha, I, Rosado-Ramos, R, Rousseau, C, Sagot, M F, Dos Santos, C N, Schmidt, M, Shelenga, T, Shepherd, L, Silva, A R, da Silva, M H, Simon, O, Stahlhut, S G, Solopova, A, Sorokin, A, Stewart, D, Stougie, L, Su, S, Thole, V, Tikhonova, O, Trick, M, Vain, P, Veríssimo, A, Vila-Santa, A, Vinga, S, Vogt, M, Wang, L, Wang, L, Wei, W, Youssef, S, Neves, A R & Forster, J 2018, ' BacHBerry:: BACterial Hosts for production of Bioactive phenolics from bERRY fruits ', Phytochemistry Reviews, vol. 17, no. 2, pp. 291-326 . https://doi.org/10.1007/s11101-017-9532-2
Phytochemistry Reviews, 17, 291-326
Dudnik, A, Almeida, A F, Andrade, R, Bañados, P, Barbay, D, Bassard, J-E, Benkoulouche, M, Bott, M, Braga, A, Breitel, D, Brennan, R, Bulteau, L, Chanforan, C, Costa, I, Costa, R S, Doostmohammadi, M, Faria, N, Feng, C, Fernandes, A, Ferreira, P, Ferro, R, Foito, A, Freitag, S, Garcia, G, Gaspar, P, Godinho-Pereira, J, Hamberger, B, Hartmann, A, Heider, H, Jardim, C, Julien-Laferriere, A, Kallscheuer, N, Kerbe, W, Kuipers, O P, Li, S, Love, N, Marchetti-Spaccamela, A, Marienhagen, J, Martin, C, Mary, A, Mazurek, V, Meinhart, C, Méndez Sevillano, D, Menezes, R, Naesby, M, Nørholm, M H H, Okkels, F T, Oliveira, J, Ottens, M, Parrot, D, Pei, L, Rocha, I, Rosado-Ramos, R, Rousseau, C, Sagot, M-F, Nunes dos Santos, C, Schmidt, M, Shelenga, T, Shepherd, L, Silva, A R, da Silva, M H, Simon, O, Stahlhut, S G, Solopova, A, Sorokin, A, Stewart, D, Stougie, L, Su, S, Thole, V, Tikhonova, O, Trick, M, Vain, P, Veríssimo, A, Vila-Santa, A, Vinga, S, Vogt, M, Wang, L, Wang, L, Wei, W, Youssef, S, Rute Neves, A & Forster, J 2018, ' BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits ', Phytochemistry Reviews, vol. 17, no. 2, pp. 291-326 . https://doi.org/10.1007/s11101-017-9532-2
Phytochemistry Reviews
Phytochemistry Reviews, 2017, pp.1-36. ⟨10.1007/s11101-017-9532-2⟩
Dudnik, A, Almeida, A F, Andrade, R, Avila, B, Bañados, P, Barbay, D, Bassard, J E, Benkoulouche, M, Bott, M, Braga, A, Breitel, D, Brennan, R, Bulteau, L, Chanforan, C, Costa, I, Costa, R S, Doostmohammadi, M, Faria, N, Feng, C, Fernandes, A, Ferreira, P, Ferro, R, Foito, A, Freitag, S, Garcia, G, Gaspar, P, Godinho-Pereira, J, Hamberger, B, Hartmann, A, Heider, H, Jardim, C, Julien-Laferriere, A, Kallscheuer, N, Kerbe, W, Kuipers, O P, Li, S, Love, N, Marchetti-Spaccamela, A, Marienhagen, J, Martin, C, Mary, A, Mazurek, V, Meinhart, C, Sevillano, D M, Menezes, R, Naesby, M, Nørholm, M H H, Okkels, F T, Oliveira, J, Ottens, M, Parrot, D, Pei, L, Rocha, I, Rosado-Ramos, R, Rousseau, C, Sagot, M F, dos Santos, C N, Schmidt, M, Shelenga, T, Shepherd, L, Silva, A R, da Silva, M H, Simon, O, Stahlhut, S G, Solopova, A, Sorokin, A, Stewart, D, Stougie, L, Su, S, Thole, V, Tikhonova, O, Trick, M, Vain, P, Veríssimo, A, Vila-Santa, A, Vinga, S, Vogt, M, Wang, L, Wang, L, Wei, W, Youssef, S, Neves, A R & Forster, J 2018, ' BacHBerry : BACterial Hosts for production of Bioactive phenolics from bERRY fruits ', Phytochemistry Reviews, vol. 17, no. 2, pp. 291-326 . https://doi.org/10.1007/s11101-017-9532-2
Phytochemistry Reviews, Springer Verlag, 2017, pp.1-36. ⟨10.1007/s11101-017-9532-2⟩

BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbec5ef8e68758eef7bbc9e69ce53dbd

Structural and Population Characterization of MrkD, the Adhesive Subunit of Type 3 Fimbriae

Autor: Carsten Struve, Steven Clegg, Dagmara I. Kisiela, Evgeni V. Sokurenko, Karen A. Krogfelt, Steen Gustav Stahlhut, Kristian Hvidtfeldt, Sujay Chattopadhyay

Publikováno v: Journal of Bacteriology. 195:5602-5613

Type 3 fimbriae are adhesive organelles found in enterobacterial pathogens. The fimbriae promote biofilm formation on biotic and abiotic surfaces; however, the exact identity of the receptor for the type 3 fimbriae adhesin, MrkD, remains elusive. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9439a0438cf89f9c007a0ad77ffde566
https://doi.org/10.1128/jb.00753-13

Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

Autor: Steen Gustav Stahlhut, Solvej Siedler, Ana Rute Neves, Jerome Maury, Jochen Förster, Paula Gaspar, Irina Borodina, Edith Angelica Rodriguez Prado, Tomas Strucko

Publikováno v: Stahlhut, S G, Siedler, S, Neves, A R, MAURY, JEROME, Förster, J, Gaspar, P, Borodina, I, Rodriguez Prado, E A & Strucko, T May. 12 2016, Microbial production of the flavonoids garbanzol, resokaempferol and fisetin, Patent No. WO2016071505, IPC No. C07D 311/ 30 A I .
Technical University of Denmark Orbit

The invention provides a genetically modified micro-organism comprising one or more transgene for the production of one or more of the flavonoids garbanzol, resokaempferol and fisetin. The micro-organism may be a bacterial or yeast cell engineered to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1c812227c630289026851b54e2117a1d
http://orbit.dtu.dk/ws/files/124205992/WO2016071505A1.pdf

Klebsiella pneumoniae type 3 fimbriae agglutinate yeast in a mannose-resistant manner

Autor: Karen A. Krogfelt, Carsten Struve, Steen Gustav Stahlhut

Publikováno v: Journal of Medical Microbiology. 61:317-322

The ability of bacterial pathogens to express different fimbrial adhesins plays a significant role in virulence. Thus, specific detection of fimbrial expression is an important task in virulence characterization and epidemiological studies. Most clin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d792aff5fed649603ed6da90d707ba8e
https://doi.org/10.1099/jmm.0.036350-0