Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Steen, Kølvraa"'
Autor:
Lotte Hatt, Mads M Aagaard, Cathrine Bach, Jesper Graakjaer, Steffen Sommer, Inge E Agerholm, Steen Kølvraa, Anders Bojesen
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160319 (2016)
Methylation-based non-invasive prenatal testing of fetal aneuploidies is an alternative method that could possibly improve fetal aneuploidy diagnosis, especially for trisomy 13(T13) and trisomy 18(T18). Our aim was to study the methylation landscape
Externí odkaz:
https://doaj.org/article/11acaa8328cd4a7793775c2bffe36fa5
Autor:
Lotte Hatt, Mads M Aagaard, Jesper Graakjaer, Cathrine Bach, Steffen Sommer, Inge E Agerholm, Steen Kølvraa, Anders Bojesen
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0128918 (2015)
Epigenetic markers for cell free fetal DNA in the maternal blood circulation are highly interesting in the field of non-invasive prenatal testing since such markers will offer a possibility to quantify the amount of fetal DNA derived from different c
Externí odkaz:
https://doaj.org/article/faa1741ddebd40e0b83acd641b05cba8
Autor:
Jacob Mørup Schlütter, Ida Kirkegaard, Olav Bjørn Petersen, Nanna Larsen, Britta Christensen, David M Hougaard, Steen Kølvraa, Niels Uldbjerg
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106934 (2014)
To identify factors influencing the number of fetal cells in maternal blood.A total of 57 pregnant women at a gestational age of weeks 11-14 were included. The number of fetal cells in maternal blood was assessed in 30 ml of blood using specific mark
Externí odkaz:
https://doaj.org/article/8b785067defd46dcb5eb39bb73a947ea
Autor:
Torben Helledie, Marianne Antonius, Rikke V. Sørensen, Ann V. Hertzel, David A. Bernlohr, Steen Kølvraa, Karsten Kristiansen, Susanne Mandrup
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 11, Pp 1740-1751 (2000)
Peroxisome proliferator-activated receptors (PPARs) are activated by a variety of fatty acids, eicosanoids, and hypolipidemic and insulin-sensitizing drugs. Many of these compounds bind avidly to members of a family of small lipid-binding proteins, t
Externí odkaz:
https://doaj.org/article/9311808824a2433eb72858fa1407b0b4
Autor:
Palle Schelde, Amy M. Breman, Else Marie Vestergaard, Elizabeth A. Normand, Chad A. Shaw, Rui Chen, Ignatia B. Van den Veyver, Steen Kølvraa, Sadeem Qdaisat, Li Zhao, Lotte Hatt, Niels Uldbjerg, Laird G. Jackson, Ripudaman Singh, Arthur L. Beaudet
Publikováno v:
Prenatal Diagnosis. 36:1127-1134
Objective Non-invasive prenatal testing (NIPT) based on fetal cells in maternal blood has the advantage over NIPT based on circulating cell-free fetal DNA in that there is no contamination with maternal DNA. This will most likely result in better det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de39c4df20564b065cc02fa59be1b1f1
https://doi.org/10.1002/pd.4948
https://doi.org/10.1002/pd.4948
Publikováno v:
Critical reviews in eukaryotic gene expression. 27(1)
The H2A histone family, member X (H2AX), and Werner (WRN) are important proteins for genome and telomere maintenance. WRN has a major role in genome stability, particularly during DNA replication, transcription, recombination, and repair of DNA doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b04c13d268b0f6f0f0d4d538c337dc
https://pubmed.ncbi.nlm.nih.gov/28436335
https://pubmed.ncbi.nlm.nih.gov/28436335
Autor:
Niels Uldbjerg, Kristine Møller, Lotte Hatt, Britta Christensen, Ripudaman Singh, Jacob Mørup Schlütter, Steen Kølvraa, Rune Hoff Lauridsen, Marie Brinch
Publikováno v:
Prenatal Diagnosis. 34:1066-1072
Objective Fetal cells from the maternal circulation (FCMBs) have the potential to replace cells from amniotic fluid or chorionic villi in a diagnosis of common chromosomal aneuploidies. Good markers for enrichment and identification are lacking. Meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d33ac07e855738d072f1c1055dbabd2
https://doi.org/10.1002/pd.4429
https://doi.org/10.1002/pd.4429
Autor:
Niels Uldbjerg, Lotte Hatt, Ida Kirkegaard, Steen Kølvraa, Cathrine Carlsen Bach, Jacob Mørup Schlütter
Publikováno v:
Prenatal Diagnosis. 34:341-344
Objective If noninvasive prenatal testing using next generation sequencing is to be effective for pregnant women, a cell-free fetal DNA (cffDNA) fraction above 4% is essential unless the depth of sequencing is increased. This study's objective is to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7951d3d3106628737716f88f6d88ffd
https://doi.org/10.1002/pd.4306
https://doi.org/10.1002/pd.4306
Autor:
Rune Hoff Lauridsen, Berthold Huppertz, Marie Brinch, Niels Uldbjerg, Steen Kølvraa, Britta Christensen, Ripudaman Singh, Lotte Hatt, Kristine Møller
Publikováno v:
Hatt, L, Brinch, M, Singh, R, Møller, U K, Lauridsen, R H, Uldbjerg, N, Huppertz, B, Christensen, C B & Kølvraa, S 2014, ' Characterization of Fetal Cells from the Maternal Circulation by Microarray Gene Expression Analysis-Could the Extravillous Trophoblasts Be a Target for Future Cell-Based Non-Invasive Prenatal Diagnosis? ', Fetal Diagnosis and Therapy, vol. 35, pp. 218-227 . https://doi.org/10.1159/000356073
Hatt, L, Brinch, M, Singh, R, Møller, K, Lauridsen, R H, Uldbjerg, N, Huppertz, B, Christensen, B & Kølvraa, S 2014, ' Characterization of fetal cells from the maternal circulation by microarray gene expression analysis-Could the extravillous trophoblasts be a target for future cell-based non-invasive prenatal diagnosis? ', Fetal Diagnosis and Therapy, vol. 35, no. 3, pp. 218-227 . https://doi.org/10.1159/000356073
Hatt, L, Brinch, M, Singh, R, Møller, K, Lauridsen, R H, Uldbjerg, N, Huppertz, B, Christensen, B & Kølvraa, S 2014, ' Characterization of fetal cells from the maternal circulation by microarray gene expression analysis-Could the extravillous trophoblasts be a target for future cell-based non-invasive prenatal diagnosis? ', Fetal Diagnosis and Therapy, vol. 35, no. 3, pp. 218-227 . https://doi.org/10.1159/000356073
Introduction: Circulating fetal cells in maternal blood provide a tool for risk-free, non-invasive prenatal diagnosis. However, fetal cells in the maternal circulation are scarce, and to effectively isolate enough of them for reliable diagnostics, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e69f6d3608390fbff33f4477560f5e
https://doi.org/10.1159/000356073
https://doi.org/10.1159/000356073
Autor:
Laila Bendix, Mogens Fenger, Allan Linneberg, Mikael Thinggaard, Kirsten Avlund, Steen Kølvraa, Merete Osler
Publikováno v:
Bendix, L, Thinggaard, M, Fenger, M, Kølvraa, S, Avlund, K, Linneberg, A R & Osler, M 2014, ' Longitudinal Changes in Leukocyte Telomere Length and Mortality in Humans ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 69 A, no. 2, pp. 231-239 . https://doi.org/10.1093/gerona/glt153
Background. Leukocyte telomere length (LTL) ostensibly shortens with age and has been moderately associated with mortality. In humans, these findings have come almost solely from cross-sectional studies. Only recently has LTL shortening within indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d79a5e2765b8407676c53eeaa0fb942
https://doi.org/10.1093/gerona/glt153
https://doi.org/10.1093/gerona/glt153