Rate and affinity binding constants determined by SPR spectroscopy reveal differential antigenicity of HIV gp120 and gp140

Autor: Gearhart TL, Steckbeck JD, Craigo JK, Montelaro RC

Publikováno v: Retrovirology, Vol 9, Iss Suppl 2, p P59 (2012)

Externí odkaz: https://doaj.org/article/50479e510b6249bfb94c5c304e54045a

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Engineered peptide PLG0206 overcomes limitations of a challenging antimicrobial drug class.

Autor: Huang DB; Peptilogics, Pittsburgh, Pennsylvania, United States of America., Brothers KM; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Mandell JB; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Taguchi M; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Orthopedic Surgery, Tokyo Women's Medical University, Medical Center East, Tokyo, Japan., Alexander PG; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Parker DM; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Shinabarger D; Micromyx, Kalamazoo, Michigan, United States of America., Pillar C; Micromyx, Kalamazoo, Michigan, United States of America., Morrissey I; IHMA, Monthey, Switzerland., Hawser S; IHMA, Monthey, Switzerland., Ghahramani P; Inncelerex, Jersey City, New Jersey, United States of America., Dobbins D; Peptilogics, Pittsburgh, Pennsylvania, United States of America., Pachuda N; Peptilogics, Pittsburgh, Pennsylvania, United States of America., Montelaro R; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Steckbeck JD; Peptilogics, Pittsburgh, Pennsylvania, United States of America., Urish KL; Department of Orthopedic Surgery, Arthritis and Arthroplasty Design Group, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; The Bone and Joint Center, Magee Women's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America.; Department of Bioengineering, and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

Publikováno v: PloS one [PLoS One] 2022 Sep 16; Vol. 17 (9), pp. e0274815. Date of Electronic Publication: 2022 Sep 16 (Print Publication: 2022).